CA2628407C - High impedance system for generating electric fields and method of use - Google Patents
High impedance system for generating electric fields and method of use Download PDFInfo
- Publication number
- CA2628407C CA2628407C CA2628407A CA2628407A CA2628407C CA 2628407 C CA2628407 C CA 2628407C CA 2628407 A CA2628407 A CA 2628407A CA 2628407 A CA2628407 A CA 2628407A CA 2628407 C CA2628407 C CA 2628407C
- Authority
- CA
- Canada
- Prior art keywords
- fluid
- electric field
- electrodes
- subject
- pathway
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000005684 electric field Effects 0.000 title claims abstract description 40
- 238000000034 method Methods 0.000 title claims abstract description 38
- 239000012530 fluid Substances 0.000 claims abstract description 74
- 239000000463 material Substances 0.000 claims abstract description 20
- 239000003989 dielectric material Substances 0.000 claims abstract description 18
- 239000007788 liquid Substances 0.000 claims abstract description 16
- 238000010438 heat treatment Methods 0.000 claims abstract description 10
- 239000007789 gas Substances 0.000 claims abstract description 3
- 238000004520 electroporation Methods 0.000 claims description 28
- 230000037361 pathway Effects 0.000 claims description 26
- 238000012360 testing method Methods 0.000 claims description 19
- 239000004020 conductor Substances 0.000 claims description 12
- 230000002441 reversible effect Effects 0.000 claims description 8
- 239000000919 ceramic Substances 0.000 claims description 6
- 230000005518 electrochemistry Effects 0.000 claims description 6
- 230000002427 irreversible effect Effects 0.000 claims description 6
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- 230000003068 static effect Effects 0.000 claims description 5
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- 239000004593 Epoxy Substances 0.000 claims description 3
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
- A61N1/0416—Anode and cathode
- A61N1/042—Material of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
- A61N1/0416—Anode and cathode
- A61N1/0424—Shape of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H1/00—Generating plasma; Handling plasma
- H05H1/24—Generating plasma
- H05H1/2406—Generating plasma using dielectric barrier discharges, i.e. with a dielectric interposed between the electrodes
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H1/00—Generating plasma; Handling plasma
- H05H1/24—Generating plasma
- H05H1/2406—Generating plasma using dielectric barrier discharges, i.e. with a dielectric interposed between the electrodes
- H05H1/2443—Generating plasma using dielectric barrier discharges, i.e. with a dielectric interposed between the electrodes the plasma fluid flowing through a dielectric tube
- H05H1/246—Generating plasma using dielectric barrier discharges, i.e. with a dielectric interposed between the electrodes the plasma fluid flowing through a dielectric tube the plasma being activated using external electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44713—Particularly adapted electric power supply
Landscapes
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Plasma & Fusion (AREA)
- Biophysics (AREA)
- Radiology & Medical Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Electrochemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Fluid Mechanics (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Water Treatment By Electricity Or Magnetism (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73288805P | 2005-11-02 | 2005-11-02 | |
| US60/732,888 | 2005-11-02 | ||
| US11/551,584 | 2006-10-20 | ||
| US11/551,584 US8226811B2 (en) | 2005-11-02 | 2006-10-20 | High impedance system for generating electric fields and method of use |
| PCT/US2006/042712 WO2007056027A1 (en) | 2005-11-02 | 2006-10-31 | High impedance system for generating electric fields and method of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2628407A1 CA2628407A1 (en) | 2007-05-18 |
| CA2628407C true CA2628407C (en) | 2014-08-05 |
Family
ID=37994810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2628407A Expired - Fee Related CA2628407C (en) | 2005-11-02 | 2006-10-31 | High impedance system for generating electric fields and method of use |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US8226811B2 (enExample) |
| EP (1) | EP1952133B1 (enExample) |
| JP (1) | JP5607304B2 (enExample) |
| KR (1) | KR101361498B1 (enExample) |
| AU (1) | AU2006311979B2 (enExample) |
| BR (1) | BRPI0618420A2 (enExample) |
| CA (1) | CA2628407C (enExample) |
| NZ (1) | NZ603542A (enExample) |
| RU (1) | RU2408006C2 (enExample) |
| UA (1) | UA95262C2 (enExample) |
| WO (1) | WO2007056027A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10996210B2 (en) | 2018-01-02 | 2021-05-04 | Transportation Ip Holdings, Llc | Vehicle system with sensor probe assembly for monitoring oil health |
| US8821365B2 (en) | 2009-07-29 | 2014-09-02 | Thoratec Corporation | Rotation drive device and centrifugal pump apparatus using the same |
| JP5969979B2 (ja) | 2011-03-28 | 2016-08-17 | ソーラテック コーポレイション | 回転駆動装置およびそれを用いた遠心式ポンプ装置 |
| CN102720490B (zh) * | 2012-06-29 | 2014-11-26 | 西南石油大学 | 一种直井随钻钻井液油气信息测量方法及测量仪器 |
| CN102691498B (zh) * | 2012-06-29 | 2014-11-26 | 西南石油大学 | 一种水平井随钻泥浆电参数测量仪 |
| US20140221877A1 (en) * | 2013-02-01 | 2014-08-07 | Moshe Ein-Gal | Pressure-assisted irreversible electroporation |
| US10052420B2 (en) | 2013-04-30 | 2018-08-21 | Tc1 Llc | Heart beat identification and pump speed synchronization |
| US9623161B2 (en) | 2014-08-26 | 2017-04-18 | Tc1 Llc | Blood pump and method of suction detection |
| EP3256183B1 (en) | 2015-02-11 | 2025-08-13 | Tc1 Llc | Heart beat identification and pump speed synchronization |
| US10371152B2 (en) | 2015-02-12 | 2019-08-06 | Tc1 Llc | Alternating pump gaps |
| WO2016130944A1 (en) | 2015-02-12 | 2016-08-18 | Thoratec Corporation | System and method for controlling the position of a levitated rotor |
| US10245361B2 (en) | 2015-02-13 | 2019-04-02 | Tc1 Llc | Impeller suspension mechanism for heart pump |
| US10117983B2 (en) | 2015-11-16 | 2018-11-06 | Tc1 Llc | Pressure/flow characteristic modification of a centrifugal pump in a ventricular assist device |
| US10835734B1 (en) | 2017-08-21 | 2020-11-17 | Wayne May | High and low impedance systems and methods for the generation and use of constant intensity electric fields |
| EP3666882A1 (en) | 2018-12-12 | 2020-06-17 | AIT Austrian Institute of Technology GmbH | Specific electroporation and lysis of eukaryotic cells |
| CN113281380B (zh) * | 2021-05-20 | 2024-06-11 | 重庆大学 | 一种摩擦纳米发电机驱动的电介质陷阱态测量和成像系统及方法 |
| ES2991715B2 (es) * | 2024-03-22 | 2025-06-27 | Gil Daniel Serrano | Electrodo con proteccion frente a arco electrico |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2919235A (en) * | 1956-11-06 | 1959-12-29 | Paul S Roller | Electrolytic method and apparatus for the production of metal hydroxide |
| GB8621948D0 (en) * | 1986-09-11 | 1986-10-15 | Gibbs R W | Destroying bacteria |
| US4822470A (en) * | 1987-10-09 | 1989-04-18 | Baylor College Of Medicine | Method of and apparatus for cell poration and cell fusion using radiofrequency electrical pulses |
| US5134070A (en) * | 1990-06-04 | 1992-07-28 | Casnig Dael R | Method and device for cell cultivation on electrodes |
| US5234555A (en) * | 1991-02-05 | 1993-08-10 | Ibbott Jack Kenneth | Method and apparatus for ionizing fluids utilizing a capacitive effect |
| US5983131A (en) * | 1995-08-11 | 1999-11-09 | Massachusetts Institute Of Technology | Apparatus and method for electroporation of tissue |
| US5690978A (en) * | 1996-09-30 | 1997-11-25 | Ohio State University | High voltage pulsed electric field treatment chambers for the preservation of liquid food products |
| US6090617A (en) * | 1996-12-05 | 2000-07-18 | Entremed, Inc. | Flow electroporation chamber with electrodes having a crystalline metal nitride coating |
| GB9908681D0 (en) * | 1999-04-16 | 1999-06-09 | Central Research Lab Ltd | Apparatus for, and method of, introducing a substance into an object |
| US6455014B1 (en) * | 1999-05-14 | 2002-09-24 | Mesosystems Technology, Inc. | Decontamination of fluids or objects contaminated with chemical or biological agents using a distributed plasma reactor |
| US6689380B1 (en) * | 1999-05-17 | 2004-02-10 | Kevin S. Marchitto | Remote and local controlled delivery of pharmaceutical compounds using electromagnetic energy |
| CA2376368C (en) * | 1999-06-08 | 2009-08-11 | Altea Technologies, Inc. | Apparatus for microporation of biological membranes using thin film tissue interface devices, and method therefor |
| US6300108B1 (en) * | 1999-07-21 | 2001-10-09 | The Regents Of The University Of California | Controlled electroporation and mass transfer across cell membranes |
| US7192553B2 (en) * | 1999-12-15 | 2007-03-20 | Plasmasol Corporation | In situ sterilization and decontamination system using a non-thermal plasma discharge |
| GB9930718D0 (en) * | 1999-12-24 | 2000-02-16 | Central Research Lab Ltd | Apparatus for and method of making electrical measurements on objects |
| AU2001228841A1 (en) * | 2000-01-27 | 2001-08-07 | The Mollennium Laboratories | Molecule transferring device, auxiliary for molecule transferring device, and molecule transferring method |
| US6868289B2 (en) * | 2002-10-02 | 2005-03-15 | Standen Ltd. | Apparatus for treating a tumor or the like and articles incorporating the apparatus for treatment of the tumor |
| US6928318B2 (en) | 2000-05-22 | 2005-08-09 | Merck & Co., Inc. | System and method for assessing the performance of a pharmaceutical agent delivery system |
| US6911225B2 (en) * | 2001-05-07 | 2005-06-28 | Regents Of The University Of Minnesota | Method and apparatus for non-thermal pasteurization of living-mammal-instillable liquids |
| US6562386B2 (en) | 2001-05-07 | 2003-05-13 | Regents Of The University Of Minnesota | Method and apparatus for non-thermal pasteurization |
| US7011790B2 (en) * | 2001-05-07 | 2006-03-14 | Regents Of The University Of Minnesota | Non-thermal disinfection of biological fluids using non-thermal plasma |
| KR20040077658A (ko) | 2001-11-02 | 2004-09-06 | 플라스마솔 코포레이션 | 플라스마 방전 및 필터를 이용한 살균 및 오염제거 시스템 |
| ATE412447T1 (de) | 2002-05-23 | 2008-11-15 | Gendel Ltd | Ablationsvorrichtung |
| RU26004U1 (ru) * | 2002-05-29 | 2002-11-10 | Общество с ограниченной ответственностью Центр по изготовлению медицинской техники "Экстратерм" | Устройство для высокочастотной терапии и система ориентации электродов для него |
| JP2004202086A (ja) | 2002-12-26 | 2004-07-22 | Teikoku Seiyaku Co Ltd | エレクトロポレーション用薬物投与部、エレクトロポレーション用薬物投与システム、及びエレクトロポレーション用薬物投与方法 |
| JP4037258B2 (ja) * | 2002-12-26 | 2008-01-23 | 株式会社吉野工業所 | 櫛付き容器 |
| JP2004248653A (ja) | 2003-02-22 | 2004-09-09 | Minoru Seki | 流通型エレクトロポレーション用電極装置およびそれを用いた細胞への物質導入方法 |
| JP4319427B2 (ja) * | 2003-02-28 | 2009-08-26 | 株式会社東芝 | 医用超音波照射装置 |
| WO2007021994A2 (en) | 2005-08-12 | 2007-02-22 | Maxcyte, Inc. | Electrode shielding for electroporation |
| CA2678450A1 (en) * | 2007-03-01 | 2008-09-04 | Queen's University At Kingston | Planar electroporation apparatus and method |
-
2006
- 2006-10-20 US US11/551,584 patent/US8226811B2/en not_active Expired - Fee Related
- 2006-10-31 NZ NZ603542A patent/NZ603542A/xx not_active IP Right Cessation
- 2006-10-31 CA CA2628407A patent/CA2628407C/en not_active Expired - Fee Related
- 2006-10-31 BR BRPI0618420-0A patent/BRPI0618420A2/pt not_active IP Right Cessation
- 2006-10-31 EP EP06827315.0A patent/EP1952133B1/en not_active Not-in-force
- 2006-10-31 WO PCT/US2006/042712 patent/WO2007056027A1/en not_active Ceased
- 2006-10-31 RU RU2008121962/28A patent/RU2408006C2/ru not_active IP Right Cessation
- 2006-10-31 UA UAA200807394A patent/UA95262C2/uk unknown
- 2006-10-31 KR KR1020087013250A patent/KR101361498B1/ko not_active Expired - Fee Related
- 2006-10-31 JP JP2008539011A patent/JP5607304B2/ja not_active Expired - Fee Related
- 2006-10-31 AU AU2006311979A patent/AU2006311979B2/en not_active Ceased
-
2010
- 2010-04-29 US US12/769,872 patent/US8221596B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR101361498B1 (ko) | 2014-02-12 |
| WO2007056027A1 (en) | 2007-05-18 |
| US8221596B2 (en) | 2012-07-17 |
| EP1952133B1 (en) | 2016-03-30 |
| US20070095648A1 (en) | 2007-05-03 |
| JP2009515168A (ja) | 2009-04-09 |
| RU2008121962A (ru) | 2009-12-10 |
| AU2006311979A1 (en) | 2007-05-18 |
| CA2628407A1 (en) | 2007-05-18 |
| US8226811B2 (en) | 2012-07-24 |
| AU2006311979B2 (en) | 2013-01-24 |
| UA95262C2 (uk) | 2011-07-25 |
| JP5607304B2 (ja) | 2014-10-15 |
| RU2408006C2 (ru) | 2010-12-27 |
| NZ603542A (en) | 2013-03-28 |
| BRPI0618420A2 (pt) | 2012-10-30 |
| EP1952133A4 (en) | 2011-08-31 |
| US20110139608A1 (en) | 2011-06-16 |
| EP1952133A1 (en) | 2008-08-06 |
| KR20080080518A (ko) | 2008-09-04 |
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