CA2535401C - Composition emulsionnee contenant de la dapsone - Google Patents

Composition emulsionnee contenant de la dapsone Download PDF

Info

Publication number
CA2535401C
CA2535401C CA2535401A CA2535401A CA2535401C CA 2535401 C CA2535401 C CA 2535401C CA 2535401 A CA2535401 A CA 2535401A CA 2535401 A CA2535401 A CA 2535401A CA 2535401 C CA2535401 C CA 2535401C
Authority
CA
Canada
Prior art keywords
percent
dapsone
emulsive
emulsive composition
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2535401A
Other languages
English (en)
Other versions
CA2535401A1 (fr
Inventor
Robert William Lathrop
David W. Osborne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Sales LLC
Original Assignee
Allergan Sales LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Sales LLC filed Critical Allergan Sales LLC
Publication of CA2535401A1 publication Critical patent/CA2535401A1/fr
Application granted granted Critical
Publication of CA2535401C publication Critical patent/CA2535401C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

La présente invention a trait à un composition topique émulsionnée contenant de la dapsone ou de son dérivé. La composition selon l'invention comporte des émollients et de la dapsone ou son dérivé dans une émulsion stable. La stabilité est réalisée grâce à l'utilisation d'une combinaison de certains mélanges de tensioactifs et à d'un activateur assurant une solubilité de la dapsone.
CA2535401A 2003-08-13 2004-08-13 Composition emulsionnee contenant de la dapsone Active CA2535401C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49491203P 2003-08-13 2003-08-13
US60/494,912 2003-08-13
PCT/US2004/026447 WO2005016296A1 (fr) 2003-08-13 2004-08-13 Composition emulsionnee contenant de la dapsone

Publications (2)

Publication Number Publication Date
CA2535401A1 CA2535401A1 (fr) 2005-02-24
CA2535401C true CA2535401C (fr) 2011-07-26

Family

ID=34193253

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2535401A Active CA2535401C (fr) 2003-08-13 2004-08-13 Composition emulsionnee contenant de la dapsone

Country Status (6)

Country Link
EP (1) EP1675563A4 (fr)
JP (1) JP2007533606A (fr)
AU (1) AU2004264964A1 (fr)
CA (1) CA2535401C (fr)
MX (1) MXPA06001713A (fr)
WO (1) WO2005016296A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008351422A1 (en) * 2008-02-27 2009-09-03 Allergan, Inc. Dapsone to treat rosascea
CN105246457B (zh) * 2012-11-20 2019-06-07 阿勒根公司 局部氨苯砜和氨苯砜/阿达帕林组合物及其使用方法
AU2019281888B2 (en) * 2018-06-04 2024-05-02 Arcutis Biotherapeutics Inc Method and formulation for improving roflumilast skin penetration lag time

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5721242A (en) * 1993-06-17 1998-02-24 Hoffmann-La Roche Inc. Antibiotic combination
US5863560A (en) * 1996-09-11 1999-01-26 Virotex Corporation Compositions and methods for topical application of therapeutic agents
US20030157036A1 (en) * 2002-02-20 2003-08-21 Osborne David W. Topical dapsone for the treatment of acne
FR2753626B1 (fr) * 1996-09-20 1998-11-06 Centre International De Rech Dermatologiques Galderma Cird Galderma Nouvelles compositions topiques sous forme d'emulsion fluide h/e a forte teneur en glycol pro-penetrant
US6372234B1 (en) * 1997-05-27 2002-04-16 Sembiosys Genetics Inc. Products for topical applications comprising oil bodies
US6056955A (en) * 1999-09-14 2000-05-02 Fischetti; Vincent Topical treatment of streptococcal infections

Also Published As

Publication number Publication date
WO2005016296A1 (fr) 2005-02-24
JP2007533606A (ja) 2007-11-22
EP1675563A1 (fr) 2006-07-05
EP1675563A4 (fr) 2009-07-15
MXPA06001713A (es) 2007-01-26
AU2004264964A1 (en) 2005-02-24
CA2535401A1 (fr) 2005-02-24

Similar Documents

Publication Publication Date Title
US20060204526A1 (en) Emulsive composition containing Dapsone
AU647922B2 (en) Improvements in or relating to organic compounds
JP3863111B2 (ja) 半透明のナノエマルジョン、その製造方法及び、化粧品、皮膚科、及び／または眼科におけるその使用
DE60105362T2 (de) Wässrige kosmetische gele
US20090053146A1 (en) Metronidazole-based dermatological foams and emulsions for the preparation thereof
US6121314A (en) Pharmaceutical composition
WO2009129627A1 (fr) Nouvelles compositions de resvératrol
US5653989A (en) Water-in oil lotion containing corticosteroid
US20100151054A1 (en) Emulsion lotion
US10561627B2 (en) Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films
CN101048136B (zh) 微乳化和亚微米乳化方法和组合物
US20100004338A1 (en) Topical gel composition comprising azelaic acid
US20090221625A1 (en) Cosmeceutical composition
CA2535401C (fr) Composition emulsionnee contenant de la dapsone
US20010029266A1 (en) Composition containing a pentacyclic triterpenic acid, method
JP5141017B2 (ja) Ｏ／ｗエマルション組成物
US20170348261A1 (en) Medical dermatological preparation for external use
US20220331238A1 (en) Oil-in-water emulsion of mometasone
US20080075745A1 (en) Topical pharmaceutical compositions containing ciclopirox or a pharmaceutically acceptable salt thereof
JP5061519B2 (ja) 抗真菌剤含有ｏ／ｗエマルション組成物
US11007161B1 (en) Ibuprofen nanoparticle carriers encapsulated with hermatic surfactant films
JPH06239740A (ja) ミコフェノール酸含有外用治療薬
JP2023006915A (ja) 半透明乃至透明の皮膚外用剤
JP5061518B2 (ja) アモロルフィン含有ｏ／ｗエマルション組成物
JP2023006123A (ja) 水中油型乳化組成物

Legal Events

Date Code Title Description
EEER Examination request