CA2514449A1 - Restauration des fonctions des recepteurs mutants de l'hormone de liberation de la gonadotrophine - Google Patents
Restauration des fonctions des recepteurs mutants de l'hormone de liberation de la gonadotrophine Download PDFInfo
- Publication number
- CA2514449A1 CA2514449A1 CA002514449A CA2514449A CA2514449A1 CA 2514449 A1 CA2514449 A1 CA 2514449A1 CA 002514449 A CA002514449 A CA 002514449A CA 2514449 A CA2514449 A CA 2514449A CA 2514449 A1 CA2514449 A1 CA 2514449A1
- Authority
- CA
- Canada
- Prior art keywords
- gnrhr
- mutant
- macrolide
- indole
- quinolone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- CYRMSUTZVYGINF-UHFFFAOYSA-N trichlorofluoromethane Chemical compound FC(Cl)(Cl)Cl CYRMSUTZVYGINF-UHFFFAOYSA-N 0.000 description 1
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- 239000001226 triphosphate Substances 0.000 description 1
- XPFJYKARVSSRHE-UHFFFAOYSA-K trisodium;2-hydroxypropane-1,2,3-tricarboxylate;2-hydroxypropane-1,2,3-tricarboxylic acid Chemical compound [Na+].[Na+].[Na+].OC(=O)CC(O)(C(O)=O)CC(O)=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O XPFJYKARVSSRHE-UHFFFAOYSA-K 0.000 description 1
- LEAHFJQFYSDGGP-UHFFFAOYSA-K trisodium;dihydrogen phosphate;hydrogen phosphate Chemical compound [Na+].[Na+].[Na+].OP(O)([O-])=O.OP([O-])([O-])=O LEAHFJQFYSDGGP-UHFFFAOYSA-K 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44369103P | 2003-01-29 | 2003-01-29 | |
| US60/443,691 | 2003-01-29 | ||
| PCT/US2004/002290 WO2004069859A2 (fr) | 2003-01-29 | 2004-01-27 | Restauration des fonctions des recepteurs mutants de l'hormone de liberation de la gonadotrophine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2514449A1 true CA2514449A1 (fr) | 2004-08-19 |
Family
ID=32850796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002514449A Abandoned CA2514449A1 (fr) | 2003-01-29 | 2004-01-27 | Restauration des fonctions des recepteurs mutants de l'hormone de liberation de la gonadotrophine |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1599494A4 (fr) |
| AU (1) | AU2004208990B2 (fr) |
| CA (1) | CA2514449A1 (fr) |
| WO (1) | WO2004069859A2 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070021433A1 (en) | 2005-06-03 | 2007-01-25 | Jian-Qiang Fan | Pharmacological chaperones for treating obesity |
| AU2010254092B2 (en) * | 2009-05-26 | 2015-11-12 | Amicus Therapeutics, Inc. | Utilization of pharmacological chaperones to improve manufacturing and purification of biologics |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003038036A2 (fr) * | 2001-10-09 | 2003-05-08 | Oregon Health & Science University | Sauvetage de mutants du recepteur de la gonadoliberine |
-
2004
- 2004-01-27 CA CA002514449A patent/CA2514449A1/fr not_active Abandoned
- 2004-01-27 AU AU2004208990A patent/AU2004208990B2/en not_active Ceased
- 2004-01-27 WO PCT/US2004/002290 patent/WO2004069859A2/fr active Application Filing
- 2004-01-27 EP EP04705679A patent/EP1599494A4/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004069859A2 (fr) | 2004-08-19 |
| EP1599494A2 (fr) | 2005-11-30 |
| EP1599494A4 (fr) | 2010-01-06 |
| WO2004069859A3 (fr) | 2009-04-02 |
| AU2004208990B2 (en) | 2010-11-11 |
| AU2004208990A1 (en) | 2004-08-19 |
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