CA2504829C - Diagnostic assay for measuring a cell mediated immune response - Google Patents

Diagnostic assay for measuring a cell mediated immune response Download PDF

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Publication number
CA2504829C
CA2504829C CA2504829A CA2504829A CA2504829C CA 2504829 C CA2504829 C CA 2504829C CA 2504829 A CA2504829 A CA 2504829A CA 2504829 A CA2504829 A CA 2504829A CA 2504829 C CA2504829 C CA 2504829C
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CA
Canada
Prior art keywords
antigen
immune
cells
subject
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2504829A
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English (en)
French (fr)
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CA2504829A1 (en
Inventor
James Stuart Rothel
Steven Paul Wild
Angela Cosgriff
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Cellestis Ltd
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Cellestis Ltd
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Application filed by Cellestis Ltd filed Critical Cellestis Ltd
Publication of CA2504829A1 publication Critical patent/CA2504829A1/en
Application granted granted Critical
Publication of CA2504829C publication Critical patent/CA2504829C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047Cells of the immune system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Physiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Holo Graphy (AREA)
  • Inspection Of Paper Currency And Valuable Securities (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2504829A 2002-11-08 2003-11-06 Diagnostic assay for measuring a cell mediated immune response Expired - Lifetime CA2504829C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2002952548 2002-11-08
AU2002952548A AU2002952548A0 (en) 2002-11-08 2002-11-08 Diagnostic assay
PCT/AU2003/001464 WO2004042396A1 (en) 2002-11-08 2003-11-06 Diagnostic assay for measuring a cell mediated immune response

Publications (2)

Publication Number Publication Date
CA2504829A1 CA2504829A1 (en) 2004-05-21
CA2504829C true CA2504829C (en) 2013-01-22

Family

ID=28795938

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2504829A Expired - Lifetime CA2504829C (en) 2002-11-08 2003-11-06 Diagnostic assay for measuring a cell mediated immune response

Country Status (8)

Country Link
US (1) US7608392B2 (https=)
EP (1) EP1561106B1 (https=)
JP (1) JP4502814B2 (https=)
AT (1) ATE429640T1 (https=)
AU (1) AU2002952548A0 (https=)
CA (1) CA2504829C (https=)
DE (1) DE60327354D1 (https=)
WO (1) WO2004042396A1 (https=)

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JP2006189338A (ja) * 2005-01-06 2006-07-20 Sekisui Chem Co Ltd 炎症性腸疾患の治療前効果予測方法並びに治療効果の判定方法
GB0616238D0 (en) * 2006-08-15 2006-09-27 Inst Animal Health Ltd Diagnostic Test
DE602007013620D1 (de) * 2006-09-05 2011-05-12 Hvidovre Hospital Auf IP-10 basierende immunologische Überwachung
WO2008147426A2 (en) * 2006-10-04 2008-12-04 The Brigham And Women's Hospital, Inc. Methods and compositions for immunomodulation
CN101711360A (zh) * 2007-03-16 2010-05-19 赛乐思迪斯有限公司 细胞介导的免疫应答检验及其试剂盒
WO2008128069A1 (en) * 2007-04-11 2008-10-23 Roger Deutsch Methods for diagnosing biological samples containing stem cells
US20090062237A1 (en) * 2007-06-15 2009-03-05 Mayo Foundation For Medical Education And Research Evaluating immune competence
US20100221755A1 (en) * 2007-06-15 2010-09-02 University Of Rochester Use of antibody secreting cell elispot to assess antibody responses following antigen exposure
CN102105786B (zh) * 2008-07-25 2014-10-29 赛乐思迪斯有限公司 诊断方法
HUE027237T2 (en) 2008-11-30 2016-10-28 Immusant Inc Compositions and methods for treatment of celiac disease
CN102573883A (zh) 2009-06-12 2012-07-11 疫苗技术公司 用于促进细胞-介导的免疫应答的方法和组合物
WO2010144794A1 (en) 2009-06-12 2010-12-16 Vaccine Technologies, Incorporated Baculovirus-expressed fusion polypeptide vaccines with enhanced immunogenicity and uses thereof
AU2010336016B2 (en) * 2009-12-23 2017-07-27 Qiagen Sciences Llc An assay for measuring cell-mediated immunoresponsiveness
US8771967B2 (en) 2010-11-16 2014-07-08 The Board Of Trustees Of The Leland Stanford Junior University Immunomodulation of functional T cell assays for diagnosis of infectious or autoimmune disorders
EP3825688A1 (en) * 2011-04-29 2021-05-26 Cellestis Limited An assay of cell mediated immune responsiveness
US9678071B2 (en) 2012-01-12 2017-06-13 Mayo Foundation For Medical Education And Research Detecting latent tuberculosis infections
WO2013139972A1 (en) * 2012-03-23 2013-09-26 Laboratorios Del Dr. Esteve, S.A. Method for monitoring hiv specific t cell responses
CN102707052B (zh) * 2012-05-11 2015-03-11 中国农业科学院北京畜牧兽医研究所 含重组蛋白混合物的牛结核病检测试剂
SI3421997T1 (sl) * 2012-12-28 2020-10-30 Cellestis Limited Test celično posredovanega imunskega odziva
US11576958B2 (en) 2013-02-07 2023-02-14 Children's Medical Center Corporation Protein antigens that provide protection against pneumococcal colonization and/or disease
US10401360B2 (en) 2013-04-29 2019-09-03 Mayo Foundation For Medical Education And Research Flow cytometry assay methods
CA2923822A1 (en) 2013-09-10 2015-03-19 Immusant, Inc. Dosage of a gluten peptide composition
CN103604933A (zh) * 2013-11-27 2014-02-26 华中科技大学同济医学院附属同济医院 基于抗原特异性TNF-α-ELISA检测活动性结核病的试剂盒及其应用
CA2962933A1 (en) 2014-09-29 2016-04-07 Immusant, Inc. Use of hla genetic status to assess or select treatment of celiac disease
KR20170071507A (ko) 2014-10-23 2017-06-23 퀴아젠 사이언시스, 엘엘씨 펩티드 조성물 및 그의 용도
US10654923B2 (en) 2015-12-28 2020-05-19 Mayo Foundation For Medical Education And Research Methods for treating medical conditions by anti-type 2 therapy
KR20170110297A (ko) * 2016-03-23 2017-10-11 온틀협동조합 천연물 소재의 면역증강 검사법 및 상기 검사법을 활용한 맞춤형 식단 제공방법
KR101777256B1 (ko) 2016-07-07 2017-09-12 대한민국(농림축산식품부 농림축산검역본부장) T 세포의 병원체 감염 세포 독성능 평가 방법
KR101777252B1 (ko) 2016-07-07 2017-09-12 대한민국(농림축산식품부 농림축산검역본부장) T 세포의 prrsv 증식 억제능 평가 방법
US10684275B2 (en) 2016-12-14 2020-06-16 Becton, Dickinson And Company Methods and compositions for obtaining a tuberculosis assessment in a subject
WO2020014703A1 (en) * 2018-07-13 2020-01-16 Excision Biotherapeutics, Inc. Detection of bacterial proteins/immunoglobulins for gene editing therapy
CN119264211A (zh) 2018-08-27 2025-01-07 瑞泽恩制药公司 拉曼光谱在下游纯化中的应用
EP4103234A4 (en) * 2020-02-14 2025-03-12 Epivax, Inc. T-cell epitope clusters and related compounds for the prevention, diagnosis, and treatment of COVID-19
WO2022008973A2 (en) * 2020-07-10 2022-01-13 Covid Diagnostics Ltd. Compositions, methods, and systems for detecting immune response
CN113466000A (zh) * 2021-05-12 2021-10-01 广州医科大学附属肿瘤医院 基于多维度纯化富集技术的恶性胸水检测方法
EP4537103A1 (en) * 2022-06-09 2025-04-16 The Regents of University of California Lymphocyte stimulation assay to quantify immune responses

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US4018653A (en) 1971-10-29 1977-04-19 U.S. Packaging Corporation Instrument for the detection of Neisseria gonorrhoeae without culture
US4016043A (en) 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4424279A (en) 1982-08-12 1984-01-03 Quidel Rapid plunger immunoassay method and apparatus
CA1299099C (en) 1986-03-06 1992-04-21 Paul Richard Wood In vitro assay for detecting cell-mediated immune responses
FR2615622B1 (fr) * 1987-05-19 1994-05-06 Ire Medgenix Sa Dosage plasmatique de monokines
US5693500A (en) * 1988-03-31 1997-12-02 Commonwealth Scientific And Industrial Research Organisation Diagnosis of Mycobacterium bovis infection
FR2645878B1 (fr) * 1989-04-17 1994-02-25 Institut Nal Sante Recherc Medic Sequences nucleotidiques d'actinomycetales, applications a la synthese ou a la detection d'acides nucleiques, produits d'expression de ces sequences et application en tant que compositions immunogenes
US6410252B1 (en) * 1995-12-22 2002-06-25 Case Western Reserve University Methods for measuring T cell cytokines
US5885529A (en) * 1996-06-28 1999-03-23 Dpc Cirrus, Inc. Automated immunoassay analyzer
DE19835721A1 (de) * 1998-08-07 2000-02-10 Edi Experimentelle & Diagnosti Verfahren zur Bestimmung der Immunabwehr des Blutes sowie Testkit hierfür und Verwendung eines geeigneten Spritzenzylinders

Also Published As

Publication number Publication date
JP2006506609A (ja) 2006-02-23
EP1561106A4 (en) 2006-12-27
CA2504829A1 (en) 2004-05-21
EP1561106A1 (en) 2005-08-10
JP4502814B2 (ja) 2010-07-14
WO2004042396A1 (en) 2004-05-21
US20050014205A1 (en) 2005-01-20
EP1561106B1 (en) 2009-04-22
AU2002952548A0 (en) 2002-11-21
DE60327354D1 (de) 2009-06-04
ATE429640T1 (de) 2009-05-15
US7608392B2 (en) 2009-10-27

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Effective date: 20231106