CA2619250A1 - Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof - Google Patents

Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof Download PDF

Info

Publication number
CA2619250A1
CA2619250A1 CA002619250A CA2619250A CA2619250A1 CA 2619250 A1 CA2619250 A1 CA 2619250A1 CA 002619250 A CA002619250 A CA 002619250A CA 2619250 A CA2619250 A CA 2619250A CA 2619250 A1 CA2619250 A1 CA 2619250A1
Authority
CA
Canada
Prior art keywords
holes
platen
array
sample
hole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002619250A
Other languages
English (en)
French (fr)
Inventor
Robert Hess
John Linton
Tanya S. Kanigan
Colin Brenan
Can Ozbal
Daniel Horowitz
Sergey E. Ilyin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Life Technologies Corp
Original Assignee
Biotrove, Inc.
Robert Hess
John Linton
Tanya S. Kanigan
Colin Brenan
Can Ozbal
Daniel Horowitz
Sergey E. Ilyin
Biotrove Acquisition Corporation
Biotrove Corporation
Life Technologies Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotrove, Inc., Robert Hess, John Linton, Tanya S. Kanigan, Colin Brenan, Can Ozbal, Daniel Horowitz, Sergey E. Ilyin, Biotrove Acquisition Corporation, Biotrove Corporation, Life Technologies Corporation filed Critical Biotrove, Inc.
Publication of CA2619250A1 publication Critical patent/CA2619250A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B01L3/50255Multi-well filtration
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50857Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates using arrays or bundles of open capillaries for holding samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065Multiple transfer devices
    • G01N35/1074Multiple transfer devices arranged in a two-dimensional array
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409Sample holders or containers
    • H01J49/0418Sample holders or containers for laser desorption, e.g. matrix-assisted laser desorption/ionisation [MALDI] plates or surface enhanced laser desorption/ionisation [SELDI] plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0689Sealing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0819Microarrays; Biochips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/10Means to control humidity and/or other gases
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0442Moving fluids with specific forces or mechanical means specific forces thermal energy, e.g. vaporisation, bubble jet
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0241Drop counters; Drop formers
    • B01L3/0268Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0289Apparatus for withdrawing or distributing predetermined quantities of fluid
    • B01L3/0293Apparatus for withdrawing or distributing predetermined quantities of fluid for liquids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/38Flow patterns
    • G01N30/46Flow patterns using more than one column
    • G01N30/466Flow patterns using more than one column with separation columns in parallel
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/60Construction of the column
    • G01N30/6091Cartridges
CA002619250A 2005-08-11 2006-08-11 Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof Abandoned CA2619250A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70750105P 2005-08-11 2005-08-11
US60/707,501 2005-08-11
PCT/US2006/031534 WO2007022026A2 (en) 2005-08-11 2006-08-10 Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof

Publications (1)

Publication Number Publication Date
CA2619250A1 true CA2619250A1 (en) 2007-02-22

Family

ID=37758246

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002619250A Abandoned CA2619250A1 (en) 2005-08-11 2006-08-11 Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof

Country Status (5)

Country Link
EP (1) EP1920045A4 (ja)
JP (1) JP2009504161A (ja)
AU (1) AU2006279763A1 (ja)
CA (1) CA2619250A1 (ja)
WO (1) WO2007022026A2 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117630318A (zh) * 2024-01-23 2024-03-01 四川省科源工程技术测试中心有限责任公司 电泳法测定水环境有机物含量的设备及方法

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8357530B2 (en) * 2007-08-01 2013-01-22 National University Corporation Tokyo University Of Agriculture And Technology Microfluidic device for trapping single cell
JP5390540B2 (ja) * 2008-02-29 2014-01-15 ノースウエスタン ユニバーシティ 生物反応促進用バリア
US8685749B2 (en) * 2009-12-02 2014-04-01 Whatman International Limited Methods and systems for processing samples on porous substrates
EP2404672A1 (en) * 2010-07-06 2012-01-11 Universiteit Twente High troughput multiwell system for culturing 3D tissue constructs in-vitro or in-vivo, method for producing said multiwell system and methods for preparing 3D tissue constructs from cells using said multiwell system
CN103140292B (zh) * 2010-07-29 2015-01-21 丹耐克斯技术有限公司 样品板
KR20130100149A (ko) * 2010-09-10 2013-09-09 솔리더스 바이오사이언스, 인코포레이티드 마이크로어레이 세포 칩
US9012205B2 (en) 2011-04-18 2015-04-21 Empire Technology Development Llc Revolving cell culture cartridge and methods of use
GB2493179B (en) * 2011-07-26 2018-09-05 Kratos Analytical Ltd MALDI sample preparation methods and targets
WO2013025543A1 (en) * 2011-08-12 2013-02-21 Solidus Biosciences, Inc. Cell chips
WO2013093954A1 (ja) * 2011-12-19 2013-06-27 ヤマハ発動機株式会社 対象物選別装置および対象物選別方法
JP5827696B2 (ja) * 2011-12-20 2015-12-02 ヤマハ発動機株式会社 対象物選別装置および対象物選別方法
US9423234B2 (en) 2012-11-05 2016-08-23 The Regents Of The University Of California Mechanical phenotyping of single cells: high throughput quantitative detection and sorting
WO2014091524A1 (ja) * 2012-12-13 2014-06-19 ヤマハ発動機株式会社 対象物回収装置
JP2014142220A (ja) * 2013-01-23 2014-08-07 Tokyo Denki Univ pH測定システム、pH測定用装置、pH感応シート及びpH感応シートの製造方法
US20160312164A1 (en) 2013-12-12 2016-10-27 Yamaha Hatsudoki Kabushiki Kaisha Well plate and subject selection device provided with well plate
US10370630B2 (en) 2014-02-10 2019-08-06 Technion Research & Development Foundation Limited Method and apparatus for cell isolation, growth, replication, manipulation, and analysis
US9284596B2 (en) 2014-02-13 2016-03-15 Battelle Energy Alliance, Llc Methods for determining enzymatic activity comprising heating and agitation of closed volumes
CN110042060A (zh) 2014-08-05 2019-07-23 雅马哈发动机株式会社
US10073091B2 (en) 2014-08-08 2018-09-11 Ortho-Clinical Diagnostics, Inc. Lateral flow assay device
GB201501907D0 (en) 2015-02-05 2015-03-25 Technion Res & Dev Foundation System and method for single cell genetic analysis
KR101753961B1 (ko) 2015-06-26 2017-07-04 고려대학교 산학협력단 부유 구조체 및 이를 구비한 반응 물질 전환 시스템
JP6093492B1 (ja) * 2015-09-03 2017-03-08 浜松ホトニクス株式会社 試料支持体、及び試料支持体の製造方法
EP3654365B1 (en) * 2015-09-03 2023-09-13 Hamamatsu Photonics K.K. Mass spectrometry device
JP6934234B2 (ja) 2015-11-25 2021-09-15 一般財団法人生産技術研究奨励会 マイクロチャンバーアレイ装置およびそれを用いた検査対象物の解析方法
CN105603361B (zh) * 2016-01-14 2018-02-27 深圳市国创新能源研究院 高通量生物薄膜的制备方法和应用
DK3472351T3 (da) 2016-06-15 2020-11-09 Univ Muenchen Ludwig Maximilians Enkeltmolekylepåvisning eller -kvantificering ved hjælp af DNA-nanoteknologi
US10084098B2 (en) * 2016-09-30 2018-09-25 Sunpower Corporation Metallization of conductive wires for solar cells
WO2018111765A1 (en) 2016-12-12 2018-06-21 xCella Biosciences, Inc. Methods and systems for screening using microcapillary arrays
KR101943729B1 (ko) * 2016-12-27 2019-01-30 세메스 주식회사 비아홀 충진 방법 및 장치
EP3563149B1 (en) 2016-12-29 2020-10-21 Purehoney Technologies, Inc. Single-use, disposable high-pressure liquid chromatography columns for high-throughput analysis
JP7208902B2 (ja) * 2016-12-30 2023-01-19 エクセラ・バイオサイエンシーズ・インコーポレイテッド マルチステージサンプル回収システム
US11168883B2 (en) 2017-09-29 2021-11-09 Rosemount Aerospace Inc. Flame arrestor with fluid drainage capabilities
JP2019078668A (ja) * 2017-10-25 2019-05-23 株式会社トヨタプロダクションエンジニアリング 応力発光測定システム、応力発光測定方法及び応力発光測定プログラム
US11442039B2 (en) 2018-02-09 2022-09-13 Hamamatsu Photonics K.K. Sample support body, production method for sample support body, and sample ionization method
EP3751274A4 (en) * 2018-02-09 2021-11-03 Hamamatsu Photonics K.K. SAMPLE HOLDER BODY, AND METHOD FOR MANUFACTURING THE SAME
JP7051632B2 (ja) 2018-07-30 2022-04-11 浜松ホトニクス株式会社 試料支持体、試料のイオン化方法、及び質量分析方法
JP7271903B2 (ja) * 2018-10-20 2023-05-12 東洋製罐グループホールディングス株式会社 スフェア培養部材、培養容器、穴開き部材の加工方法、及び洗浄容器
CN113474645A (zh) * 2019-06-20 2021-10-01 松下知识产权经营株式会社 检测方法和检测装置
CN112354570B (zh) * 2019-07-11 2022-02-11 北京理工大学 一种多维微流控电泳芯片及检测装置,检测方法
DE102019219913A1 (de) 2019-12-17 2021-06-17 Lpkf Laser & Electronics Ag Träger für Flüssigkeitstropfen
JP6895552B1 (ja) * 2020-03-06 2021-06-30 浜松ホトニクス株式会社 試料支持体、イオン化方法及び質量分析方法
JP6895553B1 (ja) * 2020-03-06 2021-06-30 浜松ホトニクス株式会社 試料支持体、イオン化方法及び質量分析方法
KR20220143901A (ko) 2020-03-23 2022-10-25 에프. 호프만-라 로슈 아게 세포 기반 분석을 위한 방법 및 장치
JP7365024B2 (ja) * 2020-05-01 2023-10-19 浜松ホトニクス株式会社 試料支持体、イオン化方法及び質量分析方法
GB202103879D0 (en) * 2021-03-19 2021-05-05 Global Life Sciences Solutions Operations UK Ltd Membrane transfer cassette
WO2023194510A1 (en) * 2022-04-05 2023-10-12 Vysens B.V. Method and device for depositing a compound in a gradient on a sensor surface

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4493815A (en) * 1983-07-28 1985-01-15 Bio-Rad Laboratories, Inc. Supporting and filtering biochemical test plate assembly
GB8721018D0 (en) * 1987-09-07 1987-10-14 Alcan Int Ltd Porous inorganic membrane support
US5243037A (en) * 1990-09-21 1993-09-07 E. I. Du Pont De Nemours And Company Poly(fluoroalkyl) sugar reagents for surface modification of supports
US5284753A (en) * 1991-03-20 1994-02-08 Neuro Probe, Inc. Multiple-site chemotactic test apparatus and method
BR9710054A (pt) * 1996-06-28 2000-01-11 Caliper Techn Corp Aparelhos para separar compostos de teste para um efeito sobre um sistema bioquìmico e para detectar ummefeito de um composto de teste sobre um sistema bioquìmico, processos de determinação de se uma amostra contém um composto capaz de afetar um sistema bioquìmico, de separação de uma pluralidade de compostos de teste para um efeito sobre um sistema bioquìmico e usos de um sistema microfluido e de um substrato de ensaio.
EP1009757A1 (en) * 1997-09-04 2000-06-21 Gryphon Sciences Modular protein libraries and methods of preparation
US6576478B1 (en) * 1998-07-14 2003-06-10 Zyomyx, Inc. Microdevices for high-throughput screening of biomolecules
US6406869B1 (en) * 1999-10-22 2002-06-18 Pharmacopeia, Inc. Fluorescent capture assay for kinase activity employing anti-phosphotyrosine antibodies as capture and detection agents
EP1266218A2 (en) * 2000-03-15 2002-12-18 Aviva Biosciences Corporation Apparatus and method for high throughput electrorotation analysis
US7172859B2 (en) * 2000-07-14 2007-02-06 Transform Pharmaceuticals, Inc. System and method for optimizing tissue barrier transfer of compounds
EP1330306A2 (en) * 2000-10-10 2003-07-30 BioTrove, Inc. Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof
WO2003065037A2 (en) * 2002-01-31 2003-08-07 Pion, Inc. Method and apparatus for measuring membrane permeability
US20040241636A1 (en) * 2003-05-30 2004-12-02 Michnick Stephen William Watson Monitoring gene silencing and annotating gene function in living cells

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117630318A (zh) * 2024-01-23 2024-03-01 四川省科源工程技术测试中心有限责任公司 电泳法测定水环境有机物含量的设备及方法
CN117630318B (zh) * 2024-01-23 2024-04-09 四川省科源工程技术测试中心有限责任公司 电泳法测定水环境有机物含量的设备及方法

Also Published As

Publication number Publication date
AU2006279763A1 (en) 2007-02-22
WO2007022026A3 (en) 2008-01-24
EP1920045A2 (en) 2008-05-14
JP2009504161A (ja) 2009-02-05
WO2007022026A2 (en) 2007-02-22
EP1920045A4 (en) 2011-07-06

Similar Documents

Publication Publication Date Title
US9968903B2 (en) Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof
US6716629B2 (en) Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof
CA2619250A1 (en) Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof
JP2009504161A6 (ja) アッセイ、合成及び保管のための装置、並びにその製造法、使用法及び操作法
AU698306B2 (en) Chemical, biochemical and biological processing in thin films
EP1166116B1 (en) Miniaturized cell array methods and apparatus for cell-based screening
US20020001546A1 (en) Methods for screening substances in a microwell array
US20020164824A1 (en) Method and apparatus based on bundled capillaries for high throughput screening
EP2494353B1 (en) An apparatus comprising a plurality of encoded microvessels and a plurality of compartments and a method of reading a plurality of encoded micro vessels
EP0706646A1 (de) Probenträger und seine verwendung
JP2002525600A (ja) 細胞ベースのスクリーニングのための小型化細胞アレイ方法および装置
US20030203366A1 (en) Microarray channel devices produced by a block mold process
WO2002078834A2 (en) Bundled capillaries apparatus for high throughput screening
US20010055801A1 (en) Liquid arrays
WO2002010761A1 (en) Microarrays and their manufacture by slicing
EP1298433A1 (en) Device and method for the generation of arrays of substance mixtures by diffusion

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20130813