AU2003298015A1 - Methods of treatment of ulcerative colitis with anti-cd3 antibodies - Google Patents
Methods of treatment of ulcerative colitis with anti-cd3 antibodies Download PDFInfo
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- C—CHEMISTRY; METALLURGY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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Applications Claiming Priority (5)
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| US43164902P | 2002-12-05 | 2002-12-05 | |
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| US45018303P | 2003-02-25 | 2003-02-25 | |
| US60/450,183 | 2003-02-25 | ||
| PCT/US2003/038809 WO2004052397A1 (en) | 2002-12-05 | 2003-12-05 | Methods of treatment of ulcerative colitis with anti-cd3 antibodies |
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| AU2003298015A1 true AU2003298015A1 (en) | 2004-06-30 |
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| EP2397189B1 (en) | 2003-11-14 | 2015-03-18 | Brigham and Women's Hospital, Inc. | Methods of modulating immunity |
| EA010350B1 (ru) | 2004-06-03 | 2008-08-29 | Новиммун С.А. | Антитела против cd3 и способы их применения |
| EP1941874A4 (en) * | 2005-08-30 | 2012-03-28 | Ajinomoto Kk | THERAPEUTIC MEANS FOR DELIVERY IN THE COLON AGAINST INFLAMMATORY ENDURANCE |
| AU2006291005A1 (en) * | 2005-09-12 | 2007-03-22 | Novimmune S.A. | Anti-CD3 antibody formulations |
| CA2653387A1 (en) * | 2006-06-06 | 2007-12-21 | Tolerrx, Inc. | Administration of anti-cd3 antibodies in the treatment of autoimmune diseases |
| AU2012201443B2 (en) * | 2006-06-06 | 2014-04-03 | Glaxo Group Limited | Administration of anti-CD3 antibodies in the treatment of autoimmune diseases |
| TWI807362B (zh) | 2010-11-30 | 2023-07-01 | 日商中外製藥股份有限公司 | 細胞傷害誘導治療劑 |
| EP3371311B1 (en) | 2015-11-06 | 2021-07-21 | Orionis Biosciences BV | Bi-functional chimeric proteins and uses thereof |
| EP3411065B1 (en) | 2016-02-05 | 2021-03-31 | Orionis Biosciences BV | Clec9a binding agents |
| JP7461741B2 (ja) | 2016-06-20 | 2024-04-04 | カイマブ・リミテッド | 抗ｐｄ－ｌ１およびｉｌ－２サイトカイン |
| WO2018106931A1 (en) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| US10906985B2 (en) | 2017-02-06 | 2021-02-02 | Orionis Biosciences, Inc. | Targeted engineered interferon and uses thereof |
| CA3054632A1 (en) | 2017-03-30 | 2018-10-04 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| US12227565B2 (en) | 2018-06-20 | 2025-02-18 | Biora Therapeutics, Inc. | Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine |
| CN116726361A (zh) | 2018-11-19 | 2023-09-12 | 比奥拉治疗股份有限公司 | 用生物治疗剂治疗疾病的方法和装置 |
| US11707610B2 (en) | 2019-12-13 | 2023-07-25 | Biora Therapeutics, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
| CN118562007A (zh) * | 2019-12-19 | 2024-08-30 | 苏州方德门达新药开发有限公司 | 工程改造的t细胞、其制备及应用 |
| EP4493592A1 (en) | 2022-03-14 | 2025-01-22 | LamKap Bio gamma AG | Bispecific gpc3xcd28 and gpc3xcd3 antibodies and their combination for targeted killing of gpc3 positive malignant cells |
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| US5932214A (en) * | 1994-08-11 | 1999-08-03 | Biogen, Inc. | Treatment for inflammatory bowel disease with VLA-4 blockers |
| US5834597A (en) * | 1996-05-20 | 1998-11-10 | Protein Design Labs, Inc. | Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same |
| DE19905012A1 (de) * | 1999-02-08 | 2000-08-10 | Gsf Forschungszentrum Umwelt | Arzneimittel enthaltend Anti-CD3- und Anti-Fcgamma-R-Antikörper zur begleitenden Behandlung bei Organtransplantationen |
| NZ555692A (en) * | 2002-07-19 | 2009-02-28 | Abbott Biotech Ltd | Treatment of TNF alpha related disorders |
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| EP1567192A1 (en) | 2005-08-31 |
| WO2004052397A1 (en) | 2004-06-24 |
| CA2508264A1 (en) | 2004-06-24 |
| KR20050091713A (ko) | 2005-09-15 |
| JP2006511620A (ja) | 2006-04-06 |
| EP1567192A4 (en) | 2006-02-08 |
| US20040253237A1 (en) | 2004-12-16 |
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