CA2560108A1 - Acides nucleiques immunostimulateurs destines a induire des reactions d'il-10 - Google Patents
Acides nucleiques immunostimulateurs destines a induire des reactions d'il-10 Download PDFInfo
- Publication number
- CA2560108A1 CA2560108A1 CA002560108A CA2560108A CA2560108A1 CA 2560108 A1 CA2560108 A1 CA 2560108A1 CA 002560108 A CA002560108 A CA 002560108A CA 2560108 A CA2560108 A CA 2560108A CA 2560108 A1 CA2560108 A1 CA 2560108A1
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- Prior art keywords
- oligonucleotide
- subject
- cytosine
- modified
- nucleotide
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US55895104P | 2004-04-02 | 2004-04-02 | |
US60/558,951 | 2004-04-02 | ||
PCT/US2005/011827 WO2005111057A2 (fr) | 2004-04-02 | 2005-04-04 | Acides nucleiques immunostimulateurs destines a induire des reactions d'il-10 |
Publications (1)
Publication Number | Publication Date |
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CA2560108A1 true CA2560108A1 (fr) | 2005-11-24 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CA002560108A Abandoned CA2560108A1 (fr) | 2004-04-02 | 2005-04-04 | Acides nucleiques immunostimulateurs destines a induire des reactions d'il-10 |
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US (1) | US20060019916A1 (fr) |
EP (1) | EP1730281A2 (fr) |
JP (1) | JP2007531746A (fr) |
AU (2) | AU2005243250A1 (fr) |
CA (1) | CA2560108A1 (fr) |
WO (1) | WO2005111057A2 (fr) |
Families Citing this family (68)
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US6727230B1 (en) * | 1994-03-25 | 2004-04-27 | Coley Pharmaceutical Group, Inc. | Immune stimulation by phosphorothioate oligonucleotide analogs |
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US7935675B1 (en) * | 1994-07-15 | 2011-05-03 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
US20030026782A1 (en) * | 1995-02-07 | 2003-02-06 | Arthur M. Krieg | Immunomodulatory oligonucleotides |
US6207646B1 (en) * | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
US6239116B1 (en) * | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
EP0855184A1 (fr) * | 1997-01-23 | 1998-07-29 | Grayson B. Dr. Lipford | Composition pharmaceutique comprenant un polynucléotide et un antigène notamment pour la vaccination |
US6406705B1 (en) * | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
DE69935507T2 (de) * | 1998-04-03 | 2007-12-06 | University Of Iowa Research Foundation | Verfahren und produkte zur stimulierung des immunsystems mittels immunotherapeutischer oligonukleotide und zytokine |
EP1078053B1 (fr) * | 1998-05-14 | 2005-09-28 | Coley Pharmaceutical GmbH | PROCEDES DE REGULATION DE L'HEMATOPOIESE AU MOYEN D'OLIGONUCLEOTIDES A CpG |
EP1077722B1 (fr) * | 1998-05-22 | 2006-08-09 | Ottawa Health Research Institute | Methodes et produits permettant d'induire une immunite au niveau des muqueuses |
US20030022854A1 (en) | 1998-06-25 | 2003-01-30 | Dow Steven W. | Vaccines using nucleic acid-lipid complexes |
US6693086B1 (en) * | 1998-06-25 | 2004-02-17 | National Jewish Medical And Research Center | Systemic immune activation method using nucleic acid-lipid complexes |
US7776343B1 (en) * | 1999-02-17 | 2010-08-17 | Csl Limited | Immunogenic complexes and methods relating thereto |
US6949520B1 (en) * | 1999-09-27 | 2005-09-27 | Coley Pharmaceutical Group, Inc. | Methods related to immunostimulatory nucleic acid-induced interferon |
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US20040131628A1 (en) * | 2000-03-08 | 2004-07-08 | Bratzler Robert L. | Nucleic acids for the treatment of disorders associated with microorganisms |
SI1296714T1 (sl) * | 2000-06-22 | 2010-01-29 | S For Entpr University Of Iowa | Kombinacija CpG-ja in protiteles, usmerjenih proti CD19, CD20, CD22 ali CD40 za zdravljenje ali preprečevanje raka |
KR100917101B1 (ko) * | 2000-08-04 | 2009-09-15 | 도요 보세키 가부시키가이샤 | 플렉시블 금속적층체 및 그 제조방법 |
CA2419894A1 (fr) * | 2000-09-15 | 2002-03-21 | Coley Pharmaceutical Gmbh | Procede de criblage a haut rendement d'immuno-agoniste/antagoniste base sur cpg |
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EP1446162B1 (fr) * | 2001-08-17 | 2008-10-15 | Coley Pharmaceutical GmbH | Oligonucleotides immunostimulateurs a motif combine possedant une activite accrue |
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US7605138B2 (en) * | 2002-07-03 | 2009-10-20 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
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US7569553B2 (en) * | 2002-07-03 | 2009-08-04 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
US7807803B2 (en) | 2002-07-03 | 2010-10-05 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
US20040053880A1 (en) * | 2002-07-03 | 2004-03-18 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
AR040996A1 (es) | 2002-08-19 | 2005-04-27 | Coley Pharm Group Inc | Acidos nucleicos inmunoestimuladores |
JP2006515277A (ja) * | 2002-10-29 | 2006-05-25 | コーリー ファーマシューティカル グループ, リミテッド | C型肝炎ウィルス感染の処置および予防に関する方法および製品 |
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JP2007526253A (ja) * | 2004-02-19 | 2007-09-13 | コーリー ファーマシューティカル グループ,インコーポレイテッド | 免疫刺激性ウイルスrnaオリゴヌクレオチド |
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CN101310019A (zh) * | 2005-09-16 | 2008-11-19 | 科利制药公司 | 具有磷酸二酯主链的免疫刺激性单链核糖核酸 |
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-
2005
- 2005-04-04 US US11/099,683 patent/US20060019916A1/en not_active Abandoned
- 2005-04-04 AU AU2005243250A patent/AU2005243250A1/en not_active Abandoned
- 2005-04-04 WO PCT/US2005/011827 patent/WO2005111057A2/fr not_active Application Discontinuation
- 2005-04-04 CA CA002560108A patent/CA2560108A1/fr not_active Abandoned
- 2005-04-04 EP EP05777310A patent/EP1730281A2/fr not_active Withdrawn
- 2005-04-04 JP JP2007506379A patent/JP2007531746A/ja active Pending
-
2010
- 2010-07-08 AU AU2010202893A patent/AU2010202893A1/en not_active Ceased
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WO2005111057A3 (fr) | 2006-07-27 |
AU2010202893A1 (en) | 2010-07-29 |
WO2005111057A2 (fr) | 2005-11-24 |
EP1730281A2 (fr) | 2006-12-13 |
US20060019916A1 (en) | 2006-01-26 |
AU2005243250A1 (en) | 2005-11-24 |
JP2007531746A (ja) | 2007-11-08 |
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