CA2568352C - Methods of using il-1 antagonists to treat autoinflammatory disease - Google Patents
Methods of using il-1 antagonists to treat autoinflammatory disease Download PDFInfo
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- CA2568352C CA2568352C CA2568352A CA2568352A CA2568352C CA 2568352 C CA2568352 C CA 2568352C CA 2568352 A CA2568352 A CA 2568352A CA 2568352 A CA2568352 A CA 2568352A CA 2568352 C CA2568352 C CA 2568352C
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57702304P | 2004-06-04 | 2004-06-04 | |
| US60/577,023 | 2004-06-04 | ||
| PCT/US2005/019674 WO2005117945A1 (en) | 2004-06-04 | 2005-06-03 | Methods of using il-1 antagonists to treat autoinflammatory disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2568352A1 CA2568352A1 (en) | 2005-12-15 |
| CA2568352C true CA2568352C (en) | 2011-09-13 |
Family
ID=34972252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2568352A Expired - Fee Related CA2568352C (en) | 2004-06-04 | 2005-06-03 | Methods of using il-1 antagonists to treat autoinflammatory disease |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US7459426B2 (enExample) |
| EP (1) | EP1750746A1 (enExample) |
| JP (2) | JP5022216B2 (enExample) |
| CN (1) | CN1964737B (enExample) |
| AU (1) | AU2005249570B2 (enExample) |
| CA (1) | CA2568352C (enExample) |
| IL (1) | IL179512A0 (enExample) |
| MX (2) | MXPA06014126A (enExample) |
| WO (1) | WO2005117945A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1946734B (zh) | 2004-02-26 | 2012-07-18 | 贝勒研究院 | 系统性治疗关节炎的组合物和方法 |
| EP1778221A2 (en) * | 2004-05-27 | 2007-05-02 | Vertex Pharmaceuticals Incorporated | Ice inhibitors for the treatment of autoinflammatory diseases |
| US20060160737A1 (en) * | 2005-01-14 | 2006-07-20 | Allen Radin | Methods of using IL-1 antagonists to treat polymyalgia rheumatica and giant cell arteritis |
| AU2006306280B2 (en) * | 2005-10-26 | 2010-06-17 | Novartis Ag | Novel use of IL-1beta compounds |
| CN101378764A (zh) * | 2005-12-09 | 2009-03-04 | 贝勒研究院 | 通过血液白细胞微阵列分析对系统性红斑狼疮的诊断、预后和疾病发展的监测 |
| DK2124997T3 (da) * | 2006-10-20 | 2012-08-27 | Regeneron Pharma | Anvendelse af IL-1-antagonister til behandling af gigt og pseudogigt |
| US7632490B2 (en) | 2006-10-20 | 2009-12-15 | Regeneron Pharmaceuticals, Inc. | Use of IL-1 antagonists to treat gout |
| JP5272735B2 (ja) * | 2007-01-30 | 2013-08-28 | 国立大学法人 新潟大学 | 生物学的製剤 |
| WO2008112772A2 (en) * | 2007-03-14 | 2008-09-18 | Baylor Research Institute | Gene expression in peripheral blood mononuclear cells from children with diabetes |
| CA3213888A1 (en) * | 2007-05-29 | 2008-12-04 | Novartis Ag | New indications for anti-il-i-beta therapy |
| US20120315244A1 (en) | 2009-09-30 | 2012-12-13 | President And Fellows Of Harvard College | Methods for Modulation of Autophagy Through the Modulation of Autophagy-Inhibiting Gene Products |
| PT2582391T (pt) | 2010-06-18 | 2019-01-11 | Xbiotech Inc | Tratamento da artrite |
| SG187231A1 (en) | 2010-07-29 | 2013-02-28 | Eleven Biotherapeutics Inc | Chimeric il-1 receptor type i agonists and antagonists |
| CU23923B1 (es) * | 2010-11-12 | 2013-07-31 | Ct De Inmunología Molecular | Polipéptidos derivados de la il-2 con actividad agonista |
| SG11201406216XA (en) * | 2012-03-31 | 2015-03-30 | Pharm Cjsc Closed Joint Stock Company R | Osteoprotegerin derived composition and use thereof |
| CN103509100B (zh) * | 2012-06-15 | 2017-10-27 | 上海百迈博制药有限公司 | 一种白细胞介素‑1受体拮抗剂突变体 |
| WO2014035361A1 (en) * | 2012-08-26 | 2014-03-06 | R-PHARM, CJSC (Closed Joint Stock Company) | IL-1β INHIBITOR COMPOSITION AND USE THEREOF |
| SG11201507447PA (en) | 2013-03-13 | 2015-10-29 | Eleven Biotherapeutics Inc | Chimeric cytokine formulations for ocular delivery |
| JP2016520615A (ja) * | 2013-05-31 | 2016-07-14 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | アルツハイマー病を処置するためのｉｌ−１アンタゴニストを使用する方法 |
| WO2015027082A1 (en) * | 2013-08-22 | 2015-02-26 | Acceleron Pharma, Inc. | Tgf-beta receptor type ii variants and uses thereof |
| WO2015147789A1 (en) * | 2014-03-24 | 2015-10-01 | R-Pharm Overseas, Inc. | Human il 1-r1 derived inhibitor of il-1b |
| JP6565099B2 (ja) * | 2015-09-18 | 2019-08-28 | 国立大学法人 長崎大学 | 家族性地中海熱のバイオマーカー |
| SG10201913576RA (en) * | 2015-10-01 | 2020-02-27 | Heat Biologics Inc | Compositions and methods for adjoining type i and type ii extracellular domains as heterologous chimeric proteins |
| AU2016396182B2 (en) * | 2016-03-09 | 2021-01-21 | Valorisation Hsj, Limited Partnership | Methods for reducing perinatal morbidity and/or mortality |
| KR20190117579A (ko) * | 2017-02-16 | 2019-10-16 | 엑스바이오테크, 인크. | 화농성 한선염의 치료 |
| JP7170031B2 (ja) * | 2017-04-03 | 2022-11-11 | ウィスコンシン・アルムナイ・リサーチ・ファウンデーション | 生物学的に活性な分子を持続送達するためのミネラルコーティングされたマイクロ粒子 |
| JP2022524178A (ja) * | 2019-01-07 | 2022-04-28 | セルリス パルティシパソエス リミターダ | タンデム受容体ｃａｒにおける二重特異性と腫瘍マイクロ環境を変調する方法 |
| US20220409585A1 (en) * | 2019-11-07 | 2022-12-29 | Inflazome Limited | Treatment of autoinflammatory disorders |
| JP7072260B2 (ja) * | 2019-12-27 | 2022-05-20 | 国立大学法人愛媛大学 | マックル・ウェルズ症候群の治療用医薬組成物 |
| WO2021184128A1 (en) * | 2020-03-20 | 2021-09-23 | Institut De Cardiologie De Montreal | Methods of treating a coronavirus infection using colchicine |
| TW202210068A (zh) * | 2020-06-05 | 2022-03-16 | 美商雅力思提雅治療公司 | 用於治療家族性地中海型發熱病的cxcr-2抑制劑 |
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| US4980286A (en) | 1985-07-05 | 1990-12-25 | Whitehead Institute For Biomedical Research | In vivo introduction and expression of foreign genetic material in epithelial cells |
| US6472179B2 (en) | 1998-09-25 | 2002-10-29 | Regeneron Pharmaceuticals, Inc. | Receptor based antagonists and methods of making and using |
| US6927044B2 (en) * | 1998-09-25 | 2005-08-09 | Regeneron Pharmaceuticals, Inc. | IL-1 receptor based cytokine traps |
| WO2001087328A2 (en) * | 2000-05-12 | 2001-11-22 | Immunex Corporation | Interleukin-1 inhibitors in the treatment of diseases |
| DK2213685T3 (en) | 2002-09-06 | 2014-03-03 | Medarex Llc | Therapeutic anti-IL-1R1 monoclonal antibody |
| US20050129685A1 (en) * | 2003-09-18 | 2005-06-16 | Jingtai Cao | Use of IL-1 blockers to prevent corneal inflammation and neovascularization |
-
2005
- 2005-06-03 CA CA2568352A patent/CA2568352C/en not_active Expired - Fee Related
- 2005-06-03 JP JP2007515646A patent/JP5022216B2/ja not_active Expired - Fee Related
- 2005-06-03 AU AU2005249570A patent/AU2005249570B2/en not_active Ceased
- 2005-06-03 CN CN2005800182189A patent/CN1964737B/zh not_active Expired - Lifetime
- 2005-06-03 MX MXPA06014126A patent/MXPA06014126A/es active IP Right Grant
- 2005-06-03 WO PCT/US2005/019674 patent/WO2005117945A1/en not_active Ceased
- 2005-06-03 US US11/144,987 patent/US7459426B2/en active Active
- 2005-06-03 EP EP05758854A patent/EP1750746A1/en not_active Withdrawn
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2006
- 2006-11-23 IL IL179512A patent/IL179512A0/en unknown
- 2006-12-04 MX MX2011009567A patent/MX344967B/es unknown
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2008
- 2008-10-28 US US12/259,366 patent/US20090156492A1/en not_active Abandoned
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2011
- 2011-08-31 US US13/222,759 patent/US20110311537A1/en not_active Abandoned
- 2011-09-02 US US13/224,372 patent/US8414876B2/en not_active Expired - Fee Related
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2012
- 2012-01-25 JP JP2012012800A patent/JP2012111768A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN1964737A (zh) | 2007-05-16 |
| CN1964737B (zh) | 2011-04-20 |
| JP5022216B2 (ja) | 2012-09-12 |
| IL179512A0 (en) | 2007-05-15 |
| US20110318342A1 (en) | 2011-12-29 |
| AU2005249570B2 (en) | 2011-06-16 |
| US20050272655A1 (en) | 2005-12-08 |
| JP2008501716A (ja) | 2008-01-24 |
| WO2005117945A1 (en) | 2005-12-15 |
| US8414876B2 (en) | 2013-04-09 |
| MXPA06014126A (es) | 2007-07-18 |
| CA2568352A1 (en) | 2005-12-15 |
| AU2005249570A1 (en) | 2005-12-15 |
| US20110311537A1 (en) | 2011-12-22 |
| US7459426B2 (en) | 2008-12-02 |
| US20090156492A1 (en) | 2009-06-18 |
| HK1100837A1 (en) | 2007-09-28 |
| JP2012111768A (ja) | 2012-06-14 |
| EP1750746A1 (en) | 2007-02-14 |
| MX344967B (es) | 2017-01-12 |
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