ATE403714T1 - Tumor necrosis factor rezeptor abspaltendes enzym,dessen zubereitungen und verwendungen - Google Patents

Tumor necrosis factor rezeptor abspaltendes enzym,dessen zubereitungen und verwendungen

Info

Publication number
ATE403714T1
ATE403714T1 AT97946457T AT97946457T ATE403714T1 AT E403714 T1 ATE403714 T1 AT E403714T1 AT 97946457 T AT97946457 T AT 97946457T AT 97946457 T AT97946457 T AT 97946457T AT E403714 T1 ATE403714 T1 AT E403714T1
Authority
AT
Austria
Prior art keywords
tnf
trre
preparations
necrosis factor
tumor necrosis
Prior art date
Application number
AT97946457T
Other languages
English (en)
Inventor
Gale Granger
Tetsuya Gatanaga
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of ATE403714T1 publication Critical patent/ATE403714T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/525—Tumor necrosis factor [TNF]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT97946457T 1996-11-06 1997-11-05 Tumor necrosis factor rezeptor abspaltendes enzym,dessen zubereitungen und verwendungen ATE403714T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3076196P 1996-11-06 1996-11-06

Publications (1)

Publication Number Publication Date
ATE403714T1 true ATE403714T1 (de) 2008-08-15

Family

ID=21855891

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97946457T ATE403714T1 (de) 1996-11-06 1997-11-05 Tumor necrosis factor rezeptor abspaltendes enzym,dessen zubereitungen und verwendungen

Country Status (14)

Country Link
US (3) US6569664B1 (de)
EP (1) EP0938548B1 (de)
JP (1) JP2001508648A (de)
KR (1) KR100533531B1 (de)
AT (1) ATE403714T1 (de)
AU (1) AU744873B2 (de)
BR (1) BR9712900A (de)
CA (1) CA2270898A1 (de)
DE (1) DE69738887D1 (de)
ID (1) ID22049A (de)
IL (1) IL129787A0 (de)
NO (1) NO992187L (de)
NZ (1) NZ335864A (de)
WO (1) WO1998020140A1 (de)

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US6930084B1 (en) 1996-11-06 2005-08-16 The Regents Of The University Of California Treating arthritis with TNF receptor releasing enzyme
EP0938548B1 (de) * 1996-11-06 2008-08-06 The Regents of the University of California Tumor necrosis factor rezeptor abspaltendes enzym, dessen zubereitungen und verwendungen
US6593456B1 (en) 1996-11-06 2003-07-15 The Regents Of The University Of California Tumor necrosis factor receptor releasing enzyme
US20050191661A1 (en) * 1996-11-06 2005-09-01 Tetsuya Gatanaga Treatment of inflammatory disease by cleaving TNF receptors
IL138798A0 (en) * 1998-04-07 2001-10-31 Medimmune Inc Vaccines and antibodies against bacterial pneumococcal infection
US6911314B2 (en) 1999-05-14 2005-06-28 The Regents Of The University Of California Screening for drugs that affect TNF receptor releasing enzyme
CA2399388A1 (en) * 2000-02-11 2001-08-16 Michael J. Lenardo Identification of a domain in the tumor necrosis factor receptor family that mediates pre-ligand receptor assembly and function
WO2001064856A2 (en) * 2000-02-28 2001-09-07 The Government Of The United States Of America, A S Represented By The Secretary, Department Of Hea Lth And Human Services Regulators of type-1 tumor necrosis factor receptor and other cytokine receptor shedding
GB0230203D0 (en) * 2002-12-27 2003-02-05 Domantis Ltd Fc fusion
JP5271480B2 (ja) * 2003-04-30 2013-08-21 味の素株式会社 体温低下抑制剤
EP1699478A2 (de) * 2003-09-23 2006-09-13 Meyer Pharmaceuticals, LLC Behandlung von entzündung mit einem biologischen mittel, das zur freisetzung von zytokin-rezeptoren aus zellen führt
WO2005087947A2 (en) * 2004-03-09 2005-09-22 Meyer Pharmaceuticals Llc Bioengineered proteolytic enzymes with enhanced specificity for cytokine receptors
GB0414054D0 (en) 2004-06-23 2004-07-28 Owen Mumford Ltd Improvements relating to automatic injection devices
CA2619663A1 (en) * 2005-08-19 2007-02-22 Cylene Pharmaceuticals, Inc. Human ribosomal dna(rdna) and ribosomal rna (rrna) nucleic acids and uses thereof
US8093017B2 (en) * 2005-12-07 2012-01-10 Siemens Heathcare Diagnostics Inc. Detection of soluble adiponectin receptor peptides and use in diagnostics and therapeutics
CN103316403B (zh) * 2006-06-30 2017-05-24 艾伯维生物技术有限公司 自动注射装置
EP2373957B1 (de) 2009-01-06 2020-04-01 Siemens Healthcare Diagnostics Inc. Verfahren zur bestimmung eines flüssigkeitsstandes in einem behälter durch bilderzeugung
EP2749305B1 (de) 2011-01-24 2017-11-01 AbbVie Biotechnology Ltd Automatische Injektionsvorrichtungen mit umspritzten Greifflächen

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US5192537A (en) 1984-03-30 1993-03-09 Cellcor Inc. Method of treating renal cell carcinoma using activated mononuclear cells, renal tumor antigen and cimetidine
US5643740A (en) 1983-02-24 1997-07-01 Ronald J. Billing Monoclonal antibody specific for activated lymphocytes and monocytes
US5001061A (en) * 1983-06-22 1991-03-19 Lubrizol Genetics, Inc. nifD promoter of Bradyrhizobium
DE3343530A1 (de) 1983-12-01 1985-06-13 Max Planck Gesellschaft Arzneimittel mit verbesserter penetration der gewebsmembran
JPH0611709B2 (ja) 1984-10-19 1994-02-16 チロン コーポレイション 角膜基質創傷の治療のための組成物
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Also Published As

Publication number Publication date
NZ335864A (en) 2001-09-28
AU744873B2 (en) 2002-03-07
DE69738887D1 (de) 2008-09-18
KR100533531B1 (ko) 2005-12-06
US20030170776A1 (en) 2003-09-11
EP0938548A1 (de) 1999-09-01
WO1998020140A1 (en) 1998-05-14
US6573062B1 (en) 2003-06-03
US6858402B2 (en) 2005-02-22
AU5162198A (en) 1998-05-29
NO992187D0 (no) 1999-05-05
IL129787A0 (en) 2000-02-29
ID22049A (id) 1999-08-26
BR9712900A (pt) 2000-11-28
JP2001508648A (ja) 2001-07-03
US6569664B1 (en) 2003-05-27
EP0938548B1 (de) 2008-08-06
CA2270898A1 (en) 1998-05-14
KR20000053073A (ko) 2000-08-25
NO992187L (no) 1999-07-01

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