ATE146359T1 - Verbessertes verfahren zur herstellung von mikronisierter polypeptidarzneimitteln - Google Patents

Verbessertes verfahren zur herstellung von mikronisierter polypeptidarzneimitteln

Info

Publication number
ATE146359T1
ATE146359T1 AT93903517T AT93903517T ATE146359T1 AT E146359 T1 ATE146359 T1 AT E146359T1 AT 93903517 T AT93903517 T AT 93903517T AT 93903517 T AT93903517 T AT 93903517T AT E146359 T1 ATE146359 T1 AT E146359T1
Authority
AT
Austria
Prior art keywords
milling
drug
polypeptide drugs
drugs
stabilizers
Prior art date
Application number
AT93903517T
Other languages
English (en)
Inventor
Robert M Platz
Anna Ip
Clyde L Witham
Original Assignee
Stanford Res Inst Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stanford Res Inst Int filed Critical Stanford Res Inst Int
Application granted granted Critical
Publication of ATE146359T1 publication Critical patent/ATE146359T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
AT93903517T 1992-01-21 1993-01-20 Verbessertes verfahren zur herstellung von mikronisierter polypeptidarzneimitteln ATE146359T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82321892A 1992-01-21 1992-01-21

Publications (1)

Publication Number Publication Date
ATE146359T1 true ATE146359T1 (de) 1997-01-15

Family

ID=25238119

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93903517T ATE146359T1 (de) 1992-01-21 1993-01-20 Verbessertes verfahren zur herstellung von mikronisierter polypeptidarzneimitteln

Country Status (7)

Country Link
US (1) US5354562A (de)
EP (1) EP0621774B1 (de)
JP (1) JPH07503154A (de)
AT (1) ATE146359T1 (de)
CA (1) CA2127877A1 (de)
DE (1) DE69306755T2 (de)
WO (1) WO1993013752A1 (de)

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Also Published As

Publication number Publication date
DE69306755T2 (de) 1997-04-10
DE69306755D1 (de) 1997-01-30
US5354562A (en) 1994-10-11
CA2127877A1 (en) 1993-07-22
EP0621774A1 (de) 1994-11-02
JPH07503154A (ja) 1995-04-06
WO1993013752A1 (en) 1993-07-22
EP0621774B1 (de) 1996-12-18

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