CA2604907A1 - Combination cancer therapy with bis(thiohydrazide) amide compounds - Google Patents

Combination cancer therapy with bis(thiohydrazide) amide compounds Download PDF

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Publication number
CA2604907A1
CA2604907A1 CA002604907A CA2604907A CA2604907A1 CA 2604907 A1 CA2604907 A1 CA 2604907A1 CA 002604907 A CA002604907 A CA 002604907A CA 2604907 A CA2604907 A CA 2604907A CA 2604907 A1 CA2604907 A1 CA 2604907A1
Authority
CA
Canada
Prior art keywords
methyl
bis
optionally substituted
cancer
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002604907A
Other languages
English (en)
French (fr)
Inventor
Thomas A. Dahl
Matthew Mcleod
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synta Phamaceuticals Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2604907A1 publication Critical patent/CA2604907A1/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002604907A 2005-04-15 2006-04-13 Combination cancer therapy with bis(thiohydrazide) amide compounds Abandoned CA2604907A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67213905P 2005-04-15 2005-04-15
US60/672,139 2005-04-15
PCT/US2006/014531 WO2006113695A1 (en) 2005-04-15 2006-04-13 Combination cancer therapy with bis(thiohydrazide) amide compounds

Publications (1)

Publication Number Publication Date
CA2604907A1 true CA2604907A1 (en) 2006-10-26

Family

ID=36694110

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002604907A Abandoned CA2604907A1 (en) 2005-04-15 2006-04-13 Combination cancer therapy with bis(thiohydrazide) amide compounds

Country Status (11)

Country Link
US (2) US8017654B2 (enExample)
EP (1) EP1877048A1 (enExample)
JP (1) JP2008536875A (enExample)
AU (1) AU2006236378B2 (enExample)
BR (1) BRPI0610219A2 (enExample)
CA (1) CA2604907A1 (enExample)
IL (1) IL186662A (enExample)
MX (1) MX2007012688A (enExample)
NZ (1) NZ562572A (enExample)
WO (1) WO2006113695A1 (enExample)
ZA (1) ZA200708703B (enExample)

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Also Published As

Publication number Publication date
US8017654B2 (en) 2011-09-13
AU2006236378B2 (en) 2010-12-02
BRPI0610219A2 (pt) 2010-06-08
ZA200708703B (en) 2008-11-26
US20090137682A1 (en) 2009-05-28
WO2006113695A1 (en) 2006-10-26
US20120232134A1 (en) 2012-09-13
JP2008536875A (ja) 2008-09-11
EP1877048A1 (en) 2008-01-16
MX2007012688A (es) 2008-03-14
AU2006236378A1 (en) 2006-10-26
IL186662A (en) 2014-01-30
NZ562572A (en) 2011-01-28
IL186662A0 (en) 2008-06-05

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FZDE Discontinued