CA2584562A1 - Yeast-based therapeutic for chronic hepatitis c infection - Google Patents
Yeast-based therapeutic for chronic hepatitis c infection Download PDFInfo
- Publication number
- CA2584562A1 CA2584562A1 CA002584562A CA2584562A CA2584562A1 CA 2584562 A1 CA2584562 A1 CA 2584562A1 CA 002584562 A CA002584562 A CA 002584562A CA 2584562 A CA2584562 A CA 2584562A CA 2584562 A1 CA2584562 A1 CA 2584562A1
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- hcv
- vaccine
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- fusion protein
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- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/35—Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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Applications Claiming Priority (3)
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| US62015804P | 2004-10-18 | 2004-10-18 | |
| US60/620,158 | 2004-10-18 | ||
| PCT/US2005/037499 WO2006044923A2 (en) | 2004-10-18 | 2005-10-18 | Yeast-based therapeutic for chronic hepatitis c infection |
Publications (1)
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| CA2584562A1 true CA2584562A1 (en) | 2006-04-27 |
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| CA002584562A Abandoned CA2584562A1 (en) | 2004-10-18 | 2005-10-18 | Yeast-based therapeutic for chronic hepatitis c infection |
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| EP (2) | EP2460533A3 (https=) |
| JP (3) | JP2008516610A (https=) |
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| CA (1) | CA2584562A1 (https=) |
| IL (1) | IL182609A (https=) |
| MX (1) | MX2007004662A (https=) |
| SG (1) | SG156652A1 (https=) |
| WO (1) | WO2006044923A2 (https=) |
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| KR20080043775A (ko) | 2005-07-11 | 2008-05-19 | 글로브이뮨 | 표적 치료용 회피 돌연변이체에 대한 면역 반응의 유발방법 및 조성물 |
| BRPI0715714A2 (pt) | 2006-08-25 | 2014-03-11 | Wyeth Corp | Métodos para diminuir a frequência de emergência de uma infecção viral de hepatite c resistente ao tratamento, para atrasar a emergência de uma infecção viral de hepatite c resistente ao tratamento, para diminuir o nível de resistência de uma infecção viral de hepatite c resistente ao tratamento, para diminuir a emergência de uma infecção viral de hepatite c resistente a hcv-796, para identificar um indivíduo com uma probabilidade diminuída de responder a uma terapia viral anti-hepatite c, para monitorar, diagnosticar ou prognosticar a infecção viral de hepatite c resistente ao tratamento em um paciente, para monitorar o curso de tratamento de uma infecção viral de hepatite c em um paciente, para prognosticar o desenvolvimento de um ainfecção viral de hepatite c resistente ao tratamento em um paciente, para monitorar a infecção viral de hepatite c em um paciente e para diagnosticar o desenvolvimento de uma infecção viral de hepatite ao tratamento em um paciente |
| AU2008214029B2 (en) | 2007-02-02 | 2014-01-30 | Globelmmune, Inc. | Methods for producing yeast-based vaccines |
| EP2134358A1 (en) | 2007-03-19 | 2009-12-23 | Globeimmune, Inc. | Compositions and methods for targeted ablation of mutational escape of targeted therapies for cancer |
| JP2012503011A (ja) | 2008-09-19 | 2012-02-02 | グローブイミューン，インコーポレイテッド | 慢性ｃ型肝炎ウイルス感染の免疫療法 |
-
2005
- 2005-10-18 CN CN2012101052485A patent/CN102614510A/zh active Pending
- 2005-10-18 WO PCT/US2005/037499 patent/WO2006044923A2/en not_active Ceased
- 2005-10-18 EP EP12157168.1A patent/EP2460533A3/en not_active Withdrawn
- 2005-10-18 CA CA002584562A patent/CA2584562A1/en not_active Abandoned
- 2005-10-18 JP JP2007537026A patent/JP2008516610A/ja active Pending
- 2005-10-18 CN CN2005800434620A patent/CN101437964B/zh not_active Expired - Fee Related
- 2005-10-18 SG SG200906938-6A patent/SG156652A1/en unknown
- 2005-10-18 AU AU2005295317A patent/AU2005295317B2/en not_active Ceased
- 2005-10-18 MX MX2007004662A patent/MX2007004662A/es active IP Right Grant
- 2005-10-18 BR BRPI0516356-0A patent/BRPI0516356A/pt not_active IP Right Cessation
- 2005-10-18 KR KR1020077011275A patent/KR20070068460A/ko not_active Ceased
- 2005-10-18 EP EP05812919.8A patent/EP1809773B1/en not_active Expired - Lifetime
-
2006
- 2006-12-31 US US11/618,834 patent/US7632511B2/en not_active Expired - Fee Related
- 2006-12-31 US US11/618,833 patent/US7625569B2/en not_active Expired - Fee Related
-
2007
- 2007-04-17 IL IL182609A patent/IL182609A/en not_active IP Right Cessation
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2008
- 2008-08-22 US US12/196,439 patent/US8007816B2/en not_active Expired - Lifetime
-
2009
- 2009-12-04 US US12/631,039 patent/US8388980B2/en not_active Expired - Fee Related
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2011
- 2011-09-30 JP JP2011216827A patent/JP2012034700A/ja active Pending
-
2013
- 2013-01-08 US US13/736,368 patent/US8821892B2/en not_active Expired - Fee Related
- 2013-08-05 JP JP2013162490A patent/JP2014012679A/ja not_active Withdrawn
Also Published As
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|---|---|
| EP1809773A4 (en) | 2009-12-23 |
| US8821892B2 (en) | 2014-09-02 |
| IL182609A (en) | 2014-04-30 |
| US8388980B2 (en) | 2013-03-05 |
| JP2012034700A (ja) | 2012-02-23 |
| AU2005295317B2 (en) | 2011-10-13 |
| US20080069831A1 (en) | 2008-03-20 |
| JP2014012679A (ja) | 2014-01-23 |
| SG156652A1 (en) | 2009-11-26 |
| US7625569B2 (en) | 2009-12-01 |
| US20080107671A1 (en) | 2008-05-08 |
| MX2007004662A (es) | 2007-11-23 |
| BRPI0516356A (pt) | 2008-09-02 |
| EP1809773B1 (en) | 2014-07-16 |
| US20130309265A1 (en) | 2013-11-21 |
| WO2006044923A2 (en) | 2006-04-27 |
| US20100150963A1 (en) | 2010-06-17 |
| US20090074805A1 (en) | 2009-03-19 |
| EP2460533A3 (en) | 2014-01-08 |
| EP1809773A2 (en) | 2007-07-25 |
| CN101437964B (zh) | 2012-06-13 |
| IL182609A0 (en) | 2007-07-24 |
| JP2008516610A (ja) | 2008-05-22 |
| WO2006044923A3 (en) | 2009-04-16 |
| EP2460533A2 (en) | 2012-06-06 |
| KR20070068460A (ko) | 2007-06-29 |
| HK1110358A1 (en) | 2008-07-11 |
| US7632511B2 (en) | 2009-12-15 |
| US8007816B2 (en) | 2011-08-30 |
| AU2005295317A1 (en) | 2006-04-27 |
| CN101437964A (zh) | 2009-05-20 |
| CN102614510A (zh) | 2012-08-01 |
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