CA2520671C - Compositions and methods involving respiratory syncytial virus subgroup b strain 9320 - Google Patents
Compositions and methods involving respiratory syncytial virus subgroup b strain 9320 Download PDFInfo
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
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- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (5)
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| US45833103P | 2003-03-28 | 2003-03-28 | |
| US60/458,331 | 2003-03-28 | ||
| US50832003P | 2003-10-03 | 2003-10-03 | |
| US60/508,320 | 2003-10-03 | ||
| PCT/US2004/009438 WO2004087062A2 (en) | 2003-03-28 | 2004-03-26 | Compositions and methods involving respiratory syncytial virus subgroup b strain 9320 |
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| CA2520671A1 CA2520671A1 (en) | 2004-10-14 |
| CA2520671C true CA2520671C (en) | 2014-03-18 |
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| CA2520671A Expired - Fee Related CA2520671C (en) | 2003-03-28 | 2004-03-26 | Compositions and methods involving respiratory syncytial virus subgroup b strain 9320 |
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| US (3) | US7572904B2 (enExample) |
| EP (1) | EP1613345B1 (enExample) |
| JP (1) | JP4783726B2 (enExample) |
| AT (1) | ATE469170T1 (enExample) |
| AU (1) | AU2004226369A1 (enExample) |
| CA (1) | CA2520671C (enExample) |
| DE (1) | DE602004027362D1 (enExample) |
| WO (1) | WO2004087062A2 (enExample) |
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| JP2007531491A (ja) * | 2002-09-27 | 2007-11-08 | メディミューン・ヴァクシンズ・インコーポレーテッド | 呼吸器合胞体ウイルスにおける機能的突然変異 |
| AU2004226369A1 (en) * | 2003-03-28 | 2004-10-14 | Medimmune, Llc | Compositions and methods involving respiratory syncytial virus subgroup B strain 9320 |
| FR2885139B1 (fr) | 2005-04-29 | 2010-12-24 | Agronomique Inst Nat Rech | Preparation de complexes solubles proteine n-proteine p tronquee ou de proteine n soluble d'un virus de la famille des paramyxoviridae et leurs utilisations vaccinales |
| WO2007093050A1 (en) * | 2006-02-13 | 2007-08-23 | Olga Ornatsky | Gene expression assays conducted by elemental analysis |
| AU2007222798A1 (en) * | 2006-03-06 | 2007-09-13 | Symphogen A/S | Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections |
| FR2899902B1 (fr) * | 2006-04-18 | 2012-01-27 | Agronomique Inst Nat Rech | Proteines de fusion proteine n d'un virus de la famille des paramyxoviridae-proteine d'interet et leurs utilisations pour la vaccination et la vectorisation intra-cellulaire. |
| CN101679513A (zh) * | 2007-03-06 | 2010-03-24 | 西福根有限公司 | 用于治疗呼吸道合胞病毒感染的重组抗体 |
| EP2069485A4 (en) * | 2007-07-13 | 2011-05-25 | Medimmune Llc | PREPARATION OF NEGATIVE STRAND RNA VIRUSES BY ELECTROPORATION |
| US8354230B2 (en) | 2007-12-21 | 2013-01-15 | Quest Diagnostics Investments Inc. | Multiplex detection assay for influenza and RSV viruses |
| AU2009311287C1 (en) * | 2008-11-05 | 2015-02-19 | Merck Sharp & Dohme Corp. | Live, attentuated respiratory syncytial virus |
| GB201019240D0 (en) | 2010-11-15 | 2010-12-29 | Vib Vzw | Respiratory syncytical virus vaccine |
| US10227569B2 (en) * | 2011-04-12 | 2019-03-12 | Emory University | Respiratory syncytial virus expression vectors |
| ES2854673T3 (es) | 2013-03-14 | 2021-09-22 | Univ Emory | VSR recombinante con mutaciones silenciosas, vacunas y métodos relacionados con ello |
| WO2017075125A1 (en) | 2015-10-29 | 2017-05-04 | Emory University | Chimeric RSV, Immunogenic Compositions, and Methods of Use |
| US12102671B2 (en) | 2015-11-04 | 2024-10-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Method of vaccination with an attenuated RSV vaccine formulation |
| AU2023349013A1 (en) * | 2022-09-29 | 2025-04-17 | Beijing Benewill Technology Development Co., Ltd. | Respiratory syncytial virus recombinant fusion protein with prefusion conformation, and preparation method therefor and use thereof |
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| US4800078A (en) | 1987-05-28 | 1989-01-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Immunotherapeutic method of treating respiratory disease by intranasal administration of Igb |
| US5840520A (en) * | 1989-08-28 | 1998-11-24 | Aviron | Recombinant negative strand RNA virus expression systems |
| GB9200117D0 (en) | 1992-01-06 | 1992-02-26 | Connaught Lab | Production of recombinant chimeric proteins for vaccine use |
| IL105456A (en) | 1992-04-21 | 1996-12-05 | American Home Prod | Vaccines of attenuated respiratory syncytial virus |
| US20030054505A1 (en) * | 1997-09-26 | 2003-03-20 | Hong Jin | Recombinant rsv expression systems and vaccines |
| US6713066B1 (en) | 1996-07-15 | 2004-03-30 | The United States Of America As Represented By The Department Of Health And Human Services | Production of attenuated respiratory syncytial virus vaccines involving modification of M2 ORF2 |
| EP0932684A2 (en) * | 1996-09-27 | 1999-08-04 | American Cyanamid Company | 3' genomic promoter region and polymerase gene mutations responsible for attenuation in viruses of the order designated mononegavirales |
| US6017694A (en) * | 1997-12-19 | 2000-01-25 | American Cyanamid Company | Methods of screening for modulators of respiratory syncytial virus matrix protein interaction |
| JP2002507408A (ja) * | 1998-03-26 | 2002-03-12 | アメリカン・サイアナミド・カンパニー | 麻疹ウイルスもしくはヒト呼吸合胞体ウイルスサブグループｂの弱毒化の原因である突然変異 |
| CA2430115C (en) | 2000-11-28 | 2013-02-26 | Aviron, Inc. | Recombinant rsv virus expression systems and vaccines |
| DK1351981T3 (da) * | 2001-01-19 | 2012-11-26 | Vironovative Bv | Et virus, der forårsager luftvejssygdom hos modtagelige pattedyr |
| JP2007531491A (ja) | 2002-09-27 | 2007-11-08 | メディミューン・ヴァクシンズ・インコーポレーテッド | 呼吸器合胞体ウイルスにおける機能的突然変異 |
| AU2004226369A1 (en) * | 2003-03-28 | 2004-10-14 | Medimmune, Llc | Compositions and methods involving respiratory syncytial virus subgroup B strain 9320 |
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2004
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- 2004-03-26 DE DE602004027362T patent/DE602004027362D1/de not_active Expired - Lifetime
- 2004-03-26 WO PCT/US2004/009438 patent/WO2004087062A2/en not_active Ceased
- 2004-03-26 EP EP04749465A patent/EP1613345B1/en not_active Expired - Lifetime
- 2004-03-26 AT AT04749465T patent/ATE469170T1/de not_active IP Right Cessation
- 2004-03-26 US US10/811,508 patent/US7572904B2/en not_active Expired - Lifetime
- 2004-03-26 CA CA2520671A patent/CA2520671C/en not_active Expired - Fee Related
- 2004-03-26 JP JP2006509391A patent/JP4783726B2/ja not_active Expired - Fee Related
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2009
- 2009-07-23 US US12/508,075 patent/US8163530B2/en not_active Expired - Lifetime
-
2012
- 2012-04-17 US US13/449,087 patent/US20120263744A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1613345B1 (en) | 2010-05-26 |
| AU2004226369A1 (en) | 2004-10-14 |
| WO2004087062A3 (en) | 2005-03-31 |
| JP2006524053A (ja) | 2006-10-26 |
| US20040224309A1 (en) | 2004-11-11 |
| EP1613345A2 (en) | 2006-01-11 |
| WO2004087062A2 (en) | 2004-10-14 |
| DE602004027362D1 (de) | 2010-07-08 |
| CA2520671A1 (en) | 2004-10-14 |
| US20120263744A1 (en) | 2012-10-18 |
| EP1613345A4 (en) | 2007-01-10 |
| US20090285853A1 (en) | 2009-11-19 |
| ATE469170T1 (de) | 2010-06-15 |
| JP4783726B2 (ja) | 2011-09-28 |
| US7572904B2 (en) | 2009-08-11 |
| US8163530B2 (en) | 2012-04-24 |
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