CA2506797C - Detectable labeled nucleoside analogs and methods of use thereof - Google Patents
Detectable labeled nucleoside analogs and methods of use thereof Download PDFInfo
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- CA2506797C CA2506797C CA002506797A CA2506797A CA2506797C CA 2506797 C CA2506797 C CA 2506797C CA 002506797 A CA002506797 A CA 002506797A CA 2506797 A CA2506797 A CA 2506797A CA 2506797 C CA2506797 C CA 2506797C
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/067—Pyrimidine radicals with ribosyl as the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
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|---|---|---|---|
| US42848402P | 2002-11-22 | 2002-11-22 | |
| US60/428,484 | 2002-11-22 | ||
| PCT/EP2003/013014 WO2004048397A2 (en) | 2002-11-22 | 2003-11-20 | Detectable labeled nucleoside analogs and methods of use thereof |
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|---|---|
| CA2506797A1 CA2506797A1 (en) | 2004-06-10 |
| CA2506797C true CA2506797C (en) | 2009-02-10 |
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|---|---|---|---|
| CA002506797A Expired - Lifetime CA2506797C (en) | 2002-11-22 | 2003-11-20 | Detectable labeled nucleoside analogs and methods of use thereof |
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| EP1725572B1 (de) * | 2003-11-05 | 2017-05-31 | AGCT GmbH | Makromolekulare nukleotidverbindungen und methoden zu deren anwendung |
| US20050147965A1 (en) * | 2003-12-31 | 2005-07-07 | Zhong Zhandong D. | Compositions and methods for detecting reverse transcriptase in a sample |
| US7745125B2 (en) | 2004-06-28 | 2010-06-29 | Roche Molecular Systems, Inc. | 2′-terminator related pyrophosphorolysis activated polymerization |
| WO2006048262A2 (en) * | 2004-11-04 | 2006-05-11 | Roche Diagnostics Gmbh | Classification of acute myeloid leukemia |
| US9035035B2 (en) * | 2004-11-05 | 2015-05-19 | Genovoxx Gmbh | Macromolecular nucleotide compounds and methods for using the same |
| EP1908848B1 (en) * | 2005-05-17 | 2013-04-17 | Sumitomo Bakelite Company, Ltd. | Method for detection of gene |
| US7919242B2 (en) | 2005-06-30 | 2011-04-05 | Roche Molecular Systems, Inc. | Light emission modifiers and their uses in nucleic acid detection, amplification and analysis |
| GB0517097D0 (en) † | 2005-08-19 | 2005-09-28 | Solexa Ltd | Modified nucleosides and nucleotides and uses thereof |
| WO2009100382A1 (en) * | 2008-02-07 | 2009-08-13 | Pacific Biosciences Of California, Inc. | Cis reactive oxygen quenchers integrated into linkers |
| WO2009105258A1 (en) | 2008-02-22 | 2009-08-27 | Nektar Therapeutics Al, Corporation | Oligomer conjugates of heteropentacyclic nucleosides |
| JP5850746B2 (ja) * | 2008-11-17 | 2016-02-03 | ヘッドウェイ テクノロジーズ, インク.Headway Technologies, Inc. | 連結分子を用いた標的分子の粒子ベースの検出における方法および組成物 |
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-
2003
- 2003-11-20 WO PCT/EP2003/013014 patent/WO2004048397A2/en active Application Filing
- 2003-11-20 EP EP03785650.7A patent/EP1565480B1/en not_active Expired - Lifetime
- 2003-11-20 AU AU2003294716A patent/AU2003294716A1/en not_active Abandoned
- 2003-11-20 CA CA002506797A patent/CA2506797C/en not_active Expired - Lifetime
- 2003-11-20 JP JP2004554406A patent/JP4898119B2/ja not_active Expired - Lifetime
- 2003-11-21 US US10/719,257 patent/US7220847B2/en active Active
-
2007
- 2007-04-30 US US11/742,123 patent/US7501504B2/en not_active Expired - Lifetime
- 2007-04-30 US US11/742,070 patent/US7456266B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US7456266B2 (en) | 2008-11-25 |
| JP4898119B2 (ja) | 2012-03-14 |
| US20040171040A1 (en) | 2004-09-02 |
| AU2003294716A1 (en) | 2004-06-18 |
| CA2506797A1 (en) | 2004-06-10 |
| US7501504B2 (en) | 2009-03-10 |
| JP2006510623A (ja) | 2006-03-30 |
| WO2004048397A2 (en) | 2004-06-10 |
| WO2004048397A3 (en) | 2004-07-01 |
| EP1565480B1 (en) | 2018-08-22 |
| US20070208169A1 (en) | 2007-09-06 |
| EP1565480A2 (en) | 2005-08-24 |
| US7220847B2 (en) | 2007-05-22 |
| AU2003294716A8 (en) | 2004-06-18 |
| US20070202576A1 (en) | 2007-08-30 |
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