CA2609985A1 - Modulation of cell barrier dysfunction - Google Patents
Modulation of cell barrier dysfunction Download PDFInfo
- Publication number
- CA2609985A1 CA2609985A1 CA002609985A CA2609985A CA2609985A1 CA 2609985 A1 CA2609985 A1 CA 2609985A1 CA 002609985 A CA002609985 A CA 002609985A CA 2609985 A CA2609985 A CA 2609985A CA 2609985 A1 CA2609985 A1 CA 2609985A1
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- opioid receptor
- opioid
- aeruginosa
- receptor antagonist
- cell
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68756805P | 2005-06-03 | 2005-06-03 | |
US60/687,568 | 2005-06-03 | ||
US73100905P | 2005-10-28 | 2005-10-28 | |
US60/731,009 | 2005-10-28 | ||
US76085106P | 2006-01-20 | 2006-01-20 | |
US60/760,851 | 2006-01-20 | ||
PCT/US2006/007892 WO2006096626A2 (en) | 2005-03-07 | 2006-03-07 | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
USPCT/US2006/07892 | 2006-03-07 | ||
PCT/US2006/021604 WO2007053194A2 (en) | 2005-06-03 | 2006-06-05 | Modulation of cell barrier dysfunction |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2609985A1 true CA2609985A1 (en) | 2007-05-10 |
Family
ID=38006351
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002609985A Abandoned CA2609985A1 (en) | 2005-06-03 | 2006-06-05 | Modulation of cell barrier dysfunction |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1901742A2 (de) |
CA (1) | CA2609985A1 (de) |
WO (1) | WO2007053194A2 (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI2368553T1 (sl) | 2003-04-08 | 2015-05-29 | Progenics Pharmaceuticals, Inc. | Farmacevtske formulacije, vsebujoče metilnatrekson |
US8518962B2 (en) | 2005-03-07 | 2013-08-27 | The University Of Chicago | Use of opioid antagonists |
US9662325B2 (en) | 2005-03-07 | 2017-05-30 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
ES2714198T3 (es) | 2005-03-07 | 2019-05-27 | Univ Chicago | Uso de antagonistas opioideos para atenuar la proliferación y la migración de células endoteliales |
US8524731B2 (en) * | 2005-03-07 | 2013-09-03 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
JP2009534384A (ja) * | 2006-04-19 | 2009-09-24 | ジル・ピー・スミス | オピオイドアンタゴニストによる炎症性および潰瘍性腸疾患の治療 |
EP3064503A1 (de) | 2007-03-29 | 2016-09-07 | Progenics Pharmaceuticals, Inc. | Antagonisten der peripheren opioidrezeptoren und ihre verwendung |
PT2139890E (pt) | 2007-03-29 | 2014-09-03 | Wyeth Llc | Antagonistas do receptor opióide periférico e respectivas utilizações |
MX2009010550A (es) | 2007-03-29 | 2009-12-14 | Progenics Pharm Inc | Formas de cristal de bromuro de (r)-n-metilnaltrexona y uso de las mismas. |
BRPI0817804A8 (pt) * | 2007-10-05 | 2017-04-18 | Toray Industries | Agente terapêutico para melhorar as propriedades da pele compreendendo um derivado de morfinano ou qualquer um de seus sais de adição de ácido farmacologicamente permissíveis como um ingrediente ativo |
CA2713568C (en) | 2008-02-06 | 2016-09-20 | Progenics Pharmaceuticals, Inc. | Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone |
WO2009117669A2 (en) | 2008-03-21 | 2009-09-24 | The University Of Chicago | Treatment with opioid antagonists and mtor inhibitors |
ES2620373T3 (es) | 2008-07-01 | 2017-06-28 | University Of Chicago | Partículas que contienen un antagonista del receptor de opioides periférico |
CA2676881C (en) | 2008-09-30 | 2017-04-25 | Wyeth | Peripheral opioid receptor antagonists and uses thereof |
ES2951828T3 (es) | 2010-09-23 | 2023-10-25 | Leading Biosciences Inc | Administración de inhibidores de serina proteasa al estómago |
US10485798B2 (en) | 2012-08-22 | 2019-11-26 | Aptapharma Inc. | Methylnaltrexone nasal formulations, methods of making, and use thereof |
MX2016012248A (es) | 2014-03-25 | 2017-04-27 | Leading Biosciences Inc | Composiciones para el tratamiento de autodigestion. |
CN117940554A (zh) * | 2022-06-30 | 2024-04-26 | 上海羽冠生物技术有限公司 | 假单胞菌属的活细菌菌株 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4863928A (en) * | 1989-01-04 | 1989-09-05 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for arthritic and inflammatory diseases |
US20040024006A1 (en) * | 1996-05-06 | 2004-02-05 | Simon David Lew | Opioid pharmaceutical compositions |
US6194382B1 (en) * | 1999-03-03 | 2001-02-27 | Albert Einstein College Of Medicine Of Yeshiva University | Method and composition for treating irritable bowel syndrome using low doses of opioid receptor antagonists |
US6384044B1 (en) * | 1999-11-29 | 2002-05-07 | Bernard Bihari | Method of treating cancer of the prostate |
CA2610951A1 (en) * | 2005-06-03 | 2006-12-14 | The University Of Chicago | Modulation of microbial pathogen-host cell interactions |
-
2006
- 2006-06-05 WO PCT/US2006/021604 patent/WO2007053194A2/en active Application Filing
- 2006-06-05 CA CA002609985A patent/CA2609985A1/en not_active Abandoned
- 2006-06-05 EP EP06844131A patent/EP1901742A2/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP1901742A2 (de) | 2008-03-26 |
WO2007053194A2 (en) | 2007-05-10 |
WO2007053194A3 (en) | 2007-08-09 |
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