CA2612900C - Improved tuberculosis vaccines - Google Patents
Improved tuberculosis vaccines Download PDFInfo
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- CA2612900C CA2612900C CA2612900A CA2612900A CA2612900C CA 2612900 C CA2612900 C CA 2612900C CA 2612900 A CA2612900 A CA 2612900A CA 2612900 A CA2612900 A CA 2612900A CA 2612900 C CA2612900 C CA 2612900C
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- vaccine
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
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- A—HUMAN NECESSITIES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
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- A—HUMAN NECESSITIES
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Oncology (AREA)
- Microbiology (AREA)
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- Biomedical Technology (AREA)
- Zoology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2836319A CA2836319A1 (en) | 2005-06-23 | 2006-06-20 | Tuberculosis vaccines comprising antigens expressed during the latent infection phase |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200500924 | 2005-06-23 | ||
| DKPA200500924 | 2005-06-23 | ||
| DKPA200501393 | 2005-10-05 | ||
| DKPA200501393 | 2005-10-05 | ||
| PCT/DK2006/000356 WO2006136162A2 (en) | 2005-06-23 | 2006-06-20 | Tuberculosis vaccines comprising antigens expressed during the latent infection phase |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2836319A Division CA2836319A1 (en) | 2005-06-23 | 2006-06-20 | Tuberculosis vaccines comprising antigens expressed during the latent infection phase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2612900A1 CA2612900A1 (en) | 2006-12-28 |
| CA2612900C true CA2612900C (en) | 2016-08-09 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2612900A Expired - Fee Related CA2612900C (en) | 2005-06-23 | 2006-06-20 | Improved tuberculosis vaccines |
| CA2836319A Abandoned CA2836319A1 (en) | 2005-06-23 | 2006-06-20 | Tuberculosis vaccines comprising antigens expressed during the latent infection phase |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2836319A Abandoned CA2836319A1 (en) | 2005-06-23 | 2006-06-20 | Tuberculosis vaccines comprising antigens expressed during the latent infection phase |
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| Country | Link |
|---|---|
| US (4) | US7968105B2 (enExample) |
| EP (4) | EP2380589A3 (enExample) |
| JP (2) | JP5219808B2 (enExample) |
| KR (2) | KR101035053B1 (enExample) |
| CN (1) | CN102836425B (enExample) |
| AU (1) | AU2006261445B2 (enExample) |
| BR (1) | BRPI0612833A2 (enExample) |
| CA (2) | CA2612900C (enExample) |
| ES (1) | ES2647070T3 (enExample) |
| IL (3) | IL188222A (enExample) |
| MX (1) | MX2007016165A (enExample) |
| WO (1) | WO2006136162A2 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19529931C1 (de) | 1995-08-02 | 1997-04-03 | Mannesmann Ag | Plattenkokille zur Erzeugung von Strängen aus Stahl |
| EP1523331B1 (en) * | 2002-07-13 | 2013-02-27 | Statens Serum Institut | Therapeutic tb vaccine |
| MX2009010800A (es) * | 2007-04-04 | 2010-01-29 | Infectious Disease Res Inst Id | Composiciones inmunogenicas que comprenden polipeptidos de mycobacterium tuberculosis y fusiones de los mismos. |
| HRP20150177T1 (hr) * | 2007-04-12 | 2015-04-10 | Mico Bio, Inc. | Cjepivo protiv tuberkuloze i postupak upotrebe tog cjepiva |
| WO2009003474A1 (en) * | 2007-06-29 | 2009-01-08 | Statens Serum Institut | The use of monomycolyl glycerol (mmg) as an adjuvant |
| CN101969976A (zh) * | 2008-01-11 | 2011-02-09 | 美国政府健康与人类服务部秘书处 | 针对分枝杆菌的多肽疫苗和接种策略 |
| US20100015171A1 (en) * | 2008-07-15 | 2010-01-21 | Statens Serum Institute | Vaccines comprising tb 10.4 |
| UA107330C2 (uk) | 2008-07-25 | 2014-12-25 | Глаксосмітклайн Байолоджікалз С.А. | Туберкульозний білок rv3616c та його застосування |
| US9603919B2 (en) * | 2009-03-31 | 2017-03-28 | Japan As Represented By The Director-General Of National Institute Of Infectious Diseases | Method for prophylaxis of influenza using vaccine for intranasal administration |
| CN102413837B (zh) | 2009-04-24 | 2015-11-25 | 国立血清研究所 | 预防再激活的结核病tb疫苗 |
| WO2011013097A2 (en) * | 2009-07-29 | 2011-02-03 | Bernd Helmut Adam Rehm | Polymer particles and uses thereof |
| US10357555B2 (en) * | 2012-07-10 | 2019-07-23 | Transgene Sa | Mycobacterial antigen vaccine |
| RU2520078C1 (ru) * | 2013-04-25 | 2014-06-20 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации (ФГБУ "НИИЭМ им. Н.Ф. Гамалеи" Минздрава России) | СПОСОБ ПОЛУЧЕНИЯ ИММУНОГЕННОЙ КОМПОЗИЦИИ НА ОСНОВЕ ГИБРИДНОГО БЕЛКА Ag85A-DBD И ДЕКСТРАНА, РЕКОМБИНАНТНАЯ ПЛАЗМИДА pAg85A-DBD, ШТАММ Escherichia coli [pREP4, pAg85A-DBD], ХИМЕРНЫЙ БЕЛОК Ag85A-DBD |
| RU2520737C1 (ru) * | 2013-04-25 | 2014-06-27 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт эпидемиологии и микробиологии имени почётного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации (ФГБУ "НИИЭМ им. Н.Ф. Гамалеи" Минздрава России) | СПОСОБ ПОЛУЧЕНИЯ ИММУНОГЕННОЙ КОМПОЗИЦИИ НА ОСНОВЕ ГИБРИДНОГО БЕЛКА pESAT6-DBD И ДЕКСТРАНА, РЕКОМБИНАНТНАЯ ПЛАЗМИДА pESAT6-DBD, ШТАММ Escherichia coli, ХИМЕРНЫЙ БЕЛОК ESAT6-DBD И ИХ ПРИМЕНЕНИЕ |
| RU2539026C1 (ru) * | 2013-06-11 | 2015-01-10 | Федеральное государственное бюджетное учреждение "Центральный научно-исследовательский институт туберкулеза" Российской академии медицинских наук | РЕКОМБИНАНТНАЯ ПЛАЗМИДА pESAT6-CFP10-DBD, РЕКОМБИНАНТНЫЙ ШТАММ Escherichia coli M15 [pREP4, pESAT6-CFP10-DBD], СПОСОБ ПОЛУЧЕНИЯ, ИММОБИЛИЗАЦИИ, КОНЦЕНТРИРОВАНИЯ И ОЧИСТКИ РЕКОМБИНАНТНОГО БЕЛКА ESAT6-CFP10-DBD НА ДЕКСТРАНЕ, РЕКОМБИНАНТНЫЙ БЕЛОК ESAT6-CFP10-DBD И ИММУНОГЕННАЯ КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ БЕЛОК ESAT6-CFP10-DBD |
| EP3013364B1 (en) | 2013-06-25 | 2022-08-03 | International AIDS Vaccine Initiative, Inc. | Tuberculosis compositions and methods of using the same |
| RU2695462C2 (ru) * | 2014-01-09 | 2019-07-23 | Трансген Са | Гибридизация гетероолигомерных микобактериальных антигенов |
| WO2017218867A1 (en) * | 2016-06-16 | 2017-12-21 | Aeras | Tuberculosis compositions and methods of treating or preventing tuberculosis |
| CN107970444B (zh) * | 2016-10-25 | 2022-03-01 | 中国人民解放军第三0九医院 | 复合佐剂及含有该复合佐剂的疫苗 |
| PH12021553146A1 (en) * | 2019-06-14 | 2024-04-22 | Statens Seruminstitut | Fusion proteins for tuberculosis vaccines |
| US20250345408A1 (en) * | 2020-09-23 | 2025-11-13 | The General Hospital Corporation | Bcg vaccinations for prevention of covid-19 and other infectious diseases |
| KR102709729B1 (ko) * | 2020-12-04 | 2024-09-25 | 주식회사 제넥신 | 결핵의 예방 또는 치료용 약학적 조성물 |
| CN115598041B (zh) * | 2021-07-07 | 2025-08-19 | 中国科学院微生物研究所 | 结核鉴别诊断细胞因子及其在结核感染风险评估中的应用 |
| KR20240153581A (ko) | 2022-02-21 | 2024-10-23 | 스태튼스 세룸 인스티튜트 | 신규한 양이온 어주번트 조성물 |
| CN117531001A (zh) * | 2023-11-15 | 2024-02-09 | 首都医科大学附属北京胸科医院 | 结核分枝杆菌毒素抗毒素系统及其相关应用 |
| CN118108815B (zh) * | 2024-04-23 | 2024-07-23 | 成都康华生物制品股份有限公司 | 结核分枝杆菌多免疫原抗原、编码其的mRNA、应用 |
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| US4601903A (en) | 1985-05-01 | 1986-07-22 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccine against Neisseria meningitidis Group B serotype 2 invasive disease |
| US6641814B1 (en) | 1997-04-02 | 2003-11-04 | Statens Serum Institut | Nucleic acids fragments and polypeptide fragments derived from M. tuberculosis |
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| ATE339436T1 (de) | 1995-06-07 | 2006-10-15 | Sanofi Pasteur Inc | Expression von lipoproteinen |
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| CN1377355A (zh) | 1999-09-30 | 2002-10-30 | 纽罗杰有限公司 | 氨基取代的吡唑并[1,5－a]－1,5－嘧啶和吡唑并[1,5－a]－1,3,5－三嗪 |
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| WO2002004018A2 (en) | 2000-07-10 | 2002-01-17 | Colorado State University Research Foundation | Mid-life vaccine and methods for boosting anti-mycobacterial immunity |
| US20030180953A1 (en) * | 2000-12-29 | 2003-09-25 | Elitra Pharmaceuticals, Inc. | Gene disruption methodologies for drug target discovery |
| US20030119013A1 (en) * | 2001-04-23 | 2003-06-26 | Bo Jiang | Identification of essential genes of Aspergillus fumigatus and methods of use |
| EP2196473A1 (en) * | 2001-07-04 | 2010-06-16 | Health Protection Agency | Mycobacterial antigens expressed during latency |
| EP1523331B1 (en) * | 2002-07-13 | 2013-02-27 | Statens Serum Institut | Therapeutic tb vaccine |
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