AU2006311979B2 - High impedance system for generating electric fields and method of use - Google Patents

High impedance system for generating electric fields and method of use Download PDF

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Publication number
AU2006311979B2
AU2006311979B2 AU2006311979A AU2006311979A AU2006311979B2 AU 2006311979 B2 AU2006311979 B2 AU 2006311979B2 AU 2006311979 A AU2006311979 A AU 2006311979A AU 2006311979 A AU2006311979 A AU 2006311979A AU 2006311979 B2 AU2006311979 B2 AU 2006311979B2
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AU
Australia
Prior art keywords
fluid
electrodes
electric field
subject
space
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Ceased
Application number
AU2006311979A
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English (en)
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AU2006311979A1 (en
Inventor
Wayne A. May
Peter Ruben
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MAY-RUBEN TECHNOLOGIES Inc
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MAY RUBEN TECHNOLOGIES Inc
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Publication of AU2006311979A1 publication Critical patent/AU2006311979A1/en
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Ceased legal-status Critical Current
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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0412Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A61N1/0416Anode and cathode
    • A61N1/042Material of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0412Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A61N1/0416Anode and cathode
    • A61N1/0424Shape of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05HPLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H1/00Generating plasma; Handling plasma
    • H05H1/24Generating plasma
    • H05H1/2406Generating plasma using dielectric barrier discharges, i.e. with a dielectric interposed between the electrodes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44713Particularly adapted electric power supply
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05HPLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H1/00Generating plasma; Handling plasma
    • H05H1/24Generating plasma
    • H05H1/2406Generating plasma using dielectric barrier discharges, i.e. with a dielectric interposed between the electrodes
    • H05H1/2443Generating plasma using dielectric barrier discharges, i.e. with a dielectric interposed between the electrodes the plasma fluid flowing through a dielectric tube
    • H05H1/246Generating plasma using dielectric barrier discharges, i.e. with a dielectric interposed between the electrodes the plasma fluid flowing through a dielectric tube the plasma being activated using external electrodes

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  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Plasma & Fusion (AREA)
  • Biophysics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Electrochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Fluid Mechanics (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Water Treatment By Electricity Or Magnetism (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AU2006311979A 2005-11-02 2006-10-31 High impedance system for generating electric fields and method of use Ceased AU2006311979B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US73288805P 2005-11-02 2005-11-02
US60/732,888 2005-11-02
US11/551,584 2006-10-20
US11/551,584 US8226811B2 (en) 2005-11-02 2006-10-20 High impedance system for generating electric fields and method of use
PCT/US2006/042712 WO2007056027A1 (en) 2005-11-02 2006-10-31 High impedance system for generating electric fields and method of use

Publications (2)

Publication Number Publication Date
AU2006311979A1 AU2006311979A1 (en) 2007-05-18
AU2006311979B2 true AU2006311979B2 (en) 2013-01-24

Family

ID=37994810

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006311979A Ceased AU2006311979B2 (en) 2005-11-02 2006-10-31 High impedance system for generating electric fields and method of use

Country Status (11)

Country Link
US (2) US8226811B2 (enExample)
EP (1) EP1952133B1 (enExample)
JP (1) JP5607304B2 (enExample)
KR (1) KR101361498B1 (enExample)
AU (1) AU2006311979B2 (enExample)
BR (1) BRPI0618420A2 (enExample)
CA (1) CA2628407C (enExample)
NZ (1) NZ603542A (enExample)
RU (1) RU2408006C2 (enExample)
UA (1) UA95262C2 (enExample)
WO (1) WO2007056027A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10996210B2 (en) 2018-01-02 2021-05-04 Transportation Ip Holdings, Llc Vehicle system with sensor probe assembly for monitoring oil health
US8821365B2 (en) 2009-07-29 2014-09-02 Thoratec Corporation Rotation drive device and centrifugal pump apparatus using the same
JP5969979B2 (ja) 2011-03-28 2016-08-17 ソーラテック コーポレイション 回転駆動装置およびそれを用いた遠心式ポンプ装置
CN102720490B (zh) * 2012-06-29 2014-11-26 西南石油大学 一种直井随钻钻井液油气信息测量方法及测量仪器
CN102691498B (zh) * 2012-06-29 2014-11-26 西南石油大学 一种水平井随钻泥浆电参数测量仪
US20140221877A1 (en) * 2013-02-01 2014-08-07 Moshe Ein-Gal Pressure-assisted irreversible electroporation
US10052420B2 (en) 2013-04-30 2018-08-21 Tc1 Llc Heart beat identification and pump speed synchronization
US9623161B2 (en) 2014-08-26 2017-04-18 Tc1 Llc Blood pump and method of suction detection
EP3256183B1 (en) 2015-02-11 2025-08-13 Tc1 Llc Heart beat identification and pump speed synchronization
US10371152B2 (en) 2015-02-12 2019-08-06 Tc1 Llc Alternating pump gaps
WO2016130944A1 (en) 2015-02-12 2016-08-18 Thoratec Corporation System and method for controlling the position of a levitated rotor
US10245361B2 (en) 2015-02-13 2019-04-02 Tc1 Llc Impeller suspension mechanism for heart pump
US10117983B2 (en) 2015-11-16 2018-11-06 Tc1 Llc Pressure/flow characteristic modification of a centrifugal pump in a ventricular assist device
US10835734B1 (en) 2017-08-21 2020-11-17 Wayne May High and low impedance systems and methods for the generation and use of constant intensity electric fields
EP3666882A1 (en) 2018-12-12 2020-06-17 AIT Austrian Institute of Technology GmbH Specific electroporation and lysis of eukaryotic cells
CN113281380B (zh) * 2021-05-20 2024-06-11 重庆大学 一种摩擦纳米发电机驱动的电介质陷阱态测量和成像系统及方法
ES2991715B2 (es) * 2024-03-22 2025-06-27 Gil Daniel Serrano Electrodo con proteccion frente a arco electrico

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5690978A (en) * 1996-09-30 1997-11-25 Ohio State University High voltage pulsed electric field treatment chambers for the preservation of liquid food products
US5983131A (en) * 1995-08-11 1999-11-09 Massachusetts Institute Of Technology Apparatus and method for electroporation of tissue
US6090617A (en) * 1996-12-05 2000-07-18 Entremed, Inc. Flow electroporation chamber with electrodes having a crystalline metal nitride coating

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2919235A (en) * 1956-11-06 1959-12-29 Paul S Roller Electrolytic method and apparatus for the production of metal hydroxide
GB8621948D0 (en) * 1986-09-11 1986-10-15 Gibbs R W Destroying bacteria
US4822470A (en) * 1987-10-09 1989-04-18 Baylor College Of Medicine Method of and apparatus for cell poration and cell fusion using radiofrequency electrical pulses
US5134070A (en) * 1990-06-04 1992-07-28 Casnig Dael R Method and device for cell cultivation on electrodes
US5234555A (en) * 1991-02-05 1993-08-10 Ibbott Jack Kenneth Method and apparatus for ionizing fluids utilizing a capacitive effect
GB9908681D0 (en) * 1999-04-16 1999-06-09 Central Research Lab Ltd Apparatus for, and method of, introducing a substance into an object
US6455014B1 (en) * 1999-05-14 2002-09-24 Mesosystems Technology, Inc. Decontamination of fluids or objects contaminated with chemical or biological agents using a distributed plasma reactor
US6689380B1 (en) * 1999-05-17 2004-02-10 Kevin S. Marchitto Remote and local controlled delivery of pharmaceutical compounds using electromagnetic energy
CA2376368C (en) * 1999-06-08 2009-08-11 Altea Technologies, Inc. Apparatus for microporation of biological membranes using thin film tissue interface devices, and method therefor
US6300108B1 (en) * 1999-07-21 2001-10-09 The Regents Of The University Of California Controlled electroporation and mass transfer across cell membranes
US7192553B2 (en) * 1999-12-15 2007-03-20 Plasmasol Corporation In situ sterilization and decontamination system using a non-thermal plasma discharge
GB9930718D0 (en) * 1999-12-24 2000-02-16 Central Research Lab Ltd Apparatus for and method of making electrical measurements on objects
AU2001228841A1 (en) * 2000-01-27 2001-08-07 The Mollennium Laboratories Molecule transferring device, auxiliary for molecule transferring device, and molecule transferring method
US6868289B2 (en) * 2002-10-02 2005-03-15 Standen Ltd. Apparatus for treating a tumor or the like and articles incorporating the apparatus for treatment of the tumor
US6928318B2 (en) 2000-05-22 2005-08-09 Merck & Co., Inc. System and method for assessing the performance of a pharmaceutical agent delivery system
US6911225B2 (en) * 2001-05-07 2005-06-28 Regents Of The University Of Minnesota Method and apparatus for non-thermal pasteurization of living-mammal-instillable liquids
US6562386B2 (en) 2001-05-07 2003-05-13 Regents Of The University Of Minnesota Method and apparatus for non-thermal pasteurization
US7011790B2 (en) * 2001-05-07 2006-03-14 Regents Of The University Of Minnesota Non-thermal disinfection of biological fluids using non-thermal plasma
KR20040077658A (ko) 2001-11-02 2004-09-06 플라스마솔 코포레이션 플라스마 방전 및 필터를 이용한 살균 및 오염제거 시스템
ATE412447T1 (de) 2002-05-23 2008-11-15 Gendel Ltd Ablationsvorrichtung
RU26004U1 (ru) * 2002-05-29 2002-11-10 Общество с ограниченной ответственностью Центр по изготовлению медицинской техники "Экстратерм" Устройство для высокочастотной терапии и система ориентации электродов для него
JP2004202086A (ja) 2002-12-26 2004-07-22 Teikoku Seiyaku Co Ltd エレクトロポレーション用薬物投与部、エレクトロポレーション用薬物投与システム、及びエレクトロポレーション用薬物投与方法
JP4037258B2 (ja) * 2002-12-26 2008-01-23 株式会社吉野工業所 櫛付き容器
JP2004248653A (ja) 2003-02-22 2004-09-09 Minoru Seki 流通型エレクトロポレーション用電極装置およびそれを用いた細胞への物質導入方法
JP4319427B2 (ja) * 2003-02-28 2009-08-26 株式会社東芝 医用超音波照射装置
WO2007021994A2 (en) 2005-08-12 2007-02-22 Maxcyte, Inc. Electrode shielding for electroporation
CA2678450A1 (en) * 2007-03-01 2008-09-04 Queen's University At Kingston Planar electroporation apparatus and method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5983131A (en) * 1995-08-11 1999-11-09 Massachusetts Institute Of Technology Apparatus and method for electroporation of tissue
US5690978A (en) * 1996-09-30 1997-11-25 Ohio State University High voltage pulsed electric field treatment chambers for the preservation of liquid food products
US6090617A (en) * 1996-12-05 2000-07-18 Entremed, Inc. Flow electroporation chamber with electrodes having a crystalline metal nitride coating

Also Published As

Publication number Publication date
KR101361498B1 (ko) 2014-02-12
WO2007056027A1 (en) 2007-05-18
US8221596B2 (en) 2012-07-17
CA2628407C (en) 2014-08-05
EP1952133B1 (en) 2016-03-30
US20070095648A1 (en) 2007-05-03
JP2009515168A (ja) 2009-04-09
RU2008121962A (ru) 2009-12-10
AU2006311979A1 (en) 2007-05-18
CA2628407A1 (en) 2007-05-18
US8226811B2 (en) 2012-07-24
UA95262C2 (uk) 2011-07-25
JP5607304B2 (ja) 2014-10-15
RU2408006C2 (ru) 2010-12-27
NZ603542A (en) 2013-03-28
BRPI0618420A2 (pt) 2012-10-30
EP1952133A4 (en) 2011-08-31
US20110139608A1 (en) 2011-06-16
EP1952133A1 (en) 2008-08-06
KR20080080518A (ko) 2008-09-04

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