BRPI0618420A2 - sistema de alta impedáncia para geração de um campo elétrico e método de uso. - Google Patents
sistema de alta impedáncia para geração de um campo elétrico e método de uso. Download PDFInfo
- Publication number
- BRPI0618420A2 BRPI0618420A2 BRPI0618420-0A BRPI0618420A BRPI0618420A2 BR PI0618420 A2 BRPI0618420 A2 BR PI0618420A2 BR PI0618420 A BRPI0618420 A BR PI0618420A BR PI0618420 A2 BRPI0618420 A2 BR PI0618420A2
- Authority
- BR
- Brazil
- Prior art keywords
- fluid
- electric field
- question
- electrodes
- space
- Prior art date
Links
- 230000005684 electric field Effects 0.000 title claims abstract description 62
- 238000000034 method Methods 0.000 title claims abstract description 35
- 239000012530 fluid Substances 0.000 claims abstract description 89
- 239000000463 material Substances 0.000 claims abstract description 29
- 239000003989 dielectric material Substances 0.000 claims abstract description 20
- 239000003990 capacitor Substances 0.000 claims abstract description 13
- 238000010438 heat treatment Methods 0.000 claims abstract description 11
- 238000011282 treatment Methods 0.000 claims description 22
- 238000012360 testing method Methods 0.000 claims description 21
- 150000001875 compounds Chemical class 0.000 claims description 13
- 239000004020 conductor Substances 0.000 claims description 12
- 230000004888 barrier function Effects 0.000 claims description 9
- 239000000919 ceramic Substances 0.000 claims description 7
- 239000011248 coating agent Substances 0.000 claims description 7
- 238000000576 coating method Methods 0.000 claims description 7
- 230000003068 static effect Effects 0.000 claims description 7
- 239000004593 Epoxy Substances 0.000 claims description 4
- 230000005518 electrochemistry Effects 0.000 claims description 3
- 239000002245 particle Substances 0.000 claims description 3
- 239000012799 electrically-conductive coating Substances 0.000 claims 3
- 239000007792 gaseous phase Substances 0.000 claims 2
- 239000007791 liquid phase Substances 0.000 claims 2
- 239000007790 solid phase Substances 0.000 claims 2
- 239000007788 liquid Substances 0.000 abstract description 14
- 238000005265 energy consumption Methods 0.000 abstract description 6
- 230000015572 biosynthetic process Effects 0.000 abstract description 5
- 238000003487 electrochemical reaction Methods 0.000 abstract description 5
- 239000007789 gas Substances 0.000 abstract description 2
- 239000007787 solid Substances 0.000 abstract description 2
- 238000009825 accumulation Methods 0.000 abstract 1
- 238000004520 electroporation Methods 0.000 description 27
- 210000004027 cell Anatomy 0.000 description 22
- 230000000694 effects Effects 0.000 description 21
- 206010012601 diabetes mellitus Diseases 0.000 description 13
- 241000700159 Rattus Species 0.000 description 12
- 230000009471 action Effects 0.000 description 12
- 208000004454 Hyperalgesia Diseases 0.000 description 11
- 239000012528 membrane Substances 0.000 description 8
- 238000009928 pasteurization Methods 0.000 description 8
- 230000005855 radiation Effects 0.000 description 7
- 210000000170 cell membrane Anatomy 0.000 description 6
- 238000010586 diagram Methods 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 230000002441 reversible effect Effects 0.000 description 6
- 230000034994 death Effects 0.000 description 5
- 230000002427 irreversible effect Effects 0.000 description 5
- 230000009467 reduction Effects 0.000 description 5
- 238000007920 subcutaneous administration Methods 0.000 description 5
- 230000001954 sterilising effect Effects 0.000 description 4
- 238000004659 sterilization and disinfection Methods 0.000 description 4
- LIMFPAAAIVQRRD-BCGVJQADSA-N N-[2-[(3S,4R)-3-fluoro-4-methoxypiperidin-1-yl]pyrimidin-4-yl]-8-[(2R,3S)-2-methyl-3-(methylsulfonylmethyl)azetidin-1-yl]-5-propan-2-ylisoquinolin-3-amine Chemical compound F[C@H]1CN(CC[C@H]1OC)C1=NC=CC(=N1)NC=1N=CC2=C(C=CC(=C2C=1)C(C)C)N1[C@@H]([C@H](C1)CS(=O)(=O)C)C LIMFPAAAIVQRRD-BCGVJQADSA-N 0.000 description 3
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 238000001825 field-flow fractionation Methods 0.000 description 3
- 230000002779 inactivation Effects 0.000 description 3
- 230000002503 metabolic effect Effects 0.000 description 3
- 239000004417 polycarbonate Substances 0.000 description 3
- 229920000515 polycarbonate Polymers 0.000 description 3
- 239000011148 porous material Substances 0.000 description 3
- 238000001890 transfection Methods 0.000 description 3
- 238000012546 transfer Methods 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 230000030833 cell death Effects 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 238000001962 electrophoresis Methods 0.000 description 2
- 230000000670 limiting effect Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 230000008823 permeabilization Effects 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 229910052709 silver Inorganic materials 0.000 description 2
- 239000004332 silver Substances 0.000 description 2
- 239000006228 supernatant Substances 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 239000004233 Indanthrene blue RS Substances 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 238000011138 biotechnological process Methods 0.000 description 1
- 239000002800 charge carrier Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000001186 cumulative effect Effects 0.000 description 1
- 230000001086 cytosolic effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 210000003722 extracellular fluid Anatomy 0.000 description 1
- 238000005194 fractionation Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 238000010353 genetic engineering Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000011005 laboratory method Methods 0.000 description 1
- 150000002605 large molecules Chemical class 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000004377 microelectronic Methods 0.000 description 1
- 238000005459 micromachining Methods 0.000 description 1
- 231100001160 nonlethal Toxicity 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 230000021715 photosynthesis, light harvesting Effects 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 230000010287 polarization Effects 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000000392 somatic effect Effects 0.000 description 1
- 230000007847 structural defect Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
- A61N1/0416—Anode and cathode
- A61N1/042—Material of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
- A61N1/0416—Anode and cathode
- A61N1/0424—Shape of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H1/00—Generating plasma; Handling plasma
- H05H1/24—Generating plasma
- H05H1/2406—Generating plasma using dielectric barrier discharges, i.e. with a dielectric interposed between the electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44713—Particularly adapted electric power supply
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H1/00—Generating plasma; Handling plasma
- H05H1/24—Generating plasma
- H05H1/2406—Generating plasma using dielectric barrier discharges, i.e. with a dielectric interposed between the electrodes
- H05H1/2443—Generating plasma using dielectric barrier discharges, i.e. with a dielectric interposed between the electrodes the plasma fluid flowing through a dielectric tube
- H05H1/246—Generating plasma using dielectric barrier discharges, i.e. with a dielectric interposed between the electrodes the plasma fluid flowing through a dielectric tube the plasma being activated using external electrodes
Landscapes
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Plasma & Fusion (AREA)
- Biophysics (AREA)
- Radiology & Medical Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Electrochemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Fluid Mechanics (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Water Treatment By Electricity Or Magnetism (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73288805P | 2005-11-02 | 2005-11-02 | |
| US60/732,888 | 2005-11-02 | ||
| US11/551,584 | 2006-10-20 | ||
| US11/551,584 US8226811B2 (en) | 2005-11-02 | 2006-10-20 | High impedance system for generating electric fields and method of use |
| PCT/US2006/042712 WO2007056027A1 (en) | 2005-11-02 | 2006-10-31 | High impedance system for generating electric fields and method of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0618420A2 true BRPI0618420A2 (pt) | 2012-10-30 |
Family
ID=37994810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0618420-0A BRPI0618420A2 (pt) | 2005-11-02 | 2006-10-31 | sistema de alta impedáncia para geração de um campo elétrico e método de uso. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US8226811B2 (enExample) |
| EP (1) | EP1952133B1 (enExample) |
| JP (1) | JP5607304B2 (enExample) |
| KR (1) | KR101361498B1 (enExample) |
| AU (1) | AU2006311979B2 (enExample) |
| BR (1) | BRPI0618420A2 (enExample) |
| CA (1) | CA2628407C (enExample) |
| NZ (1) | NZ603542A (enExample) |
| RU (1) | RU2408006C2 (enExample) |
| UA (1) | UA95262C2 (enExample) |
| WO (1) | WO2007056027A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10996210B2 (en) | 2018-01-02 | 2021-05-04 | Transportation Ip Holdings, Llc | Vehicle system with sensor probe assembly for monitoring oil health |
| US8821365B2 (en) | 2009-07-29 | 2014-09-02 | Thoratec Corporation | Rotation drive device and centrifugal pump apparatus using the same |
| JP5969979B2 (ja) | 2011-03-28 | 2016-08-17 | ソーラテック コーポレイション | 回転駆動装置およびそれを用いた遠心式ポンプ装置 |
| CN102720490B (zh) * | 2012-06-29 | 2014-11-26 | 西南石油大学 | 一种直井随钻钻井液油气信息测量方法及测量仪器 |
| CN102691498B (zh) * | 2012-06-29 | 2014-11-26 | 西南石油大学 | 一种水平井随钻泥浆电参数测量仪 |
| US20140221877A1 (en) * | 2013-02-01 | 2014-08-07 | Moshe Ein-Gal | Pressure-assisted irreversible electroporation |
| US10052420B2 (en) | 2013-04-30 | 2018-08-21 | Tc1 Llc | Heart beat identification and pump speed synchronization |
| US9623161B2 (en) | 2014-08-26 | 2017-04-18 | Tc1 Llc | Blood pump and method of suction detection |
| EP3256183B1 (en) | 2015-02-11 | 2025-08-13 | Tc1 Llc | Heart beat identification and pump speed synchronization |
| US10371152B2 (en) | 2015-02-12 | 2019-08-06 | Tc1 Llc | Alternating pump gaps |
| WO2016130944A1 (en) | 2015-02-12 | 2016-08-18 | Thoratec Corporation | System and method for controlling the position of a levitated rotor |
| US10245361B2 (en) | 2015-02-13 | 2019-04-02 | Tc1 Llc | Impeller suspension mechanism for heart pump |
| US10117983B2 (en) | 2015-11-16 | 2018-11-06 | Tc1 Llc | Pressure/flow characteristic modification of a centrifugal pump in a ventricular assist device |
| US10835734B1 (en) | 2017-08-21 | 2020-11-17 | Wayne May | High and low impedance systems and methods for the generation and use of constant intensity electric fields |
| EP3666882A1 (en) | 2018-12-12 | 2020-06-17 | AIT Austrian Institute of Technology GmbH | Specific electroporation and lysis of eukaryotic cells |
| CN113281380B (zh) * | 2021-05-20 | 2024-06-11 | 重庆大学 | 一种摩擦纳米发电机驱动的电介质陷阱态测量和成像系统及方法 |
| ES2991715B2 (es) * | 2024-03-22 | 2025-06-27 | Gil Daniel Serrano | Electrodo con proteccion frente a arco electrico |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2919235A (en) * | 1956-11-06 | 1959-12-29 | Paul S Roller | Electrolytic method and apparatus for the production of metal hydroxide |
| GB8621948D0 (en) * | 1986-09-11 | 1986-10-15 | Gibbs R W | Destroying bacteria |
| US4822470A (en) * | 1987-10-09 | 1989-04-18 | Baylor College Of Medicine | Method of and apparatus for cell poration and cell fusion using radiofrequency electrical pulses |
| US5134070A (en) * | 1990-06-04 | 1992-07-28 | Casnig Dael R | Method and device for cell cultivation on electrodes |
| US5234555A (en) * | 1991-02-05 | 1993-08-10 | Ibbott Jack Kenneth | Method and apparatus for ionizing fluids utilizing a capacitive effect |
| US5983131A (en) * | 1995-08-11 | 1999-11-09 | Massachusetts Institute Of Technology | Apparatus and method for electroporation of tissue |
| US5690978A (en) * | 1996-09-30 | 1997-11-25 | Ohio State University | High voltage pulsed electric field treatment chambers for the preservation of liquid food products |
| US6090617A (en) * | 1996-12-05 | 2000-07-18 | Entremed, Inc. | Flow electroporation chamber with electrodes having a crystalline metal nitride coating |
| GB9908681D0 (en) * | 1999-04-16 | 1999-06-09 | Central Research Lab Ltd | Apparatus for, and method of, introducing a substance into an object |
| US6455014B1 (en) * | 1999-05-14 | 2002-09-24 | Mesosystems Technology, Inc. | Decontamination of fluids or objects contaminated with chemical or biological agents using a distributed plasma reactor |
| US6689380B1 (en) * | 1999-05-17 | 2004-02-10 | Kevin S. Marchitto | Remote and local controlled delivery of pharmaceutical compounds using electromagnetic energy |
| CA2376368C (en) * | 1999-06-08 | 2009-08-11 | Altea Technologies, Inc. | Apparatus for microporation of biological membranes using thin film tissue interface devices, and method therefor |
| US6300108B1 (en) * | 1999-07-21 | 2001-10-09 | The Regents Of The University Of California | Controlled electroporation and mass transfer across cell membranes |
| US7192553B2 (en) * | 1999-12-15 | 2007-03-20 | Plasmasol Corporation | In situ sterilization and decontamination system using a non-thermal plasma discharge |
| GB9930718D0 (en) * | 1999-12-24 | 2000-02-16 | Central Research Lab Ltd | Apparatus for and method of making electrical measurements on objects |
| AU2001228841A1 (en) * | 2000-01-27 | 2001-08-07 | The Mollennium Laboratories | Molecule transferring device, auxiliary for molecule transferring device, and molecule transferring method |
| US6868289B2 (en) * | 2002-10-02 | 2005-03-15 | Standen Ltd. | Apparatus for treating a tumor or the like and articles incorporating the apparatus for treatment of the tumor |
| US6928318B2 (en) | 2000-05-22 | 2005-08-09 | Merck & Co., Inc. | System and method for assessing the performance of a pharmaceutical agent delivery system |
| US6911225B2 (en) * | 2001-05-07 | 2005-06-28 | Regents Of The University Of Minnesota | Method and apparatus for non-thermal pasteurization of living-mammal-instillable liquids |
| US6562386B2 (en) | 2001-05-07 | 2003-05-13 | Regents Of The University Of Minnesota | Method and apparatus for non-thermal pasteurization |
| US7011790B2 (en) * | 2001-05-07 | 2006-03-14 | Regents Of The University Of Minnesota | Non-thermal disinfection of biological fluids using non-thermal plasma |
| KR20040077658A (ko) | 2001-11-02 | 2004-09-06 | 플라스마솔 코포레이션 | 플라스마 방전 및 필터를 이용한 살균 및 오염제거 시스템 |
| ATE412447T1 (de) | 2002-05-23 | 2008-11-15 | Gendel Ltd | Ablationsvorrichtung |
| RU26004U1 (ru) * | 2002-05-29 | 2002-11-10 | Общество с ограниченной ответственностью Центр по изготовлению медицинской техники "Экстратерм" | Устройство для высокочастотной терапии и система ориентации электродов для него |
| JP2004202086A (ja) | 2002-12-26 | 2004-07-22 | Teikoku Seiyaku Co Ltd | エレクトロポレーション用薬物投与部、エレクトロポレーション用薬物投与システム、及びエレクトロポレーション用薬物投与方法 |
| JP4037258B2 (ja) * | 2002-12-26 | 2008-01-23 | 株式会社吉野工業所 | 櫛付き容器 |
| JP2004248653A (ja) | 2003-02-22 | 2004-09-09 | Minoru Seki | 流通型エレクトロポレーション用電極装置およびそれを用いた細胞への物質導入方法 |
| JP4319427B2 (ja) * | 2003-02-28 | 2009-08-26 | 株式会社東芝 | 医用超音波照射装置 |
| WO2007021994A2 (en) | 2005-08-12 | 2007-02-22 | Maxcyte, Inc. | Electrode shielding for electroporation |
| CA2678450A1 (en) * | 2007-03-01 | 2008-09-04 | Queen's University At Kingston | Planar electroporation apparatus and method |
-
2006
- 2006-10-20 US US11/551,584 patent/US8226811B2/en not_active Expired - Fee Related
- 2006-10-31 NZ NZ603542A patent/NZ603542A/xx not_active IP Right Cessation
- 2006-10-31 CA CA2628407A patent/CA2628407C/en not_active Expired - Fee Related
- 2006-10-31 BR BRPI0618420-0A patent/BRPI0618420A2/pt not_active IP Right Cessation
- 2006-10-31 EP EP06827315.0A patent/EP1952133B1/en not_active Not-in-force
- 2006-10-31 WO PCT/US2006/042712 patent/WO2007056027A1/en not_active Ceased
- 2006-10-31 RU RU2008121962/28A patent/RU2408006C2/ru not_active IP Right Cessation
- 2006-10-31 UA UAA200807394A patent/UA95262C2/uk unknown
- 2006-10-31 KR KR1020087013250A patent/KR101361498B1/ko not_active Expired - Fee Related
- 2006-10-31 JP JP2008539011A patent/JP5607304B2/ja not_active Expired - Fee Related
- 2006-10-31 AU AU2006311979A patent/AU2006311979B2/en not_active Ceased
-
2010
- 2010-04-29 US US12/769,872 patent/US8221596B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR101361498B1 (ko) | 2014-02-12 |
| WO2007056027A1 (en) | 2007-05-18 |
| US8221596B2 (en) | 2012-07-17 |
| CA2628407C (en) | 2014-08-05 |
| EP1952133B1 (en) | 2016-03-30 |
| US20070095648A1 (en) | 2007-05-03 |
| JP2009515168A (ja) | 2009-04-09 |
| RU2008121962A (ru) | 2009-12-10 |
| AU2006311979A1 (en) | 2007-05-18 |
| CA2628407A1 (en) | 2007-05-18 |
| US8226811B2 (en) | 2012-07-24 |
| AU2006311979B2 (en) | 2013-01-24 |
| UA95262C2 (uk) | 2011-07-25 |
| JP5607304B2 (ja) | 2014-10-15 |
| RU2408006C2 (ru) | 2010-12-27 |
| NZ603542A (en) | 2013-03-28 |
| EP1952133A4 (en) | 2011-08-31 |
| US20110139608A1 (en) | 2011-06-16 |
| EP1952133A1 (en) | 2008-08-06 |
| KR20080080518A (ko) | 2008-09-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US8221596B2 (en) | High impedance system for generating electric fields | |
| US10982182B2 (en) | Flow electroporation device | |
| Napotnik et al. | In vitro electroporation detection methods–An overview | |
| JP2009515168A5 (enExample) | ||
| US20090198231A1 (en) | Methods to treat unwanted tissue with electric pulses | |
| CN101233237A (zh) | 跨组织细胞膜的受控电穿孔和传质 | |
| Milestone et al. | Modeling coupled single cell electroporation and thermal effects from nanosecond electric pulse trains | |
| CN103865794B (zh) | 一种手持电穿孔装置 | |
| JPH01158342A (ja) | マイクロカラムによる動電分離用のオンカラム式電導度検出器 | |
| CN106676001B (zh) | 基于交叉窄通道可选择性持续流的细胞电穿孔系统及方法 | |
| Yao et al. | Nanosecond pulses targeting intracellular ablation increase destruction of tumor cells with irregular morphology | |
| CN103937669B (zh) | 一种手持电穿孔装置 | |
| CN110115803A (zh) | 一种可用于生物医学研究的电源装置及配套电极阵列设计 | |
| US10835734B1 (en) | High and low impedance systems and methods for the generation and use of constant intensity electric fields | |
| CN101331392B (zh) | 用于产生电场的高阻抗系统及所使用的方法 | |
| DK2528460T3 (en) | Devices and method for the treatment of high voltage pulse in ring spalte | |
| MX2008005673A (es) | Sistema de alta impedancia que genera campos electricos y metodo de uso | |
| Dalmay et al. | A microfluidic device with removable packaging for the real time visualisation of intracellular effects of nanosecond electrical pulses on adherent cells | |
| US20200070163A1 (en) | Method and device for high field strength electrotransfection of microvescicles and cells | |
| Murauskas et al. | Electroporation cuvette with integrated electrodes for high gradient electric field generation | |
| Priya et al. | Modeling of electroporation and electric field investigation for a single cell dispersed in liquid foods | |
| Arslan et al. | Finite element analysis of electric field for in-vitro electropermeabilization | |
| Joshi | Simulations of Membrane Effects of Cells After Exposure to Ultrashort Pulses | |
| Kabir Ahamed | Optimization of irreversible electroporation technique for the study of pore formation in lipid membranes of giant unilamellar vesicles | |
| Kohli et al. | Impedance of goat eye lens at different DC voltages |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06G | Technical and formal requirements: other requirements [chapter 6.7 patent gazette] |
Free format text: SOLICITA-SE A REGULARIZACAO DA PROCURACAO, UMA VEZ QUE BASEADO NO ARTIGO 216 1O DA LPI, O DOCUMENTO DE PROCURACAO DEVE SER APRESENTADO NO ORIGINAL, TRASLADO OU FOTOCOPIA AUTENTICADA. |
|
| B06G | Technical and formal requirements: other requirements [chapter 6.7 patent gazette] |
Free format text: SOLICITA-SE AO DEPOSITANTE QUE ESCLARECA DIVERGENCIA ENTRE O TITULO APRESENTADO NA PRIMEIRA PAGINA DO RELATORIO DESCRITIVO ("SISTEMA DE ALTA IMPEDANCIA PARA GERACAO DE CAMPOS ELETRICOS E METODO DE USO") E O TITULO APRESENTADO NA PAGINA DE RESUMO ("SISTEMA DE ALTA IMPEDANCIA PARA GERACAO DE CAMPOS ELETRICOS"). |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2435 DE 05-09-2017 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |