CA2619663A1 - Human ribosomal dna(rdna) and ribosomal rna (rrna) nucleic acids and uses thereof - Google Patents
Human ribosomal dna(rdna) and ribosomal rna (rrna) nucleic acids and uses thereof Download PDFInfo
- Publication number
- CA2619663A1 CA2619663A1 CA002619663A CA2619663A CA2619663A1 CA 2619663 A1 CA2619663 A1 CA 2619663A1 CA 002619663 A CA002619663 A CA 002619663A CA 2619663 A CA2619663 A CA 2619663A CA 2619663 A1 CA2619663 A1 CA 2619663A1
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- Prior art keywords
- nucleic acid
- nucleotide sequence
- rrna
- molecule
- rna
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/351—Conjugate
- C12N2310/3511—Conjugate intercalating or cleaving agent
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| US73246005P | 2005-11-01 | 2005-11-01 | |
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| US75159305P | 2005-12-19 | 2005-12-19 | |
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| US77592406P | 2006-02-22 | 2006-02-22 | |
| US60/775,924 | 2006-02-22 | ||
| US77932706P | 2006-03-02 | 2006-03-02 | |
| US60/779,327 | 2006-03-02 | ||
| US78380106P | 2006-03-16 | 2006-03-16 | |
| US60/783,801 | 2006-03-16 | ||
| US78910906P | 2006-04-03 | 2006-04-03 | |
| US60/789,109 | 2006-04-03 | ||
| PCT/US2006/032508 WO2007022474A2 (en) | 2005-08-19 | 2006-08-18 | HUMAN RIBOSOMAL DNA(rDNA) AND RIBOSOMAL RNA (rRNA) NUCLEIC ACIDS AND USES THEREOF |
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| CA2619663A1 true CA2619663A1 (en) | 2007-02-22 |
Family
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Family Applications (1)
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| CA002619663A Abandoned CA2619663A1 (en) | 2005-08-19 | 2006-08-18 | Human ribosomal dna(rdna) and ribosomal rna (rrna) nucleic acids and uses thereof |
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| US (2) | US20070117770A1 (enExample) |
| EP (1) | EP1926372A2 (enExample) |
| JP (1) | JP2009504192A (enExample) |
| CA (1) | CA2619663A1 (enExample) |
| WO (1) | WO2007022474A2 (enExample) |
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| EP2023720A4 (en) * | 2006-05-17 | 2009-06-10 | Cylene Pharmaceuticals Inc | TETRACYCLIC IMIDAZOLE ANALOGS |
| US8278057B2 (en) * | 2007-09-14 | 2012-10-02 | Nestec S.A. | Addressable antibody arrays and methods of use |
| PT2214491T (pt) | 2007-10-05 | 2016-10-25 | Senhwa Biosciences Inc | Análogos de quinolona e métodos com eles relacionados |
| CA2723076A1 (en) * | 2008-05-09 | 2009-11-12 | Zhiping Liu | A molecule detecting system |
| WO2010068802A1 (en) * | 2008-12-10 | 2010-06-17 | University Of Washington | RATIOMETRIC PRE-rRNA ANALYSIS |
| CN102414320A (zh) * | 2009-05-15 | 2012-04-11 | 贝林格尔.英格海姆国际有限公司 | 具有降低的nocr表达的改良细胞系及其用途 |
| KR100998365B1 (ko) * | 2009-06-29 | 2010-12-06 | 압타바이오 주식회사 | 치료 효능이 있는 변형핵산 및 구아노신을 함유하는 올리고뉴클레오티드 변형체 |
| CN103533934B (zh) * | 2011-03-17 | 2016-03-30 | 特尔汗什莫尔医学基础设施研究和服务公司 | 用于治疗自身免疫性疾病的喹诺酮类似物 |
| ES2754207T3 (es) | 2013-11-28 | 2020-04-16 | Tel Hashomer Medical Res Infrastructure & Services Ltd | Inhibidores de la ARN polimerasa I y usos de los mismos |
| CN108601789A (zh) | 2015-11-20 | 2018-09-28 | 生华生物科技股份有限公司 | 用于治疗癌症的四环喹诺酮类似物组合疗法 |
| CN108699083A (zh) * | 2015-12-14 | 2018-10-23 | 生华生物科技股份有限公司 | 喹啉酮类似物及其盐的结晶形式 |
| US9957282B2 (en) | 2015-12-14 | 2018-05-01 | Senhwa Biosciences, Inc. | Crystalline forms of quinolone analogs and their salts |
| ES2913073T3 (es) | 2016-04-29 | 2022-05-31 | Icahn School Med Mount Sinai | Direccionamiento del sistema inmunitario innato para inducir tolerancia a largo plazo y resolver la acumulación de macrófagos en aterosclerosis |
| AU2019227294B2 (en) | 2018-02-15 | 2023-06-15 | Senhwa Biosciences, Inc. | Quinolone analogs and their salts, compositions, and method for their use |
| BR112023018950A2 (pt) | 2021-03-19 | 2024-02-27 | Icahn School Med Mount Sinai | Composto, composições nanobiológica e farmacêutica, métodos para tratar um distúrbio de proliferação celular, para tratar sepse e para ativar um receptor nod2, processo para fabricação de uma composição nanobiológica e kit |
| WO2023025161A1 (zh) * | 2021-08-23 | 2023-03-02 | 北京嘉树佳业科技有限公司 | 来源于药用植物的sRNA及其应用 |
| WO2025114459A1 (en) * | 2023-11-28 | 2025-06-05 | Genome Therapeutics Ltd | Tetracyclic compounds for use in antibody-drug conjugates for the treatment of cancer |
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| US5723597A (en) * | 1983-01-10 | 1998-03-03 | Gen-Probe Incorporated | Ribosomal nucleic acid probes for detecting organisms or groups of organisms |
| US5567587A (en) * | 1983-01-10 | 1996-10-22 | Gen-Probe Incorporated | Method for detecting, the presence and amount of prokaryotic organisms using specific rRNA subsequences as probes |
| US5681698A (en) * | 1991-04-25 | 1997-10-28 | Gen-Probe Incorporated | 23S rRNA nucleic acid probes to mycobacterium kansasii |
| CN1053668C (zh) * | 1994-06-14 | 2000-06-21 | 大日本制药株式会社 | 新型化合物及其制法和抗肿瘤剂 |
| US6930084B1 (en) * | 1996-11-06 | 2005-08-16 | The Regents Of The University Of California | Treating arthritis with TNF receptor releasing enzyme |
| US6593456B1 (en) * | 1996-11-06 | 2003-07-15 | The Regents Of The University Of California | Tumor necrosis factor receptor releasing enzyme |
| KR100533531B1 (ko) * | 1996-11-06 | 2005-12-06 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 분리된 종양괴사인자 수용체 방출효소, 그 효소로 이루어지는 조성물 및 그것의 사용방법 |
| US20050191661A1 (en) * | 1996-11-06 | 2005-09-01 | Tetsuya Gatanaga | Treatment of inflammatory disease by cleaving TNF receptors |
| US7138384B1 (en) * | 1997-08-29 | 2006-11-21 | The Regents Of The University Of California | Modulators of DNA cytosine-5 methyltransferase and methods for use thereof |
| US6528517B1 (en) * | 1998-02-04 | 2003-03-04 | Board Of Regents, The University Of Texas System | Synthesis of quinobenzoxazine analogues with topoisomerase II and quadruplex interactions for use as antineoplastic agents |
| US6911314B2 (en) * | 1999-05-14 | 2005-06-28 | The Regents Of The University Of California | Screening for drugs that affect TNF receptor releasing enzyme |
| US20030204075A9 (en) * | 1999-08-09 | 2003-10-30 | The Snp Consortium | Identification and mapping of single nucleotide polymorphisms in the human genome |
| WO2002012331A2 (en) * | 2000-08-07 | 2002-02-14 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of pancreatic cancer |
| US20030166213A1 (en) * | 2000-12-15 | 2003-09-04 | Greenspan Ralph J. | Methods for identifying compounds that modulate disorders related to nitric oxide/ cGMP-dependent protein kinase signaling |
| US6645749B2 (en) * | 2001-05-25 | 2003-11-11 | Novozymes A/S | Lipolytic enzyme |
| WO2003087317A2 (en) * | 2002-04-05 | 2003-10-23 | Cyternex, Inc. | Methods for targeting quadruplex dna |
| WO2004024091A2 (en) * | 2002-09-12 | 2004-03-25 | Cyternex, Inc. | Expanded porphyrin compositions for tumor inhibition |
| US7354916B2 (en) * | 2003-04-07 | 2008-04-08 | Cylene Pharmaceuticals | Substituted quinobenzoxazine analogs |
| US20040115706A1 (en) * | 2003-09-11 | 2004-06-17 | Jin Cheng He | High-throughput methods for identifying quadruplex forming nucleic acids and modulators thereof |
| WO2005089757A1 (en) * | 2004-03-15 | 2005-09-29 | Sunesis Pharmaceuticals, Inc. | Sns-595 and methods of using the same |
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- 2006-08-18 JP JP2008527196A patent/JP2009504192A/ja active Pending
- 2006-08-18 WO PCT/US2006/032508 patent/WO2007022474A2/en not_active Ceased
- 2006-08-18 CA CA002619663A patent/CA2619663A1/en not_active Abandoned
- 2006-08-18 EP EP06801941A patent/EP1926372A2/en not_active Withdrawn
- 2006-08-18 US US11/506,588 patent/US20070117770A1/en not_active Abandoned
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2008
- 2008-02-04 US US12/025,705 patent/US20090181377A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007022474B1 (en) | 2008-02-14 |
| US20070117770A1 (en) | 2007-05-24 |
| US20090181377A1 (en) | 2009-07-16 |
| WO2007022474A3 (en) | 2007-12-21 |
| WO2007022474A2 (en) | 2007-02-22 |
| EP1926372A2 (en) | 2008-06-04 |
| JP2009504192A (ja) | 2009-02-05 |
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