CA2600712A1 - Methods of treating cancer using ppar-gamma antagonists - Google Patents
Methods of treating cancer using ppar-gamma antagonists Download PDFInfo
- Publication number
- CA2600712A1 CA2600712A1 CA002600712A CA2600712A CA2600712A1 CA 2600712 A1 CA2600712 A1 CA 2600712A1 CA 002600712 A CA002600712 A CA 002600712A CA 2600712 A CA2600712 A CA 2600712A CA 2600712 A1 CA2600712 A1 CA 2600712A1
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- cancer
- antagonist
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- ppar
- agent
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- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
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Landscapes
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- Veterinary Medicine (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66102405P | 2005-03-14 | 2005-03-14 | |
| US60/661,024 | 2005-03-14 | ||
| PCT/US2006/009309 WO2006099479A2 (en) | 2005-03-14 | 2006-03-14 | Methods of treating cancer using ppar-gamma antagonists |
Publications (1)
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| CA2600712A1 true CA2600712A1 (en) | 2006-09-21 |
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| CA002600712A Abandoned CA2600712A1 (en) | 2005-03-14 | 2006-03-14 | Methods of treating cancer using ppar-gamma antagonists |
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| EP (1) | EP1858512A4 (enExample) |
| JP (1) | JP2008533161A (enExample) |
| AU (1) | AU2006223000B2 (enExample) |
| CA (1) | CA2600712A1 (enExample) |
| WO (1) | WO2006099479A2 (enExample) |
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| WO2008094860A2 (en) | 2007-01-30 | 2008-08-07 | Allergan, Inc. | Treating ocular diseases using peroxisome proliferator-activated receptor delta antagonists |
| US20080206194A1 (en) * | 2007-02-16 | 2008-08-28 | Glazer Robert I | Method for the treatment of breast cancer |
| CA2761120A1 (en) * | 2009-05-06 | 2010-11-11 | Biotest Ag | Uses of immunoconjugates targeting cd138 |
| CA3254026A1 (en) * | 2022-03-08 | 2023-09-14 | Flare Therapeutics Inc. | Inverse PPARG agonists and their uses |
| AU2023231613A1 (en) * | 2022-03-08 | 2024-09-05 | Flare Therapeutics Inc. | Pparg inverse agonists and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US7585512B1 (en) * | 1990-05-08 | 2009-09-08 | Thomas Jefferson University | Composition and method of using tumor cells |
| DE69726182T2 (de) * | 1996-12-11 | 2004-08-12 | Dana-Farber Cancer Institute, Inc., Boston | Methoden und pharmazeutische zusammenstellungen zur wachstumsverhinderung von tumorzellen enthaltend einen ppar-gamma agonisten und einen map kinase inhibitor |
| PL357678A1 (en) * | 2000-04-28 | 2004-07-26 | Sankyo Company, Limited | Ppargamma modulators |
| AU2002303156A1 (en) * | 2001-03-23 | 2002-10-08 | Bethesda Pharmaceuticals, Inc. | Design and synthesis of optimized ligands for ppar |
| US6972175B2 (en) * | 2002-11-27 | 2005-12-06 | David Pinsky | Inhibition of Egr-1 expression by ppar-gamma agonists and related compositions and methods |
| KR100576575B1 (ko) * | 2003-09-16 | 2006-05-04 | 한국생명공학연구원 | 피피에이알감마에 대한 단일클론 항체, 특이 항체분비 융합세포주 및 항체를 이용한 염증, 암, 대사성 질환과 같은 질병 관련 조절인자를 검색하는 방법 |
| WO2005077126A2 (en) * | 2004-02-10 | 2005-08-25 | Boston Medical Center Corporation | Use of ppargamma specific inhibitors as anti-cancer therapeutics |
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2006
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- 2006-03-14 AU AU2006223000A patent/AU2006223000B2/en not_active Ceased
- 2006-03-14 JP JP2008501998A patent/JP2008533161A/ja active Pending
- 2006-03-14 WO PCT/US2006/009309 patent/WO2006099479A2/en not_active Ceased
- 2006-03-14 CA CA002600712A patent/CA2600712A1/en not_active Abandoned
- 2006-03-14 EP EP06738374A patent/EP1858512A4/en not_active Withdrawn
Also Published As
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| EP1858512A4 (en) | 2009-08-05 |
| JP2008533161A (ja) | 2008-08-21 |
| US20060217425A1 (en) | 2006-09-28 |
| AU2006223000A1 (en) | 2006-09-21 |
| WO2006099479A2 (en) | 2006-09-21 |
| EP1858512A2 (en) | 2007-11-28 |
| WO2006099479A3 (en) | 2006-11-16 |
| AU2006223000B2 (en) | 2011-06-30 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20131108 |