CA2542881A1 - Anticorps possedant un ratio taux de fucose / taux de galactose optimise - Google Patents
Anticorps possedant un ratio taux de fucose / taux de galactose optimise Download PDFInfo
- Publication number
- CA2542881A1 CA2542881A1 CA002542881A CA2542881A CA2542881A1 CA 2542881 A1 CA2542881 A1 CA 2542881A1 CA 002542881 A CA002542881 A CA 002542881A CA 2542881 A CA2542881 A CA 2542881A CA 2542881 A1 CA2542881 A1 CA 2542881A1
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- Prior art keywords
- antibody
- antibodies
- activity
- fucose
- galactose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0312229 | 2003-10-20 | ||
| FR0312229A FR2861080B1 (fr) | 2003-10-20 | 2003-10-20 | Anticorps presentant un taux de fucose et de galactose optimise |
| PCT/FR2004/002686 WO2005040221A1 (fr) | 2003-10-20 | 2004-10-20 | Correlation du ratio taux de fucose / taux de galactose d’anticorps anti rhesus d et anti hla-dr avec l’activite adcc |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2542881A1 true CA2542881A1 (fr) | 2005-05-06 |
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ID=34385294
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002542881A Abandoned CA2542881A1 (fr) | 2003-10-20 | 2004-10-20 | Anticorps possedant un ratio taux de fucose / taux de galactose optimise |
Country Status (9)
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| FR (1) | FR2861080B1 (enExample) |
| IL (1) | IL174896A0 (enExample) |
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| FR2892724B1 (fr) * | 2005-11-02 | 2008-01-04 | Lab Francais Du Fractionnement | Anticorps cytotoxiques diriges contre des anticorps inhibiteurs du facteur viii. |
| US7846724B2 (en) | 2006-04-11 | 2010-12-07 | Hoffmann-La Roche Inc. | Method for selecting CHO cell for production of glycosylated antibodies |
| AU2013203482B2 (en) * | 2006-09-10 | 2015-08-27 | Glycotope Gmbh | Fully human high yield production system for improved antibodies and proteins |
| HRP20150307T1 (hr) * | 2006-09-10 | 2015-04-24 | Glycotope Gmbh | Upotreba ljudskih stanica podrijetlom iz ljudske leukemije za eksprimiranje protutijela |
| US7846434B2 (en) * | 2006-10-24 | 2010-12-07 | Trubion Pharmaceuticals, Inc. | Materials and methods for improved immunoglycoproteins |
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| US20080227669A1 (en) * | 2007-03-12 | 2008-09-18 | Halliburton Energy Services, Inc. | Corrosion-inhibiting additives, treatment fluids, and associated methods |
| EP1995309A1 (en) * | 2007-05-21 | 2008-11-26 | Vivalis | Recombinant protein production in avian EBx® cells |
| US8080415B2 (en) | 2008-09-26 | 2011-12-20 | Eureka Therapeutics, Inc. | Modified host cells and uses thereof |
| AU2010233994A1 (en) * | 2009-04-07 | 2011-09-22 | Roche Glycart Ag | Bispecific anti-ErbB-3/anti-c-Met antibodies |
| HUE033758T2 (en) | 2009-10-26 | 2017-12-28 | Hoffmann La Roche | A method for producing glycosylated immunoglobulin |
| EP2374816B1 (en) | 2010-04-07 | 2016-09-28 | Agency For Science, Technology And Research | Binding molecules against Chikungunya virus and uses thereof |
| WO2011124635A1 (en) | 2010-04-07 | 2011-10-13 | Humalys | Binding molecules against chikungunya virus and uses thereof |
| EP2409993A1 (en) | 2010-07-19 | 2012-01-25 | International-Drug-Development-Biotech | Anti-CD19 antibody having ADCC function with improved glycosylation profile |
| EP2409712A1 (en) | 2010-07-19 | 2012-01-25 | International-Drug-Development-Biotech | Anti-CD19 antibody having ADCC and CDC functions and improved glycosylation profile |
| EP2409989A1 (en) | 2010-07-19 | 2012-01-25 | International-Drug-Development-Biotech | Method to improve glycosylation profile for antibody |
| JPWO2012105699A1 (ja) * | 2011-02-03 | 2014-07-03 | 株式会社イーベック | 補体依存性生物活性の高い抗体の産生法 |
| EP2702077A2 (en) | 2011-04-27 | 2014-03-05 | AbbVie Inc. | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
| BR112014003110A2 (pt) * | 2011-08-10 | 2018-10-09 | Lab Francais Du Fractionnement | composição, método para produção de uma população altamente galactosilada de anticorpos, células epiteliais de glândula mamária e mamífero não humano tramsgênico |
| BR112014004065A2 (pt) | 2011-08-22 | 2017-03-14 | Glycotope Gmbh | micro-organismos carregando um antígeno de tumor |
| WO2013158273A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Methods to modulate c-terminal lysine variant distribution |
| WO2013158279A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Protein purification methods to reduce acidic species |
| US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
| US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
| AR094781A1 (es) * | 2013-02-13 | 2015-08-26 | Laboratoire Français Du Fractionnement Et Des Biotechnologies | Anticuerpos anti-her2 (receptor 2 del factor de crecimiento epidérmico humano) altamente galactosilados y sus usos |
| BR112015019341A2 (pt) * | 2013-02-13 | 2017-08-22 | Lab Francais Du Fractionnement | Anticorpo anti-tnf-alfa, composição que compreende o anticorpo, método para produzir uma população de anticorpos, células epiteliais da glândula mamária, mamífero não humano transgênico, e, composição de anticorpo anti-tnf monoclonal |
| EP2956003A2 (en) | 2013-02-13 | 2015-12-23 | Laboratoire Français du Fractionnement et des Biotechnologies | Proteins with modified glycosylation and methods of production thereof |
| CA2905010A1 (en) | 2013-03-12 | 2014-09-18 | Abbvie Inc. | Human antibodies that bind human tnf-alpha and methods of preparing the same |
| US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
| WO2014151878A2 (en) | 2013-03-14 | 2014-09-25 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides |
| US9598667B2 (en) | 2013-10-04 | 2017-03-21 | Abbvie Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
| US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
| US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
| US20150139988A1 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
| CN114181312A (zh) * | 2014-09-10 | 2022-03-15 | 豪夫迈·罗氏有限公司 | 半乳糖改造的免疫球蛋白1抗体 |
| FR3035879B1 (fr) * | 2015-05-07 | 2025-02-28 | Lab Francais Du Fractionnement | Mutants fc a activite fonctionnelle modifiee |
| FR3038517B1 (fr) | 2015-07-06 | 2020-02-28 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Utilisation de fragments fc modifies en immunotherapie |
| EP3410849B1 (en) | 2016-02-05 | 2023-07-05 | Institut Pasteur | Use of inhibitors of adam12 as adjuvants in tumor therapies |
| CN110945028B (zh) | 2017-07-10 | 2023-09-08 | 国际药物发展生物技术公司 | 用非岩藻糖基化促凋亡抗cd19抗体与抗cd20抗体或化疗剂联合治疗b细胞恶性肿瘤 |
| EP3508499A1 (en) | 2018-01-08 | 2019-07-10 | iOmx Therapeutics AG | Antibodies targeting, and other modulators of, an immunoglobulin gene associated with resistance against anti-tumour immune responses, and uses thereof |
| BR112020023373A2 (pt) | 2018-05-18 | 2021-02-09 | Daiichi Sankyo Company, Limited | conjugado, composição, e, uso de um conjugado ou de uma composição |
| US20220372138A1 (en) | 2019-07-05 | 2022-11-24 | Iomx Therapeutics Ag | Antibodies binding igc2 of igsf11 (vsig3) and uses thereof |
| EP3822288A1 (en) | 2019-11-18 | 2021-05-19 | Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts | Antibodies targeting, and other modulators of, the cd276 antigen, and uses thereof |
| EP4175668A1 (en) | 2020-07-06 | 2023-05-10 | iOmx Therapeutics AG | Antibodies binding igv of igsf11 (vsig3) and uses thereof |
| EP4491230A1 (en) | 2023-07-14 | 2025-01-15 | iOmx Therapeutics AG | Cross-specific antigen binding proteins (abp) targeting leukocyte immunoglobulin-like receptor subfamily b1 (lilrb1) and lilrb2, combinations and uses thereof |
| IL321673A (en) | 2022-12-23 | 2025-08-01 | Iomx Therapeutics Ag | LILRB1 and LILRB2 antigen-binding cross-specific proteins, their combinations and uses |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0316463A1 (en) * | 1987-11-13 | 1989-05-24 | Northwestern University | Murine hybridoma lym-1 and diagnostic antibody produced thereby |
| SE9203479L (sv) * | 1992-01-20 | 1993-07-21 | Rso Corp | Saett och anordning vid elektronisk identifiering |
| FR2776096B1 (fr) * | 1998-03-12 | 2000-06-23 | Commissariat Energie Atomique | Procede et systeme de lecture d'un ensemble dynamique d'etiquettes portant des codes d'identification distincts |
| FR2805637B1 (fr) * | 2000-02-25 | 2002-12-13 | Commissariat Energie Atomique | Procede de lecture d'etiquettes electroniques par identification simultanee de leur code |
| FR2807767B1 (fr) * | 2000-04-12 | 2005-01-14 | Lab Francais Du Fractionnement | Anticorps monoclonaux anti-d |
| US6946292B2 (en) * | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
| WO2004047000A2 (en) * | 2002-11-15 | 2004-06-03 | Sensitech Inc. | Rf identification tag for communicating condition information associated with an item |
| FR2859843B1 (fr) * | 2003-09-16 | 2005-12-23 | Commissariat Energie Atomique | Dispositif adressable par radiofrequence, systeme comportant une pluralite de tels dispositifs agences dans l'espace et procede d'adressage par activation d'un mode transparent |
-
2003
- 2003-10-20 FR FR0312229A patent/FR2861080B1/fr not_active Expired - Fee Related
-
2004
- 2004-10-20 AU AU2004283924A patent/AU2004283924B2/en not_active Ceased
- 2004-10-20 BR BRPI0415565-3A patent/BRPI0415565A/pt not_active Application Discontinuation
- 2004-10-20 WO PCT/FR2004/002686 patent/WO2005040221A1/fr not_active Ceased
- 2004-10-20 CA CA002542881A patent/CA2542881A1/fr not_active Abandoned
- 2004-10-20 JP JP2006534807A patent/JP2007533299A/ja active Pending
- 2004-10-20 US US10/575,333 patent/US20070015239A1/en not_active Abandoned
- 2004-10-20 EP EP04805250A patent/EP1675873A1/fr not_active Withdrawn
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2006
- 2006-04-10 IL IL174896A patent/IL174896A0/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005040221A1 (fr) | 2005-05-06 |
| AU2004283924B2 (en) | 2010-12-02 |
| BRPI0415565A (pt) | 2007-01-02 |
| IL174896A0 (en) | 2006-08-20 |
| EP1675873A1 (fr) | 2006-07-05 |
| FR2861080A1 (fr) | 2005-04-22 |
| FR2861080B1 (fr) | 2006-02-17 |
| JP2007533299A (ja) | 2007-11-22 |
| US20070015239A1 (en) | 2007-01-18 |
| AU2004283924A1 (en) | 2005-05-06 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20131022 |