CA2525452A1 - Novel 14 and 15 membered-ring compounds - Google Patents

Novel 14 and 15 membered-ring compounds Download PDF

Info

Publication number
CA2525452A1
CA2525452A1 CA002525452A CA2525452A CA2525452A1 CA 2525452 A1 CA2525452 A1 CA 2525452A1 CA 002525452 A CA002525452 A CA 002525452A CA 2525452 A CA2525452 A CA 2525452A CA 2525452 A1 CA2525452 A1 CA 2525452A1
Authority
CA
Canada
Prior art keywords
hydrogen
optionally substituted
6alkyl
ethyl
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002525452A
Other languages
English (en)
French (fr)
Inventor
Sulejman Alihodzic
Andrew Keith Forrest
Richard Lewis Jarvest
Gorjana Lazarevski
Drazen Pavlovic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Fidelta doo
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2525452A1 publication Critical patent/CA2525452A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA002525452A 2003-05-13 2004-05-11 Novel 14 and 15 membered-ring compounds Abandoned CA2525452A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0310986.5 2003-05-13
GBGB0310986.5A GB0310986D0 (en) 2003-05-13 2003-05-13 Novel compounds
PCT/EP2004/005082 WO2004101586A1 (en) 2003-05-13 2004-05-11 Novel 14 and 15 membered-ring compounds

Publications (1)

Publication Number Publication Date
CA2525452A1 true CA2525452A1 (en) 2004-11-25

Family

ID=9957984

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002525452A Abandoned CA2525452A1 (en) 2003-05-13 2004-05-11 Novel 14 and 15 membered-ring compounds

Country Status (22)

Country Link
US (1) US7569550B2 (enExample)
EP (1) EP1628988B1 (enExample)
JP (1) JP2007502313A (enExample)
KR (1) KR20060026407A (enExample)
CN (1) CN1849328A (enExample)
AR (1) AR044309A1 (enExample)
AT (1) ATE341560T1 (enExample)
AU (1) AU2004238528A1 (enExample)
BR (1) BRPI0410246A (enExample)
CA (1) CA2525452A1 (enExample)
CL (1) CL2004001010A1 (enExample)
DE (1) DE602004002696T2 (enExample)
DK (1) DK1628988T3 (enExample)
ES (1) ES2273255T3 (enExample)
GB (1) GB0310986D0 (enExample)
HR (1) HRP20060448T3 (enExample)
MX (1) MXPA05012163A (enExample)
PL (1) PL1628988T3 (enExample)
PT (1) PT1628988E (enExample)
RU (1) RU2005134908A (enExample)
WO (1) WO2004101586A1 (enExample)
ZA (1) ZA200509079B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0424958D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
WO2007054295A1 (en) * 2005-11-09 2007-05-18 Glaxo Group Limited New 4*-substituted erythromycin derivative
GB0424961D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
DE602006015919D1 (de) * 2005-01-13 2010-09-16 Glaxosmithkline Zagreb Makrolide mit entzündungshemmender wirkung
JP2008540503A (ja) 2005-05-10 2008-11-20 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 細菌感染症の処置に有用なエーテル結合マクロライド
WO2007054296A1 (en) * 2005-11-09 2007-05-18 Glaxo Group Limited Macrolones
JP5437394B2 (ja) 2009-01-30 2014-03-12 グラクソ グループ リミテッド 抗炎症性マクロライド
CN111574575B (zh) * 2020-04-29 2022-05-17 北京理工大学 一种含有大环内酯基的喹喏酮衍生物、制备方法及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL93936A (en) * 1989-03-28 1994-06-24 Abbott Lab History of 9-dioxo-21,9-epoxy - erythromycin, method of preparation History of 11-oxo and 11-hydroxy, and pharmaceutical preparations containing them
WO1996034007A1 (es) * 1995-04-27 1996-10-31 Laboratorios Aranda, S.A. De C.V. Derivados de quinolonilcarboxieritromicina y composiciones farmaceuticas que los contienen
DE69723848T2 (de) * 1996-05-07 2004-07-01 Abbott Laboratories, Abbott Park 3-descladinose-2,3-anhydroerythromycin-derivate
GB0025688D0 (en) * 2000-10-19 2000-12-06 Glaxo Group Ltd Macrolides
JP4311203B2 (ja) * 2001-08-08 2009-08-12 大正製薬株式会社 11a−アザライド化合物及びその製造方法
GB0127349D0 (en) 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides

Also Published As

Publication number Publication date
PL1628988T3 (pl) 2007-03-30
GB0310986D0 (en) 2003-06-18
WO2004101586A1 (en) 2004-11-25
US7569550B2 (en) 2009-08-04
RU2005134908A (ru) 2006-06-27
DK1628988T3 (da) 2007-02-05
AR044309A1 (es) 2005-09-07
ZA200509079B (en) 2007-02-28
JP2007502313A (ja) 2007-02-08
MXPA05012163A (es) 2006-05-19
AU2004238528A1 (en) 2004-11-25
CL2004001010A1 (es) 2005-03-18
DE602004002696D1 (de) 2006-11-16
KR20060026407A (ko) 2006-03-23
EP1628988A1 (en) 2006-03-01
ATE341560T1 (de) 2006-10-15
CN1849328A (zh) 2006-10-18
US20070185117A1 (en) 2007-08-09
BRPI0410246A (pt) 2006-05-16
EP1628988B1 (en) 2006-10-04
PT1628988E (pt) 2007-01-31
HRP20060448T3 (hr) 2007-03-31
ES2273255T3 (es) 2007-05-01
DE602004002696T2 (de) 2007-08-16

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Legal Events

Date Code Title Description
FZDE Discontinued