CA2534327A1 - Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints - Google Patents
Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints Download PDFInfo
- Publication number
- CA2534327A1 CA2534327A1 CA002534327A CA2534327A CA2534327A1 CA 2534327 A1 CA2534327 A1 CA 2534327A1 CA 002534327 A CA002534327 A CA 002534327A CA 2534327 A CA2534327 A CA 2534327A CA 2534327 A1 CA2534327 A1 CA 2534327A1
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- Prior art keywords
- inhibitor
- joint
- tnf
- high specificity
- antagonist
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
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Landscapes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/630,227 US8361467B2 (en) | 2003-07-30 | 2003-07-30 | Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints |
| US10/630,227 | 2003-07-30 | ||
| PCT/US2004/024725 WO2005011689A2 (en) | 2003-07-30 | 2004-07-30 | Treatment of inflamed joints |
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| CA2534327A1 true CA2534327A1 (en) | 2005-02-10 |
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| CA002534327A Abandoned CA2534327A1 (en) | 2003-07-30 | 2004-07-30 | Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints |
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| US (1) | US8361467B2 (https=) |
| EP (1) | EP1675589A2 (https=) |
| JP (1) | JP2007500723A (https=) |
| AU (1) | AU2004260683A1 (https=) |
| CA (1) | CA2534327A1 (https=) |
| WO (1) | WO2005011689A2 (https=) |
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| US20060002935A1 (en) * | 2002-06-28 | 2006-01-05 | Domantis Limited | Tumor Necrosis Factor Receptor 1 antagonists and methods of use therefor |
| US9028822B2 (en) | 2002-06-28 | 2015-05-12 | Domantis Limited | Antagonists against TNFR1 and methods of use therefor |
| US20080008713A1 (en) * | 2002-06-28 | 2008-01-10 | Domantis Limited | Single domain antibodies against tnfr1 and methods of use therefor |
| US7553827B2 (en) * | 2003-08-13 | 2009-06-30 | Depuy Spine, Inc. | Transdiscal administration of cycline compounds |
| US7429378B2 (en) * | 2003-05-13 | 2008-09-30 | Depuy Spine, Inc. | Transdiscal administration of high affinity anti-MMP inhibitors |
| US8273347B2 (en) | 2003-05-13 | 2012-09-25 | Depuy Spine, Inc. | Autologous treatment of degenerated disc with cells |
| US20040229878A1 (en) * | 2003-05-13 | 2004-11-18 | Depuy Spine, Inc. | Transdiscal administration of specific inhibitors of P38 kinase |
| US7344716B2 (en) * | 2003-05-13 | 2008-03-18 | Depuy Spine, Inc. | Transdiscal administration of specific inhibitors of pro-inflammatory cytokines |
| US8361467B2 (en) | 2003-07-30 | 2013-01-29 | Depuy Spine, Inc. | Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints |
| US8895540B2 (en) | 2003-11-26 | 2014-11-25 | DePuy Synthes Products, LLC | Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor |
| EP1778134A1 (en) * | 2004-07-27 | 2007-05-02 | Synthes USA | Supplementation or replacement of a nucleus pulposus, of an intervertebral disc |
| US20060241758A1 (en) * | 2005-04-20 | 2006-10-26 | Sdgi Holdings, Inc. | Facet spacers |
| EP3725299A1 (en) * | 2005-06-24 | 2020-10-21 | Duke University | A direct drug delivery system based on thermally responsive biopolymers |
| JP2009508970A (ja) | 2005-09-21 | 2009-03-05 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 疼痛の局所造影および治療のためのシステム、組成物並びに方法 |
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| WO2005011689A2 (en) | 2005-02-10 |
| US8361467B2 (en) | 2013-01-29 |
| AU2004260683A1 (en) | 2005-02-10 |
| WO2005011689A3 (en) | 2005-07-14 |
| JP2007500723A (ja) | 2007-01-18 |
| US20050025765A1 (en) | 2005-02-03 |
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