CA2508264A1 - Methods of treatment of ulcerative colitis with anti-cd3 antibodies - Google Patents
Methods of treatment of ulcerative colitis with anti-cd3 antibodies Download PDFInfo
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- CA2508264A1 CA2508264A1 CA002508264A CA2508264A CA2508264A1 CA 2508264 A1 CA2508264 A1 CA 2508264A1 CA 002508264 A CA002508264 A CA 002508264A CA 2508264 A CA2508264 A CA 2508264A CA 2508264 A1 CA2508264 A1 CA 2508264A1
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
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- Epidemiology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| US43164902P | 2002-12-05 | 2002-12-05 | |
| US60/431,649 | 2002-12-05 | ||
| US45018303P | 2003-02-25 | 2003-02-25 | |
| US60/450,183 | 2003-02-25 | ||
| PCT/US2003/038809 WO2004052397A1 (en) | 2002-12-05 | 2003-12-05 | Methods of treatment of ulcerative colitis with anti-cd3 antibodies |
Publications (1)
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|---|---|
| CA2508264A1 true CA2508264A1 (en) | 2004-06-24 |
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| CA002508264A Abandoned CA2508264A1 (en) | 2002-12-05 | 2003-12-05 | Methods of treatment of ulcerative colitis with anti-cd3 antibodies |
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| US (1) | US20040253237A1 (enExample) |
| EP (1) | EP1567192A4 (enExample) |
| JP (1) | JP2006511620A (enExample) |
| KR (1) | KR20050091713A (enExample) |
| AU (1) | AU2003298015A1 (enExample) |
| CA (1) | CA2508264A1 (enExample) |
| WO (1) | WO2004052397A1 (enExample) |
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| WO2005048935A2 (en) | 2003-11-14 | 2005-06-02 | Brigham And Women's Hospital, Inc. | Methods of modulating immunity |
| EP1753783B1 (en) | 2004-06-03 | 2014-08-06 | Novimmune SA | Anti-cd3 antibodies and methods of use thereof |
| WO2007026742A1 (ja) * | 2005-08-30 | 2007-03-08 | Ajinomoto Co., Inc. | 大腸デリバリー型炎症性大腸疾患治療薬 |
| BRPI0615745A2 (pt) * | 2005-09-12 | 2011-05-24 | Novimmune Sa | formulação de anticorpo anti-cd3 |
| AU2012201443B2 (en) * | 2006-06-06 | 2014-04-03 | Glaxo Group Limited | Administration of anti-CD3 antibodies in the treatment of autoimmune diseases |
| JP2009539841A (ja) * | 2006-06-06 | 2009-11-19 | トラークス，インコーポレイテッド | 自己免疫疾患の治療における抗ｃｄ３抗体の投与 |
| MX349057B (es) | 2010-11-30 | 2017-07-07 | Chugai Pharmaceutical Co Ltd | Agente terapeutico que induce citotoxicidad. |
| WO2017077382A1 (en) | 2015-11-06 | 2017-05-11 | Orionis Biosciences Nv | Bi-functional chimeric proteins and uses thereof |
| CN115850521A (zh) | 2016-02-05 | 2023-03-28 | 奥里尼斯生物科学私人有限公司 | 靶向性治疗剂及其用途 |
| CA3026474A1 (en) | 2016-06-20 | 2017-12-28 | Kymab Limited | Anti-pd-l1 and il-2 cytokines |
| EP3551034A1 (en) | 2016-12-07 | 2019-10-16 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| CN110573172A (zh) | 2017-02-06 | 2019-12-13 | 奥里尼斯生物科学有限公司 | 靶向的工程化干扰素及其用途 |
| EP4108183A1 (en) | 2017-03-30 | 2022-12-28 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| US12227565B2 (en) | 2018-06-20 | 2025-02-18 | Biora Therapeutics, Inc. | Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine |
| WO2020106704A2 (en) | 2018-11-19 | 2020-05-28 | Progenity, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
| CN121197633A (zh) | 2019-12-13 | 2025-12-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| CN113005088B (zh) * | 2019-12-19 | 2024-06-04 | 苏州方德门达新药开发有限公司 | 工程改造的t细胞、其制备及应用 |
| WO2023174925A1 (en) | 2022-03-14 | 2023-09-21 | Novimmune Sa | Bispecific gpc3xcd28 and gpc3xcd3 antibodies and their combination for targeted killing of gpc3 positive malignant cells |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5932214A (en) * | 1994-08-11 | 1999-08-03 | Biogen, Inc. | Treatment for inflammatory bowel disease with VLA-4 blockers |
| US5834597A (en) * | 1996-05-20 | 1998-11-10 | Protein Design Labs, Inc. | Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same |
| DE19905012A1 (de) * | 1999-02-08 | 2000-08-10 | Gsf Forschungszentrum Umwelt | Arzneimittel enthaltend Anti-CD3- und Anti-Fcgamma-R-Antikörper zur begleitenden Behandlung bei Organtransplantationen |
| PL218992B1 (pl) * | 2002-07-19 | 2015-02-27 | Abbott Biotech Ltd | Neutralizujące o wysokim powinowactwie izolowane ludzkie przeciwciało anty-TNFα, zastosowanie tego przeciwciała, kryształ zawierający ludzkie przeciwciało anty-TNFα i preparat zawierający ten kryształ |
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2003
- 2003-12-05 CA CA002508264A patent/CA2508264A1/en not_active Abandoned
- 2003-12-05 AU AU2003298015A patent/AU2003298015A1/en not_active Abandoned
- 2003-12-05 EP EP03796736A patent/EP1567192A4/en not_active Withdrawn
- 2003-12-05 WO PCT/US2003/038809 patent/WO2004052397A1/en not_active Ceased
- 2003-12-05 KR KR1020057010239A patent/KR20050091713A/ko not_active Withdrawn
- 2003-12-05 JP JP2005508486A patent/JP2006511620A/ja active Pending
- 2003-12-05 US US10/729,795 patent/US20040253237A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004052397A1 (en) | 2004-06-24 |
| US20040253237A1 (en) | 2004-12-16 |
| AU2003298015A1 (en) | 2004-06-30 |
| EP1567192A1 (en) | 2005-08-31 |
| JP2006511620A (ja) | 2006-04-06 |
| KR20050091713A (ko) | 2005-09-15 |
| EP1567192A4 (en) | 2006-02-08 |
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