CA2567349C - Method of improving t cell receptors - Google Patents
Method of improving t cell receptors Download PDFInfo
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- CA2567349C CA2567349C CA2567349A CA2567349A CA2567349C CA 2567349 C CA2567349 C CA 2567349C CA 2567349 A CA2567349 A CA 2567349A CA 2567349 A CA2567349 A CA 2567349A CA 2567349 C CA2567349 C CA 2567349C
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- tcr
- tcrs
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- chain
- beta
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- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
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| GB9603507D0 (en) * | 1996-02-20 | 1996-04-17 | Isis Innovation | Antibody variants |
| WO1998039482A1 (en) * | 1997-03-07 | 1998-09-11 | Sunol Molecular Corporation | Fusion proteins comprising bacteriophage coat protein and a single-chain t cell receptor |
| US6759243B2 (en) * | 1998-01-20 | 2004-07-06 | Board Of Trustees Of The University Of Illinois | High affinity TCR proteins and methods |
| EP1118661A1 (en) * | 2000-01-13 | 2001-07-25 | Het Nederlands Kanker Instituut | T cell receptor libraries |
| PT1558643E (pt) * | 2002-11-09 | 2009-08-24 | Immunocore Ltd | Apresentação de um receptor das células t |
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- 2005-05-10 NZ NZ550815A patent/NZ550815A/en not_active IP Right Cessation
- 2005-05-10 EP EP05741949A patent/EP1756278B1/en not_active Expired - Lifetime
- 2005-05-10 CA CA2567349A patent/CA2567349C/en not_active Expired - Lifetime
- 2005-05-10 WO PCT/GB2005/001781 patent/WO2005114215A2/en not_active Ceased
- 2005-05-10 DE DE602005009825T patent/DE602005009825D1/de not_active Expired - Lifetime
- 2005-05-10 AT AT05741949T patent/ATE408684T1/de not_active IP Right Cessation
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| EP1756278B1 (en) | 2008-09-17 |
| JP2007537743A (ja) | 2007-12-27 |
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| US7608410B2 (en) | 2009-10-27 |
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| HK1105995A1 (en) | 2008-02-29 |
| ATE408684T1 (de) | 2008-10-15 |
| WO2005114215A2 (en) | 2005-12-01 |
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| AU2005246073A1 (en) | 2005-12-01 |
| CA2567349A1 (en) | 2005-12-01 |
| NZ550815A (en) | 2009-04-30 |
| JP4972549B2 (ja) | 2012-07-11 |
| WO2005114215A3 (en) | 2006-03-16 |
| US20090054257A1 (en) | 2009-02-26 |
| WO2005114215A9 (en) | 2006-07-20 |
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