CA2540771A1 - Nanoparticulate therapeutic biologically active agents - Google Patents
Nanoparticulate therapeutic biologically active agents Download PDFInfo
- Publication number
- CA2540771A1 CA2540771A1 CA002540771A CA2540771A CA2540771A1 CA 2540771 A1 CA2540771 A1 CA 2540771A1 CA 002540771 A CA002540771 A CA 002540771A CA 2540771 A CA2540771 A CA 2540771A CA 2540771 A1 CA2540771 A1 CA 2540771A1
- Authority
- CA
- Canada
- Prior art keywords
- particles
- biologically active
- nonsolvent
- polymer
- insulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50741303P | 2003-09-30 | 2003-09-30 | |
| US60/507,413 | 2003-09-30 | ||
| PCT/US2004/032271 WO2005032511A2 (en) | 2003-09-30 | 2004-09-30 | Nanoparticulate therapeutic biologically active agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2540771A1 true CA2540771A1 (en) | 2005-04-14 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002540771A Abandoned CA2540771A1 (en) | 2003-09-30 | 2004-09-30 | Nanoparticulate therapeutic biologically active agents |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050181059A1 (https=) |
| EP (1) | EP1675571A2 (https=) |
| JP (1) | JP2007507527A (https=) |
| AU (1) | AU2004277419B2 (https=) |
| CA (1) | CA2540771A1 (https=) |
| WO (1) | WO2005032511A2 (https=) |
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| US20050186183A1 (en) * | 2003-12-08 | 2005-08-25 | Deangelo Joseph | Stabilized products, processes and devices for preparing same |
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| EP2012753A2 (en) * | 2006-04-28 | 2009-01-14 | Schering Corporation | Process for the precipitation and isolation of 6,6-dimethyl-3-aza-bicyclo [3.1.0]hexane-amide compounds by controlled precipitation and pharmaceutical formulations containing same |
| US20090311295A1 (en) * | 2006-05-12 | 2009-12-17 | Edith Mathiowitz | Particles with high uniform loading of nanoparticles and methods of preparation thereof |
| WO2008144365A2 (en) * | 2007-05-17 | 2008-11-27 | Novartis Ag | Method for making dry powder compositions containing ds-rna based on supercritical fluid technology |
| US9504274B2 (en) | 2009-01-27 | 2016-11-29 | Frito-Lay North America, Inc. | Methods of flavor encapsulation and matrix-assisted concentration of aqueous foods and products produced therefrom |
| US20100189845A1 (en) * | 2009-01-27 | 2010-07-29 | Frito-Lay North America Inc. | Flavor Encapsulation and Method Thereof |
| WO2010102065A1 (en) | 2009-03-05 | 2010-09-10 | Bend Research, Inc. | Pharmaceutical compositions of dextran polymer derivatives |
| US20100310726A1 (en) * | 2009-06-05 | 2010-12-09 | Kraft Foods Global Brands Llc | Novel Preparation of an Enteric Release System |
| US20100307542A1 (en) * | 2009-06-05 | 2010-12-09 | Kraft Foods Global Brands Llc | Method of Reducing Surface Oil on Encapsulated Material |
| US9968564B2 (en) * | 2009-06-05 | 2018-05-15 | Intercontinental Great Brands Llc | Delivery of functional compounds |
| US8859003B2 (en) * | 2009-06-05 | 2014-10-14 | Intercontinental Great Brands Llc | Preparation of an enteric release system |
| US8682440B2 (en) | 2009-08-03 | 2014-03-25 | Incube Labs, Llc | Swallowable capsule and method for stimulating incretin production within the intestinal tract |
| US8721620B2 (en) | 2009-12-24 | 2014-05-13 | Rani Therapeutics, Llc | Swallowable drug delivery device and methods of drug delivery |
| US8815294B2 (en) | 2010-09-03 | 2014-08-26 | Bend Research, Inc. | Pharmaceutical compositions of dextran polymer derivatives and a carrier material |
| CN103298453A (zh) * | 2010-09-30 | 2013-09-11 | 赢创有限公司 | 制备低残留溶剂微粒的乳化法 |
| CA2813301A1 (en) * | 2010-09-30 | 2012-04-05 | Evonik Corporation | Method for removing residual organic solvent from microparticles |
| US20120148675A1 (en) * | 2010-12-10 | 2012-06-14 | Basawaraj Chickmath | Testosterone undecanoate compositions |
| US9402807B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9629799B2 (en) | 2010-12-23 | 2017-04-25 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10639272B2 (en) | 2010-12-23 | 2020-05-05 | Rani Therapeutics, Llc | Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8734429B2 (en) | 2010-12-23 | 2014-05-27 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
| US9861683B2 (en) | 2010-12-23 | 2018-01-09 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8809269B2 (en) | 2010-12-23 | 2014-08-19 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9402806B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9259386B2 (en) | 2010-12-23 | 2016-02-16 | Rani Therapeutics, Llc | Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8969293B2 (en) | 2010-12-23 | 2015-03-03 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising exenatide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9415004B2 (en) | 2010-12-23 | 2016-08-16 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9283179B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | GnRH preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9284367B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8980822B2 (en) | 2010-12-23 | 2015-03-17 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising pramlintide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8846040B2 (en) | 2010-12-23 | 2014-09-30 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising etanercept for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9084727B2 (en) | 2011-05-10 | 2015-07-21 | Bend Research, Inc. | Methods and compositions for maintaining active agents in intra-articular spaces |
| TWI425979B (zh) * | 2011-10-28 | 2014-02-11 | Univ Ming Chi Technology | 次微米級微粒的製備方法 |
| US8859005B2 (en) | 2012-12-03 | 2014-10-14 | Intercontinental Great Brands Llc | Enteric delivery of functional ingredients suitable for hot comestible applications |
| BR122020001306B1 (pt) | 2013-05-31 | 2022-11-29 | Newleaf Symbiotics, Inc | Métodos e composições de fermentação bacteriana |
| CN106794156B (zh) * | 2014-07-08 | 2021-03-09 | 美药星制药股份有限公司 | 微粒化胰岛素、微粒化胰岛素类似物及其制备方法 |
| US10322168B2 (en) | 2016-01-07 | 2019-06-18 | Amphastar Pharmaceuticals, Inc. | High-purity inhalable particles of insulin and insulin analogues, and high-efficiency methods of manufacturing the same |
| US11491114B2 (en) * | 2016-10-12 | 2022-11-08 | Curioralrx, Llc | Formulations for enteric delivery of therapeutic agents |
| US20210290733A1 (en) * | 2018-07-16 | 2021-09-23 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Injectable micronized human insulin |
| WO2024011218A1 (en) * | 2022-07-08 | 2024-01-11 | Brown University | Polymeric nanoparticles for long acting delivery of a peptide and methods of making and using thereof |
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| US3460631A (en) * | 1966-11-14 | 1969-08-12 | Friesen Ind Inc | High clearance wheel mounted spring-tooth harrow |
| US3483951A (en) * | 1968-12-06 | 1969-12-16 | Wisconsin Alumni Res Found | Self-optimizing vibration dampers |
| US3828860A (en) * | 1973-02-28 | 1974-08-13 | Kewanne Machinery & Conveyor C | Agricultural implement with foldable wings |
| US4107288A (en) * | 1974-09-18 | 1978-08-15 | Pharmaceutical Society Of Victoria | Injectable compositions, nanoparticles useful therein, and process of manufacturing same |
| US4151273A (en) * | 1974-10-31 | 1979-04-24 | The Regents Of The University Of California | Increasing the absorption rate of insoluble drugs |
| US4050522A (en) * | 1976-03-29 | 1977-09-27 | J. I. Case Company | Multi-section harrow assembly |
| CA1145607A (en) * | 1979-06-19 | 1983-05-03 | Malcolm F. Ferber | Agricultural implement carriage system |
| IT1130924B (it) * | 1980-03-06 | 1986-06-18 | Secifarma Spa | Procedimento per la preparazione di spironolattone micronizzato |
| US4384975A (en) * | 1980-06-13 | 1983-05-24 | Sandoz, Inc. | Process for preparation of microspheres |
| DE3744329A1 (de) * | 1987-12-28 | 1989-07-06 | Schwarz Pharma Gmbh | Verfahren zur herstellung einer mindestens einen wirkstoff und einen traeger umfassenden zubereitung |
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| US5639441A (en) * | 1992-03-06 | 1997-06-17 | Board Of Regents Of University Of Colorado | Methods for fine particle formation |
| IS1796B (is) * | 1993-06-24 | 2001-12-31 | Ab Astra | Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband |
| GB9313642D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
| DE4329446A1 (de) * | 1993-09-01 | 1995-03-02 | Basf Ag | Verfahren zur Herstellung von feinteiligen Farb- oder Wirkstoffzubereitungen |
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| US6143211A (en) * | 1995-07-21 | 2000-11-07 | Brown University Foundation | Process for preparing microparticles through phase inversion phenomena |
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| US5874029A (en) * | 1996-10-09 | 1999-02-23 | The University Of Kansas | Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent |
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| US5800834A (en) * | 1996-06-10 | 1998-09-01 | Spireas; Spiridon | Liquisolid systems and methods of preparing same |
| AUPR197000A0 (en) * | 2000-12-08 | 2001-01-11 | Unisearch Limited | Synthesis of small particles |
| JP2005506951A (ja) * | 2000-12-29 | 2005-03-10 | ペストカ バイオメディカル ラボラトリーズ インコーポレイテッド | 高分子のための制御放出系 |
| GB0102075D0 (en) * | 2001-01-26 | 2001-03-14 | Astrazeneca Ab | Process |
| SG126676A1 (en) * | 2001-05-09 | 2007-01-30 | Nanomaterials Tech Pte Ltd | Process for the controlled production of organic particles |
| CA2469718A1 (en) * | 2001-12-10 | 2003-06-19 | Spherics, Inc. | Methods and products useful in the formation and isolation of microparticles |
-
2004
- 2004-09-30 AU AU2004277419A patent/AU2004277419B2/en not_active Ceased
- 2004-09-30 JP JP2006534125A patent/JP2007507527A/ja active Pending
- 2004-09-30 EP EP04785328A patent/EP1675571A2/en not_active Withdrawn
- 2004-09-30 WO PCT/US2004/032271 patent/WO2005032511A2/en not_active Ceased
- 2004-09-30 CA CA002540771A patent/CA2540771A1/en not_active Abandoned
- 2004-09-30 US US10/954,423 patent/US20050181059A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004277419A1 (en) | 2005-04-14 |
| WO2005032511A2 (en) | 2005-04-14 |
| US20050181059A1 (en) | 2005-08-18 |
| JP2007507527A (ja) | 2007-03-29 |
| AU2004277419B2 (en) | 2007-10-11 |
| EP1675571A2 (en) | 2006-07-05 |
| WO2005032511A3 (en) | 2005-05-19 |
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| EEER | Examination request | ||
| FZDE | Discontinued |