AU2005249570B2 - Methods of using IL-1 antagonists to treat autoinflammatory disease - Google Patents
Methods of using IL-1 antagonists to treat autoinflammatory disease Download PDFInfo
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- AU2005249570B2 AU2005249570B2 AU2005249570A AU2005249570A AU2005249570B2 AU 2005249570 B2 AU2005249570 B2 AU 2005249570B2 AU 2005249570 A AU2005249570 A AU 2005249570A AU 2005249570 A AU2005249570 A AU 2005249570A AU 2005249570 B2 AU2005249570 B2 AU 2005249570B2
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- fusion protein
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Landscapes
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- Life Sciences & Earth Sciences (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| PCT/US2005/019674 WO2005117945A1 (en) | 2004-06-04 | 2005-06-03 | Methods of using il-1 antagonists to treat autoinflammatory disease |
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| WO2005082070A2 (en) | 2004-02-26 | 2005-09-09 | Baylor Research Institute | Compositions and methods for the systemic treatment of arthritis |
| US7531570B2 (en) * | 2004-05-27 | 2009-05-12 | Vertex Pharmaceuticals Incorporated | Treatment of diseases using ICE inhibitors |
| WO2006076673A2 (en) * | 2005-01-14 | 2006-07-20 | Regeneron Pharmaceuticals, Inc. | Use of il-i antagonists to treat polymyalgia rheumatica and giant cell arteritis |
| PL2848258T3 (pl) * | 2005-10-26 | 2018-06-29 | Novartis Ag | Leczenie rodzinnej gorączki śródziemnomorskiej przeciwciałami przeciwko IL-1beta |
| CN101374964B (zh) * | 2005-12-09 | 2013-07-17 | 贝勒研究院 | 外周血液白细胞转录模式的模块水平分析 |
| US7632490B2 (en) | 2006-10-20 | 2009-12-15 | Regeneron Pharmaceuticals, Inc. | Use of IL-1 antagonists to treat gout |
| BRPI0718469A2 (pt) * | 2006-10-20 | 2014-01-21 | Regeneron Pharma | Uso de um antagonista de interleucina 1 (il-1), método para tratar, inibir, ou melhorar pseudogota, uso de um ou mais agentes terapêuticos, e, produto. |
| WO2008093756A1 (ja) * | 2007-01-30 | 2008-08-07 | Niigata University | 生物学的製剤 |
| CA2718127A1 (en) * | 2007-03-14 | 2008-09-18 | Baylor Research Institute | Gene expression in peripheral blood mononuclear cells from children with diabetes |
| CA2993565C (en) * | 2007-05-29 | 2019-04-02 | Novartis Ag | New indications for anti-il-1-beta therapy |
| US20120301463A1 (en) | 2009-09-30 | 2012-11-29 | President And Fellows Of Harvard College | Methods for Modulation of Autophagy Through the Modulation of Autophagy-Enhancing Gene Products |
| JP6324720B2 (ja) | 2010-06-18 | 2018-05-16 | エックスバイオテク, インコーポレイテッドXbiotech, Inc. | 関節炎治療 |
| DK2598526T3 (en) | 2010-07-29 | 2018-11-19 | Eleven Biotherapeutics Inc | CHEMICAL IL-1 RECEPTOR TYPE-I AGONISTS AND ANTAGONISTS |
| CU23923B1 (es) * | 2010-11-12 | 2013-07-31 | Ct De Inmunología Molecular | Polipéptidos derivados de la il-2 con actividad agonista |
| SG11201406216XA (en) * | 2012-03-31 | 2015-03-30 | Pharm Cjsc Closed Joint Stock Company R | Osteoprotegerin derived composition and use thereof |
| CN103509100B (zh) * | 2012-06-15 | 2017-10-27 | 上海百迈博制药有限公司 | 一种白细胞介素‑1受体拮抗剂突变体 |
| WO2014035361A1 (en) * | 2012-08-26 | 2014-03-06 | R-PHARM, CJSC (Closed Joint Stock Company) | IL-1β INHIBITOR COMPOSITION AND USE THEREOF |
| CA2903706C (en) | 2013-03-13 | 2024-01-23 | Eleven Biotherapeutics, Inc. | Chimeric cytokine formulations for ocular delivery |
| JP2016520615A (ja) * | 2013-05-31 | 2016-07-14 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | アルツハイマー病を処置するためのｉｌ−１アンタゴニストを使用する方法 |
| CN105658672A (zh) * | 2013-08-22 | 2016-06-08 | 阿塞勒隆制药公司 | TGF-β受体II型变体及其用途 |
| US11155600B2 (en) * | 2014-03-24 | 2021-10-26 | R-Pharm Overseas, Inc. | Human IL1-R1 derived inhibitor of IL-1β |
| JP6565099B2 (ja) * | 2015-09-18 | 2019-08-28 | 国立大学法人 長崎大学 | 家族性地中海熱のバイオマーカー |
| CN116063566A (zh) * | 2015-10-01 | 2023-05-05 | 热生物制品有限公司 | 作为异源嵌合蛋白邻接i型和ii型胞外结构域的组合物和方法 |
| WO2017152254A1 (en) * | 2016-03-09 | 2017-09-14 | Chu Sainte-Justine | Methods for reducing perinatal morbidity and/or mortality |
| KR20190117579A (ko) * | 2017-02-16 | 2019-10-16 | 엑스바이오테크, 인크. | 화농성 한선염의 치료 |
| EP3606512A4 (en) * | 2017-04-03 | 2021-01-13 | Wisconsin Alumni Research Foundation | MINERAL COATED MICROPARTICLES INTENDED FOR THE PROLONGED DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES |
| WO2020142815A1 (en) * | 2019-01-07 | 2020-07-16 | Celluris Participações Ltda | Bispecific in tandem receptor car and method for modulating the tumoral microenvironment |
| JP2023501334A (ja) * | 2019-11-07 | 2023-01-18 | インフレイゾーム リミテッド | 自己炎症性疾患の処置 |
| JP7072260B2 (ja) * | 2019-12-27 | 2022-05-20 | 国立大学法人愛媛大学 | マックル・ウェルズ症候群の治療用医薬組成物 |
| WO2021184128A1 (en) * | 2020-03-20 | 2021-09-23 | Institut De Cardiologie De Montreal | Methods of treating a coronavirus infection using colchicine |
| EP4161499A1 (en) * | 2020-06-05 | 2023-04-12 | Aristea Therapeutics, Inc. | Use of a combination of colchicine and a cxcr-2 inhibitor for the treatment or prevention of familial mediterranean fever (fmf) and flare-ups thereof |
Citations (1)
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|---|---|---|---|---|
| US20030143697A1 (en) * | 1998-09-25 | 2003-07-31 | Neil Stahl | Receptor based antagonists and methods of making and using |
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| US4980286A (en) | 1985-07-05 | 1990-12-25 | Whitehead Institute For Biomedical Research | In vivo introduction and expression of foreign genetic material in epithelial cells |
| US6472179B2 (en) | 1998-09-25 | 2002-10-29 | Regeneron Pharmaceuticals, Inc. | Receptor based antagonists and methods of making and using |
| AU2001259758A1 (en) * | 2000-05-12 | 2001-11-26 | Immunex Corporation | Interleukin-1 inhibitors in the treatment of diseases |
| PL377091A1 (pl) * | 2002-09-06 | 2006-01-23 | Amgen, Inc. | Ludzkie monoklonalne przeciwciało przeciw-IL-1R1, o właściwościach terapeutycznych |
| US20050129685A1 (en) * | 2003-09-18 | 2005-06-16 | Jingtai Cao | Use of IL-1 blockers to prevent corneal inflammation and neovascularization |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030143697A1 (en) * | 1998-09-25 | 2003-07-31 | Neil Stahl | Receptor based antagonists and methods of making and using |
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|---|
| Economides, A. N. et al., Nature Medicine 2003, vol. 9, pages 47-52 * |
| Hawkins, P. N. et al., Arthritis and Rheumatism 2004, vol. 50, pages 607-612 * |
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| US8414876B2 (en) | 2013-04-09 |
| AU2005249570A1 (en) | 2005-12-15 |
| HK1100837A1 (en) | 2007-09-28 |
| CA2568352C (en) | 2011-09-13 |
| US20090156492A1 (en) | 2009-06-18 |
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