CA2619663A1 - Human ribosomal dna(rdna) and ribosomal rna (rrna) nucleic acids and uses thereof - Google Patents
Human ribosomal dna(rdna) and ribosomal rna (rrna) nucleic acids and uses thereof Download PDFInfo
- Publication number
- CA2619663A1 CA2619663A1 CA002619663A CA2619663A CA2619663A1 CA 2619663 A1 CA2619663 A1 CA 2619663A1 CA 002619663 A CA002619663 A CA 002619663A CA 2619663 A CA2619663 A CA 2619663A CA 2619663 A1 CA2619663 A1 CA 2619663A1
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- Prior art keywords
- nucleic acid
- nucleotide sequence
- rrna
- molecule
- rna
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/351—Conjugate
- C12N2310/3511—Conjugate intercalating or cleaving agent
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (15)
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| US70959805P | 2005-08-19 | 2005-08-19 | |
| US60/709,598 | 2005-08-19 | ||
| US73246005P | 2005-11-01 | 2005-11-01 | |
| US60/732,460 | 2005-11-01 | ||
| US75159305P | 2005-12-19 | 2005-12-19 | |
| US60/751,593 | 2005-12-19 | ||
| US77592406P | 2006-02-22 | 2006-02-22 | |
| US60/775,924 | 2006-02-22 | ||
| US77932706P | 2006-03-02 | 2006-03-02 | |
| US60/779,327 | 2006-03-02 | ||
| US78380106P | 2006-03-16 | 2006-03-16 | |
| US60/783,801 | 2006-03-16 | ||
| US78910906P | 2006-04-03 | 2006-04-03 | |
| US60/789,109 | 2006-04-03 | ||
| PCT/US2006/032508 WO2007022474A2 (en) | 2005-08-19 | 2006-08-18 | HUMAN RIBOSOMAL DNA(rDNA) AND RIBOSOMAL RNA (rRNA) NUCLEIC ACIDS AND USES THEREOF |
Publications (1)
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|---|---|
| CA2619663A1 true CA2619663A1 (en) | 2007-02-22 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002619663A Abandoned CA2619663A1 (en) | 2005-08-19 | 2006-08-18 | Human ribosomal dna(rdna) and ribosomal rna (rrna) nucleic acids and uses thereof |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20070117770A1 (enExample) |
| EP (1) | EP1926372A2 (enExample) |
| JP (1) | JP2009504192A (enExample) |
| CA (1) | CA2619663A1 (enExample) |
| WO (1) | WO2007022474A2 (enExample) |
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| WO2008060693A2 (en) * | 2006-05-17 | 2008-05-22 | Cylene Pharmaceuticals, Inc. | Tetracyclic imidazole analogs |
| US8278057B2 (en) * | 2007-09-14 | 2012-10-02 | Nestec S.A. | Addressable antibody arrays and methods of use |
| KR101682867B1 (ko) * | 2007-10-05 | 2016-12-05 | 센화 바이오사이언시즈 인코포레이티드 | 퀴놀론 유사체 및 이와 관련된 방법 |
| JP2011520111A (ja) * | 2008-05-09 | 2011-07-14 | リュー，ジーピン | 分子検出システム |
| US9115407B2 (en) | 2008-12-10 | 2015-08-25 | University Of Washington | Ratiometric pre-rRNA analysis |
| SG175779A1 (en) * | 2009-05-15 | 2011-12-29 | Boehringer Ingelheim Int | Improved cell lines having reduced expression of nocr and use thereof |
| KR100998365B1 (ko) * | 2009-06-29 | 2010-12-06 | 압타바이오 주식회사 | 치료 효능이 있는 변형핵산 및 구아노신을 함유하는 올리고뉴클레오티드 변형체 |
| CN103533934B (zh) * | 2011-03-17 | 2016-03-30 | 特尔汗什莫尔医学基础设施研究和服务公司 | 用于治疗自身免疫性疾病的喹诺酮类似物 |
| CA2925698C (en) | 2013-11-28 | 2021-11-09 | Tel Hashomer Medical Research Infrastructure And Services Ltd. | Rna polymerase i inhibitors and uses thereof |
| KR20180113976A (ko) | 2015-11-20 | 2018-10-17 | 센화 바이오사이언시즈 인코포레이티드 | 암을 치료하기 위한 테트라사이클릭 퀴놀론 유사체의 병행 요법 |
| US9957282B2 (en) | 2015-12-14 | 2018-05-01 | Senhwa Biosciences, Inc. | Crystalline forms of quinolone analogs and their salts |
| KR20180111797A (ko) * | 2015-12-14 | 2018-10-11 | 센화 바이오사이언시즈 인코포레이티드 | 퀴놀론 유사체의 결정형 및 그것의 염 |
| AU2017257189B2 (en) | 2016-04-29 | 2022-03-31 | Icahn School Of Medicine At Mount Sinai | Targeting the innate immune system to induce long-term tolerance and to resolve macrophage accumulation in atherosclerosis |
| RU2020130050A (ru) | 2018-02-15 | 2022-03-15 | Сэньхва Байосайенсиз, Инк. | Аналоги хинолонов и их соли, композиции и способ их применения |
| WO2022198101A1 (en) | 2021-03-19 | 2022-09-22 | Trained Therapeutix Discovery, Inc. | Compounds for regulating trained immunity, and their methods of use |
| CN118562793A (zh) * | 2021-08-23 | 2024-08-30 | 北京嘉树佳业科技有限公司 | 来源于药用植物的sRNA及其应用 |
| WO2025114459A1 (en) * | 2023-11-28 | 2025-06-05 | Genome Therapeutics Ltd | Tetracyclic compounds for use in antibody-drug conjugates for the treatment of cancer |
Family Cites Families (20)
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| US5601984A (en) * | 1983-01-10 | 1997-02-11 | Gen-Probe Incorporated | Method for detecting, the presense or amount of a taxonomic group of organisms using specific R-RNA subsequences as probes |
| US5723597A (en) * | 1983-01-10 | 1998-03-03 | Gen-Probe Incorporated | Ribosomal nucleic acid probes for detecting organisms or groups of organisms |
| US5681698A (en) * | 1991-04-25 | 1997-10-28 | Gen-Probe Incorporated | 23S rRNA nucleic acid probes to mycobacterium kansasii |
| DK0787726T3 (da) * | 1994-06-14 | 2002-02-11 | Dainippon Pharmaceutical Co | Ny forbindelse, fremgangsmåde til fremstilling deraf og antitumor-middel |
| US20050191661A1 (en) * | 1996-11-06 | 2005-09-01 | Tetsuya Gatanaga | Treatment of inflammatory disease by cleaving TNF receptors |
| KR100533531B1 (ko) * | 1996-11-06 | 2005-12-06 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 분리된 종양괴사인자 수용체 방출효소, 그 효소로 이루어지는 조성물 및 그것의 사용방법 |
| US6593456B1 (en) * | 1996-11-06 | 2003-07-15 | The Regents Of The University Of California | Tumor necrosis factor receptor releasing enzyme |
| US6930084B1 (en) * | 1996-11-06 | 2005-08-16 | The Regents Of The University Of California | Treating arthritis with TNF receptor releasing enzyme |
| US7138384B1 (en) * | 1997-08-29 | 2006-11-21 | The Regents Of The University Of California | Modulators of DNA cytosine-5 methyltransferase and methods for use thereof |
| AU2657499A (en) * | 1998-02-04 | 1999-08-23 | Board Of Regents, The University Of Texas System | Synthesis of quinobenzoxazine analogues with topoisomerase ii and quadruplex interactions for use as antineoplastic agents |
| US6911314B2 (en) * | 1999-05-14 | 2005-06-28 | The Regents Of The University Of California | Screening for drugs that affect TNF receptor releasing enzyme |
| US20030204075A9 (en) * | 1999-08-09 | 2003-10-30 | The Snp Consortium | Identification and mapping of single nucleotide polymorphisms in the human genome |
| US20020076721A1 (en) * | 2000-08-07 | 2002-06-20 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of pancreatic cancer |
| US20030166213A1 (en) * | 2000-12-15 | 2003-09-04 | Greenspan Ralph J. | Methods for identifying compounds that modulate disorders related to nitric oxide/ cGMP-dependent protein kinase signaling |
| US6645749B2 (en) * | 2001-05-25 | 2003-11-11 | Novozymes A/S | Lipolytic enzyme |
| AU2003226304A1 (en) * | 2002-04-05 | 2003-10-27 | Cylene Pharmaceuticals, Inc. | Methods for targeting quadruplex dna |
| WO2004024091A2 (en) * | 2002-09-12 | 2004-03-25 | Cyternex, Inc. | Expanded porphyrin compositions for tumor inhibition |
| US7354916B2 (en) * | 2003-04-07 | 2008-04-08 | Cylene Pharmaceuticals | Substituted quinobenzoxazine analogs |
| US20040115706A1 (en) * | 2003-09-11 | 2004-06-17 | Jin Cheng He | High-throughput methods for identifying quadruplex forming nucleic acids and modulators thereof |
| DK1725233T3 (da) * | 2004-03-15 | 2011-03-14 | Sunesis Pharmaceuticals Inc | Farmaceutisk sammensætning omfattende SNS-595 og anvendelse deraf |
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2006
- 2006-08-18 CA CA002619663A patent/CA2619663A1/en not_active Abandoned
- 2006-08-18 WO PCT/US2006/032508 patent/WO2007022474A2/en not_active Ceased
- 2006-08-18 US US11/506,588 patent/US20070117770A1/en not_active Abandoned
- 2006-08-18 EP EP06801941A patent/EP1926372A2/en not_active Withdrawn
- 2006-08-18 JP JP2008527196A patent/JP2009504192A/ja active Pending
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2008
- 2008-02-04 US US12/025,705 patent/US20090181377A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1926372A2 (en) | 2008-06-04 |
| WO2007022474A2 (en) | 2007-02-22 |
| WO2007022474A3 (en) | 2007-12-21 |
| US20070117770A1 (en) | 2007-05-24 |
| US20090181377A1 (en) | 2009-07-16 |
| JP2009504192A (ja) | 2009-02-05 |
| WO2007022474B1 (en) | 2008-02-14 |
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| Date | Code | Title | Description |
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| FZDE | Discontinued |