CA2628005A1 - Oral antimicrobial pharmaceutical compositions - Google Patents

Oral antimicrobial pharmaceutical compositions Download PDF

Info

Publication number
CA2628005A1
CA2628005A1 CA002628005A CA2628005A CA2628005A1 CA 2628005 A1 CA2628005 A1 CA 2628005A1 CA 002628005 A CA002628005 A CA 002628005A CA 2628005 A CA2628005 A CA 2628005A CA 2628005 A1 CA2628005 A1 CA 2628005A1
Authority
CA
Canada
Prior art keywords
pharmaceutical compositions
compositions according
matrix
treatment
colon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002628005A
Other languages
English (en)
French (fr)
Inventor
Mauro Aiani
Roberta Bozzella
Giuseppe Celasco
Roberto Villa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cosmo Technologies Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2628005A1 publication Critical patent/CA2628005A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A61K9/2826—Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA002628005A 2004-06-25 2005-05-03 Oral antimicrobial pharmaceutical compositions Abandoned CA2628005A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT001295A ITMI20041295A1 (it) 2004-06-25 2004-06-25 Composizioni farmaceutiche antimicrobiche orali
ITMI2004A001295 2004-06-25
CA2569683A CA2569683C (en) 2004-06-25 2005-05-03 Oral antimicrobial pharmaceutical compositions

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2569683A Division CA2569683C (en) 2004-06-25 2005-05-03 Oral antimicrobial pharmaceutical compositions

Publications (1)

Publication Number Publication Date
CA2628005A1 true CA2628005A1 (en) 2006-01-12

Family

ID=34968899

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2569683A Expired - Lifetime CA2569683C (en) 2004-06-25 2005-05-03 Oral antimicrobial pharmaceutical compositions
CA002628005A Abandoned CA2628005A1 (en) 2004-06-25 2005-05-03 Oral antimicrobial pharmaceutical compositions

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA2569683A Expired - Lifetime CA2569683C (en) 2004-06-25 2005-05-03 Oral antimicrobial pharmaceutical compositions

Country Status (22)

Country Link
US (9) US8486446B2 (enExample)
EP (2) EP1763339B1 (enExample)
JP (2) JP5026262B2 (enExample)
KR (2) KR101157486B1 (enExample)
CN (2) CN101317826A (enExample)
AT (1) ATE392889T1 (enExample)
CA (2) CA2569683C (enExample)
CY (1) CY1108196T1 (enExample)
DE (1) DE602005006278T2 (enExample)
DK (1) DK1763339T3 (enExample)
ES (1) ES2303255T3 (enExample)
FI (1) FIC20190031I1 (enExample)
HR (1) HRP20080252T3 (enExample)
HU (1) HUS1900037I1 (enExample)
IT (1) ITMI20041295A1 (enExample)
MX (1) MXPA06014698A (enExample)
PL (1) PL1763339T3 (enExample)
PT (1) PT1763339E (enExample)
RS (1) RS50581B (enExample)
SI (1) SI1763339T1 (enExample)
WO (1) WO2006003043A1 (enExample)
ZA (1) ZA200610577B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
ES2905795T3 (es) † 2007-07-06 2022-04-12 Lupin Ltd Composiciones farmacéuticas de rifaximina
WO2009037264A2 (en) * 2007-09-17 2009-03-26 Da Volterra Colonic delivery of antimicrobial agents
EP2376077B1 (en) 2009-01-12 2017-03-15 Biokier Inc. Composition and method for treatment of diabetes
US9314444B2 (en) 2009-01-12 2016-04-19 Biokier, Inc. Composition and method for treatment of NASH
US9006288B2 (en) 2009-01-12 2015-04-14 Biokier, Inc. Composition and method for treatment of diabetes
WO2010144865A2 (en) 2009-06-12 2010-12-16 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
AU2010298303A1 (en) 2009-09-23 2012-04-12 Biokier, Inc. Composition and method for treatment of diabetes
WO2012016707A2 (en) * 2010-08-06 2012-02-09 Ratiopharm Gmbh Oral dosage form for the modified release of dimebolin
WO2012075015A2 (en) * 2010-11-29 2012-06-07 Dr. Reddy's Laboratories Ltd. Oral metronidazole pharmaceutical compositions
BR112020009171A2 (pt) * 2017-11-10 2020-11-03 Cosmo Technologies Ltd. composições orais de rifamicina sv
IT202000005782A1 (it) 2020-03-18 2021-09-18 Dpl Pharma S P A Formulazioni farmaceutiche a rilascio controllato per il trattamento di infezioni intestinali
KR102714380B1 (ko) * 2021-06-09 2024-10-11 강원대학교산학협력단 경구 투여용 나노입자 및 이의 제조방법

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE458505B (sv) * 1979-07-10 1989-04-10 Lepetit Spa Anvaendningen av rifamycin sv och salter daerav foer framstaellning av en beredning foer behandling av reumatoid artrit samt vissa av salterna och deras framstaellning
US4409209A (en) * 1979-10-12 1983-10-11 Ciba-Geigy Corporation Novel phosphorylmuramyl peptides and processes for the manufacture thereof
IT1230576B (it) * 1988-10-20 1991-10-28 Angeli Inst Spa Formulazioni farmaceutiche per via orale a liberazione selettiva nel colon
IE61651B1 (en) 1990-07-04 1994-11-16 Zambon Spa Programmed release oral solid pharmaceutical dosage form
IT1260505B (it) 1992-06-01 1996-04-09 Poli Ind Chimica Spa Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon
CN1097306A (zh) * 1993-07-12 1995-01-18 中国医科大学第二临床学院 复方抗炎栓剂
US5849327A (en) * 1994-07-29 1998-12-15 Advanced Polymer Systems, Inc. Delivery of drugs to the lower gastrointestinal tract
US6861053B1 (en) 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
US6245351B1 (en) * 1996-03-07 2001-06-12 Takeda Chemical Industries, Ltd. Controlled-release composition
US5985823A (en) * 1997-06-09 1999-11-16 Ambi Inc. Method for the treatment of diarrheal disease and for eliminating particular bacterial populations from the colon
JP2000514101A (ja) * 1997-07-01 2000-10-24 ファイザー・インク セルトラリン塩及びセルトラリンの持続性剤形
DE19850445A1 (de) 1998-11-02 2000-05-04 Falk Pharma Gmbh Arzneimittel zur topischen Behandlung entzündlicher Darmerkrankungen
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
GB9910773D0 (en) 1999-05-11 1999-07-07 West Pharm Serv Drug Res Ltd Novel single unit coated dosage forms that can be used to minimise the effect of food on the absorption of drugs from the gastrointestinal tract
HK1046244B (zh) * 1999-06-14 2005-06-03 科斯默技术有限公司 控制释放与掩蔽味道的口服药物组合物
JP4393098B2 (ja) 2002-06-21 2010-01-06 独立行政法人科学技術振興機構 アンサマイシン系抗生物質の新規用途及び新規血管新生抑制物質のスクリーニング方法
CN1201736C (zh) * 2002-07-19 2005-05-18 安徽省药物研究所 甲硝唑结肠定位缓释制剂
CN1678309A (zh) 2002-08-26 2005-10-05 S.L.A.制药有限公司 白凡士林中包含至少5%甲硝哒唑的局部用配方及其在肛门与直肠区的用途
WO2005030173A1 (en) 2003-09-25 2005-04-07 Ranbaxy Laboratories Limited Colon-specific drug delivery using interpolymer complexations

Also Published As

Publication number Publication date
EP1763339B1 (en) 2008-04-23
PL1763339T3 (pl) 2008-10-31
US20070248664A1 (en) 2007-10-25
EP1894560A1 (en) 2008-03-05
WO2006003043A1 (en) 2006-01-12
US20120207834A1 (en) 2012-08-16
EP1763339A1 (en) 2007-03-21
ZA200610577B (en) 2008-07-30
DK1763339T3 (da) 2008-08-11
US8741948B2 (en) 2014-06-03
US20210093576A1 (en) 2021-04-01
US8263120B2 (en) 2012-09-11
US20120316228A1 (en) 2012-12-13
CY1108196T1 (el) 2014-02-12
CA2569683A1 (en) 2006-01-12
US20120316229A1 (en) 2012-12-13
KR20070028441A (ko) 2007-03-12
CA2569683C (en) 2012-04-03
HRP20080252T3 (hr) 2008-07-31
JP5026262B2 (ja) 2012-09-12
US20130004569A1 (en) 2013-01-03
HUS1900037I1 (hu) 2019-07-29
RS50581B (sr) 2010-05-07
MXPA06014698A (es) 2007-03-26
SI1763339T1 (sl) 2008-08-31
US8486446B2 (en) 2013-07-16
CN1976685B (zh) 2011-05-18
JP2008163038A (ja) 2008-07-17
US20140370093A1 (en) 2014-12-18
KR20080059337A (ko) 2008-06-26
CN1976685A (zh) 2007-06-06
ES2303255T3 (es) 2008-08-01
JP2008503540A (ja) 2008-02-07
FIC20190031I1 (fi) 2019-05-28
DE602005006278D1 (de) 2008-06-05
US8529945B2 (en) 2013-09-10
CN101317826A (zh) 2008-12-10
ATE392889T1 (de) 2008-05-15
KR101157486B1 (ko) 2012-07-09
ITMI20041295A1 (it) 2004-09-25
US20080233193A1 (en) 2008-09-25
PT1763339E (pt) 2008-06-19
DE602005006278T2 (de) 2009-10-08
US20190192441A1 (en) 2019-06-27

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Legal Events

Date Code Title Description
FZDE Discontinued