CA2527429A1 - Pharmaceutical compositions and methods relating to inhibiting fibrous adhesions using various agents - Google Patents

Pharmaceutical compositions and methods relating to inhibiting fibrous adhesions using various agents Download PDF

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Publication number
CA2527429A1
CA2527429A1 CA002527429A CA2527429A CA2527429A1 CA 2527429 A1 CA2527429 A1 CA 2527429A1 CA 002527429 A CA002527429 A CA 002527429A CA 2527429 A CA2527429 A CA 2527429A CA 2527429 A1 CA2527429 A1 CA 2527429A1
Authority
CA
Canada
Prior art keywords
fibrous adhesion
agent
fibrous
inhibit
adhesion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002527429A
Other languages
English (en)
French (fr)
Inventor
Johanne Cashman
Christopher Springate
Bruce Hay
Charles Winternitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ARC PHARMACEUTICALS Inc
Original Assignee
Arc Pharmaceuticals, Inc.
Johanne Cashman
Christopher Springate
Bruce Hay
Charles Winternitz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arc Pharmaceuticals, Inc., Johanne Cashman, Christopher Springate, Bruce Hay, Charles Winternitz filed Critical Arc Pharmaceuticals, Inc.
Publication of CA2527429A1 publication Critical patent/CA2527429A1/en
Abandoned legal-status Critical Current

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • A61K31/716—Glucans
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
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  • Biochemistry (AREA)
  • Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
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CA002527429A 2003-05-30 2004-05-28 Pharmaceutical compositions and methods relating to inhibiting fibrous adhesions using various agents Abandoned CA2527429A1 (en)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US47490703P 2003-05-30 2003-05-30
US60/474,907 2003-05-30
US47765403P 2003-06-10 2003-06-10
US60/477,654 2003-06-10
US50525703P 2003-09-22 2003-09-22
US50525803P 2003-09-22 2003-09-22
US60/505,257 2003-09-22
US60/505,258 2003-09-22
US52080403P 2003-11-17 2003-11-17
US52057403P 2003-11-17 2003-11-17
US52080803P 2003-11-17 2003-11-17
US60/520,574 2003-11-17
US60/520,808 2003-11-17
US60/520,804 2003-11-17
US52913603P 2003-12-11 2003-12-11
US60/529,136 2003-12-11
US53366903P 2003-12-31 2003-12-31
US60/533,669 2003-12-31
PCT/CA2004/000800 WO2004105737A2 (en) 2003-05-30 2004-05-28 Pharmaceutical compositions and methods relating to inhibiting fibrous adhesions using various agents

Publications (1)

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CA2527429A1 true CA2527429A1 (en) 2004-12-09

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CA002527429A Abandoned CA2527429A1 (en) 2003-05-30 2004-05-28 Pharmaceutical compositions and methods relating to inhibiting fibrous adhesions using various agents

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BRPI0418384A (pt) 2007-06-26
EP1631265A2 (en) 2006-03-08
TW200509949A (en) 2005-03-16
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