CA2606643C - System for automatically producing radioisotopes - Google Patents
System for automatically producing radioisotopes Download PDFInfo
- Publication number
- CA2606643C CA2606643C CA2606643A CA2606643A CA2606643C CA 2606643 C CA2606643 C CA 2606643C CA 2606643 A CA2606643 A CA 2606643A CA 2606643 A CA2606643 A CA 2606643A CA 2606643 C CA2606643 C CA 2606643C
- Authority
- CA
- Canada
- Prior art keywords
- unit
- target
- target carrier
- transfer means
- electrodissolution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000004070 electrodeposition Methods 0.000 claims abstract description 15
- 239000012535 impurity Substances 0.000 claims abstract description 8
- 230000001678 irradiating effect Effects 0.000 claims abstract description 4
- 238000000034 method Methods 0.000 claims abstract description 4
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims description 29
- 229910052751 metal Inorganic materials 0.000 claims description 17
- 239000002184 metal Substances 0.000 claims description 17
- 229910052697 platinum Inorganic materials 0.000 claims description 15
- 238000005868 electrolysis reaction Methods 0.000 claims description 13
- 239000011248 coating agent Substances 0.000 claims description 8
- 238000000576 coating method Methods 0.000 claims description 8
- 238000005192 partition Methods 0.000 claims description 6
- 230000002285 radioactive effect Effects 0.000 claims description 5
- 229910052741 iridium Inorganic materials 0.000 claims description 3
- GKOZUEZYRPOHIO-UHFFFAOYSA-N iridium atom Chemical compound [Ir] GKOZUEZYRPOHIO-UHFFFAOYSA-N 0.000 claims description 3
- 229910052758 niobium Inorganic materials 0.000 claims description 3
- 239000010955 niobium Substances 0.000 claims description 3
- GUCVJGMIXFAOAE-UHFFFAOYSA-N niobium atom Chemical compound [Nb] GUCVJGMIXFAOAE-UHFFFAOYSA-N 0.000 claims description 3
- 239000004411 aluminium Substances 0.000 claims description 2
- 229910052782 aluminium Inorganic materials 0.000 claims description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 2
- 239000000969 carrier Substances 0.000 claims description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 2
- 229910052737 gold Inorganic materials 0.000 claims description 2
- 239000010931 gold Substances 0.000 claims description 2
- 229910001220 stainless steel Inorganic materials 0.000 claims description 2
- 239000010935 stainless steel Substances 0.000 claims description 2
- 239000000243 solution Substances 0.000 description 19
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 14
- 239000002253 acid Substances 0.000 description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- 229910052759 nickel Inorganic materials 0.000 description 7
- 238000000746 purification Methods 0.000 description 7
- 239000008151 electrolyte solution Substances 0.000 description 6
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 5
- 238000004090 dissolution Methods 0.000 description 5
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
- 238000004140 cleaning Methods 0.000 description 4
- 239000008367 deionised water Substances 0.000 description 4
- 229910021641 deionized water Inorganic materials 0.000 description 4
- 235000019441 ethanol Nutrition 0.000 description 4
- 229910017604 nitric acid Inorganic materials 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 239000003054 catalyst Substances 0.000 description 2
- 239000000498 cooling water Substances 0.000 description 2
- 238000000151 deposition Methods 0.000 description 2
- 230000008021 deposition Effects 0.000 description 2
- 239000001307 helium Substances 0.000 description 2
- 229910052734 helium Inorganic materials 0.000 description 2
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 2
- APFVFJFRJDLVQX-FTXFMUIASA-N indium-110 Chemical compound [110In] APFVFJFRJDLVQX-FTXFMUIASA-N 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- JBNOVHJXQSHGRL-UHFFFAOYSA-N 7-amino-4-(trifluoromethyl)coumarin Chemical compound FC(F)(F)C1=CC(=O)OC2=CC(N)=CC=C21 JBNOVHJXQSHGRL-UHFFFAOYSA-N 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 1
- 239000004327 boric acid Substances 0.000 description 1
- 239000012876 carrier material Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 238000004255 ion exchange chromatography Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- LGQLOGILCSXPEA-UHFFFAOYSA-L nickel sulfate Chemical compound [Ni+2].[O-]S([O-])(=O)=O LGQLOGILCSXPEA-UHFFFAOYSA-L 0.000 description 1
- 238000002600 positron emission tomography Methods 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000000844 transformation Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25C—PROCESSES FOR THE ELECTROLYTIC PRODUCTION, RECOVERY OR REFINING OF METALS; APPARATUS THEREFOR
- C25C1/00—Electrolytic production, recovery or refining of metals by electrolysis of solutions
- C25C1/22—Electrolytic production, recovery or refining of metals by electrolysis of solutions of metals not provided for in groups C25C1/02 - C25C1/20
-
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25C—PROCESSES FOR THE ELECTROLYTIC PRODUCTION, RECOVERY OR REFINING OF METALS; APPARATUS THEREFOR
- C25C7/00—Constructional parts, or assemblies thereof, of cells; Servicing or operating of cells
- C25C7/007—Constructional parts, or assemblies thereof, of cells; Servicing or operating of cells of cells comprising at least a movable electrode
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G4/00—Radioactive sources
- G21G4/04—Radioactive sources other than neutron sources
- G21G4/06—Radioactive sources other than neutron sources characterised by constructional features
- G21G4/08—Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical application
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H6/00—Targets for producing nuclear reactions
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- High Energy & Nuclear Physics (AREA)
- Electrochemistry (AREA)
- Organic Chemistry (AREA)
- Metallurgy (AREA)
- Materials Engineering (AREA)
- Optics & Photonics (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Plasma & Fusion (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Electrolytic Production Of Metals (AREA)
- Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
- Radiation-Therapy Devices (AREA)
- Medicines Containing Plant Substances (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Particle Accelerators (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05425262A EP1717819B1 (de) | 2005-04-27 | 2005-04-27 | System zur automatischen Gewinnung von Radioisotopen |
| EP05425262.2 | 2005-04-27 | ||
| PCT/EP2006/061853 WO2006114433A2 (en) | 2005-04-27 | 2006-04-26 | System for automatically producing radioisotopes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2606643A1 CA2606643A1 (en) | 2006-11-02 |
| CA2606643C true CA2606643C (en) | 2013-09-03 |
Family
ID=35677483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2606643A Active CA2606643C (en) | 2005-04-27 | 2006-04-26 | System for automatically producing radioisotopes |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20100025251A1 (de) |
| EP (1) | EP1717819B1 (de) |
| AT (1) | ATE517418T1 (de) |
| CA (1) | CA2606643C (de) |
| DK (1) | DK1717819T3 (de) |
| ES (1) | ES2369482T3 (de) |
| WO (1) | WO2006114433A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7781744B2 (en) * | 2008-08-21 | 2010-08-24 | Comecer S.P.A. | Procedure for the preparation of radioisotopes |
| DE102009005893B3 (de) * | 2009-01-23 | 2010-12-02 | Forschungszentrum Jülich GmbH | Verfahren zur Erzeugung von 11C sowie Targetkörper |
| JP5322071B2 (ja) * | 2010-09-22 | 2013-10-23 | 独立行政法人放射線医学総合研究所 | 加速器による放射性核種の製造方法及び装置 |
| US9991013B2 (en) | 2015-06-30 | 2018-06-05 | General Electric Company | Production assemblies and removable target assemblies for isotope production |
| EP3608921B1 (de) | 2018-08-06 | 2020-12-16 | Ion Beam Applications S.A. | Kapsel für ein targetmaterial und einrichtung zur bestrahlung dieses targetmaterials |
| CA3109824A1 (en) * | 2018-08-27 | 2020-03-05 | BWXT Isotope Technology Group, Inc. | Target irradiation systems for the production of radioisotopes |
| JPWO2020196793A1 (de) * | 2019-03-28 | 2020-10-01 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA935943A (en) * | 1970-12-23 | 1973-10-23 | Union Carbide Corporation | Primary target for the production of fission products in a nuclear reactor and process for preparation |
| US5037602A (en) * | 1989-03-14 | 1991-08-06 | Science Applications International Corporation | Radioisotope production facility for use with positron emission tomography |
| US5223434A (en) * | 1990-11-13 | 1993-06-29 | Kazuo Uemura | Apparatus and method for producing and automatically injecting H21 O |
| AU7265096A (en) * | 1995-08-09 | 1997-03-12 | Newton Scientific, Inc. | Production of 64cu and other radionuclides using charged-particle accelerator |
| US6153154A (en) * | 1998-05-27 | 2000-11-28 | Battelle Memorial Institute | Method for sequential injection of liquid samples for radioisotope separations |
| US6157036A (en) * | 1998-12-02 | 2000-12-05 | Cedars-Sinai Medical Center | System and method for automatically eluting and concentrating a radioisotope |
| US6221437B1 (en) * | 1999-04-12 | 2001-04-24 | Reynolds Tech Fabricators, Inc. | Heated workpiece holder for wet plating bath |
| US20050006245A1 (en) * | 2003-07-08 | 2005-01-13 | Applied Materials, Inc. | Multiple-step electrodeposition process for direct copper plating on barrier metals |
| EP1512774A1 (de) * | 2003-09-08 | 2005-03-09 | Ion Beam Applications S.A. | Verfahren und Vorrichtung zur elektrolytischen Auflösung von Elementen |
| WO2006035424A2 (en) * | 2004-09-28 | 2006-04-06 | Soreq Nuclear Research Center Israel Atomic Energy Commission | Method and system for production of radioisotopes, and radioisotopes produced thereby |
-
2005
- 2005-04-27 AT AT05425262T patent/ATE517418T1/de not_active IP Right Cessation
- 2005-04-27 EP EP05425262A patent/EP1717819B1/de active Active
- 2005-04-27 DK DK05425262.2T patent/DK1717819T3/da active
- 2005-04-27 ES ES05425262T patent/ES2369482T3/es active Active
-
2006
- 2006-04-24 US US11/919,509 patent/US20100025251A1/en not_active Abandoned
- 2006-04-26 WO PCT/EP2006/061853 patent/WO2006114433A2/en active Application Filing
- 2006-04-26 CA CA2606643A patent/CA2606643C/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2369482T3 (es) | 2011-12-01 |
| WO2006114433A3 (en) | 2007-02-22 |
| CA2606643A1 (en) | 2006-11-02 |
| EP1717819A1 (de) | 2006-11-02 |
| DK1717819T3 (da) | 2011-11-07 |
| EP1717819B1 (de) | 2011-07-20 |
| ATE517418T1 (de) | 2011-08-15 |
| WO2006114433A2 (en) | 2006-11-02 |
| US20100025251A1 (en) | 2010-02-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |