CA2612394C - Her-2 peptides - Google Patents

Her-2 peptides Download PDF

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Publication number
CA2612394C
CA2612394C CA2612394A CA2612394A CA2612394C CA 2612394 C CA2612394 C CA 2612394C CA 2612394 A CA2612394 A CA 2612394A CA 2612394 A CA2612394 A CA 2612394A CA 2612394 C CA2612394 C CA 2612394C
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CA
Canada
Prior art keywords
seq
epitope
sequence
epitopes
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2612394A
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English (en)
French (fr)
Other versions
CA2612394A1 (en
Inventor
Pravin T. P. Kaumaya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ohio State University Research Foundation
Original Assignee
Ohio State University Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ohio State University Research Foundation filed Critical Ohio State University Research Foundation
Publication of CA2612394A1 publication Critical patent/CA2612394A1/en
Application granted granted Critical
Publication of CA2612394C publication Critical patent/CA2612394C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82Translation products from oncogenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Mycology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2612394A 2005-06-15 2006-06-15 Her-2 peptides Active CA2612394C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69057405P 2005-06-15 2005-06-15
US60/690,574 2005-06-15
PCT/US2006/023672 WO2006138675A2 (en) 2005-06-15 2006-06-15 Her-2 peptides

Publications (2)

Publication Number Publication Date
CA2612394A1 CA2612394A1 (en) 2006-12-28
CA2612394C true CA2612394C (en) 2017-02-21

Family

ID=37571268

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2612394A Active CA2612394C (en) 2005-06-15 2006-06-15 Her-2 peptides

Country Status (7)

Country Link
US (3) US7691396B2 (es)
EP (1) EP1912680B1 (es)
JP (2) JP5222134B2 (es)
AU (1) AU2006261342B2 (es)
CA (1) CA2612394C (es)
ES (1) ES2531483T3 (es)
WO (1) WO2006138675A2 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1246597B1 (en) * 1999-08-03 2015-01-14 The Ohio State University Polypeptides and polynucleotides for enhancing immune reactivity to her-2 protein
EP1912680B1 (en) 2005-06-15 2014-11-26 The Ohio State University Research Foundation Her-2 peptides
US8945573B2 (en) * 2005-09-08 2015-02-03 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Targeted identification of immunogenic peptides
WO2008097229A1 (en) * 2007-02-09 2008-08-14 The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health And Human Services Method for spectroscopic quantitation of her-2 in biological samples
KR20110008227A (ko) * 2008-04-22 2011-01-26 케메탈 푸테 코포레이션 고순도 수산화리튬 및 염화수소산의 제조 방법
US20100234283A1 (en) 2009-02-04 2010-09-16 The Ohio State University Research Foundation Immunogenic epitopes, peptidomimetics, and anti-peptide antibodies, and methods of their use
US9125848B2 (en) 2010-06-10 2015-09-08 The Cleveland Clinic Foundation Alpha lactalbumin immunization methods
EP2621945B1 (en) * 2010-09-28 2018-04-11 NoNO Inc. Nd2 peptides and methods of treating neurological disease
RU2645085C2 (ru) 2012-04-16 2018-02-15 Дзе Кливленд Клиник Фаундейшн Мультивалентная вакцина против рака молочной железы
WO2014131019A2 (en) 2013-02-25 2014-08-28 Ohio State Innovation Foundation Her-1, her-3 and igf-1r compositions and uses thereof
CN105017425B (zh) * 2014-04-30 2018-02-16 京天成生物技术(北京)有限公司 抗her2中和活性单克隆抗体及其应用
WO2017078761A2 (en) * 2015-11-06 2017-05-11 Evorx Technologies, Inc. Her-2-specific cyclized supr peptides
EP3576764A4 (en) 2017-02-03 2020-12-16 The Medical College of Wisconsin, Inc. KRAS PEPTIDE VACCINE COMPOSITIONS AND METHOD OF USE
BR112019020386A2 (pt) 2017-03-28 2020-06-09 Mayo Found Medical Education & Res vacinas de peptídeos de pd-1 humana e usos das mesmas
US20200179500A1 (en) * 2018-12-05 2020-06-11 Wayne State University Methods and immunogenic compositions relating to her2 with selective sequence modifications
JP2022529232A (ja) * 2019-03-22 2022-06-20 オリビア・ニュートン-ジョン・キャンサー・リサーチ・インスティテュート 抗her2結合分子
WO2023161526A1 (en) 2022-02-28 2023-08-31 Tridem Bioscience Gmbh & Co Kg A CONJUGATE CONSISTING OF OR COMPRISING AT LEAST A ß-GLUCAN OR A MANNAN

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3040121B2 (ja) * 1988-01-12 2000-05-08 ジェネンテク,インコーポレイテッド 増殖因子レセプターの機能を阻害することにより腫瘍細胞を処置する方法
DE69031120T2 (de) * 1989-05-19 1998-01-15 Genentech Inc Her2 extrazellulare domäne
ES2070492T3 (es) * 1990-01-26 1995-06-01 Washington Res Found Reactividad inmunitaria para oncogenes expresados activos para diagnostico y tratamiento de estados malignos.
IL101943A0 (en) * 1991-05-24 1992-12-30 Genentech Inc Structure,production and use of heregulin
DK0761231T3 (da) 1992-06-25 2000-05-08 Smithkline Beecham Biolog Vaccinepræparat indeholdende adjuvanser
EP0839050B1 (en) 1992-09-28 2004-08-11 Wyeth Holdings Corporation Method of enhancing cell mediated immune responses
EP0662839A4 (en) 1992-09-30 1995-09-06 Univ Ohio State Res Found ANTIGENIC VACCINES AND CONJUGATES.
US5869445A (en) * 1993-03-17 1999-02-09 University Of Washington Methods for eliciting or enhancing reactivity to HER-2/neu protein
US5801005A (en) * 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
GB9326253D0 (en) 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
ATE420171T1 (de) 1994-07-15 2009-01-15 Univ Iowa Res Found Immunomodulatorische oligonukleotide
UA56132C2 (uk) 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
US6410022B1 (en) 1995-05-01 2002-06-25 Avant Immunotherapeutics, Inc. Modulation of cholesteryl ester transfer protein (CETP) activity
CA2251464A1 (en) * 1996-04-03 1997-10-16 Pepresearch A/S Non-dendritic backbone peptide carrier
EP1106183A3 (en) 1996-10-18 2001-09-12 Genentech, Inc. Antibodies to erbB2 and their therapeutic uses
CN1181422A (zh) * 1996-10-31 1998-05-13 上海市肿瘤研究所 与生长因子受体结合的多肽所构建的基因转移载体
DE69827138T2 (de) 1997-08-11 2006-02-23 Allergan, Inc., Irvine Steriles Retinoid enthaltendes biodegradierbares Implantat mit verbesserter Biokompatibilität und Verfahren zu dessen Herstellung
ZA9811162B (en) 1997-12-12 2000-06-07 Genentech Inc Treatment with anti-ERBB2 antibodies.
EP0953823A2 (en) 1998-05-01 1999-11-03 Aisin Cosmos R & D Co. Ltd. Micro yaw rate sensors
WO2000034337A1 (en) 1998-12-10 2000-06-15 Tsukuba Research Laboratory, Toagosei Co., Ltd. Humanized monoclonal antibodies against vascular endothelial cell growth factor
EP1187632B1 (en) * 1999-05-14 2008-12-03 Genentech, Inc. TREATMENT WITH ANTI-ErbB2 ANTIBODIES
EP1246597B1 (en) * 1999-08-03 2015-01-14 The Ohio State University Polypeptides and polynucleotides for enhancing immune reactivity to her-2 protein
US6432409B1 (en) 1999-09-14 2002-08-13 Antigen Express, Inc. Hybrid peptides modulate the immune response
US20030235594A1 (en) * 1999-09-14 2003-12-25 Antigen Express, Inc. Ii-Key/antigenic epitope hybrid peptide vaccines
AU2001295008A1 (en) * 2000-08-14 2002-02-25 Corixa Corporation Compositions and methods for the therapy and diagnosis of Her-2/neu-associated malignancies
GB0213878D0 (en) * 2002-06-17 2002-07-31 Protherics Plc Use
JP2006515744A (ja) * 2002-09-17 2006-06-08 アンテイジエン・エクスプレス・インコーポレーテツド Ii−Key/抗原性エピトープハイブリッドペプチドワクチン
ATE441715T1 (de) * 2003-03-04 2009-09-15 Intercell Ag Streptococcus pyogenes antigene
NZ544828A (en) * 2003-06-25 2008-10-31 Ottawa Health Research Inst Use of cardiotrophin to modulate stem cell proliferation
DE602004028266D1 (de) * 2003-10-29 2010-09-02 Univ Ramot Angiogene peptide und ihre verwendungen
CA2555274A1 (en) * 2004-02-05 2005-08-25 The Ohio State University Research Foundation Chimeric vegf peptides
SE0402565L (sv) 2004-10-19 2005-12-20 Mia Kumm Anordning och system för ventilation av tunnel vid brand
EP1829968A4 (en) * 2004-12-20 2008-09-10 Ajinomoto Kk PROTEIN MUTANT WITH PEPTIDE PRODUCTION ACTIVITY
EP1912680B1 (en) 2005-06-15 2014-11-26 The Ohio State University Research Foundation Her-2 peptides
US20100234283A1 (en) * 2009-02-04 2010-09-16 The Ohio State University Research Foundation Immunogenic epitopes, peptidomimetics, and anti-peptide antibodies, and methods of their use
JP5510272B2 (ja) 2010-06-21 2014-06-04 株式会社リコー 画像形成装置

Also Published As

Publication number Publication date
AU2006261342B2 (en) 2012-02-02
JP2009500298A (ja) 2009-01-08
EP1912680A2 (en) 2008-04-23
EP1912680B1 (en) 2014-11-26
US7691396B2 (en) 2010-04-06
AU2006261342A1 (en) 2006-12-28
US9452204B2 (en) 2016-09-27
JP5542865B2 (ja) 2014-07-09
WO2006138675A9 (en) 2010-01-28
ES2531483T3 (es) 2015-03-16
JP5222134B2 (ja) 2013-06-26
EP1912680A4 (en) 2010-09-22
US20110086055A1 (en) 2011-04-14
WO2006138675A2 (en) 2006-12-28
US20140010831A1 (en) 2014-01-09
CA2612394A1 (en) 2006-12-28
US20070060516A1 (en) 2007-03-15
JP2012136555A (ja) 2012-07-19
US8470333B2 (en) 2013-06-25

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