CA2495784A1 - Furanone derivatives and methods of making same - Google Patents
Furanone derivatives and methods of making same Download PDFInfo
- Publication number
- CA2495784A1 CA2495784A1 CA002495784A CA2495784A CA2495784A1 CA 2495784 A1 CA2495784 A1 CA 2495784A1 CA 002495784 A CA002495784 A CA 002495784A CA 2495784 A CA2495784 A CA 2495784A CA 2495784 A1 CA2495784 A1 CA 2495784A1
- Authority
- CA
- Canada
- Prior art keywords
- substituted
- unsubstituted
- compound
- halogen
- arylalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 238000009832 plasma treatment Methods 0.000 description 1
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- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
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- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
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- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
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- 238000001179 sorption measurement Methods 0.000 description 1
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- 239000007921 spray Substances 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
- A01N43/08—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings with oxygen as the ring hetero atom
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/60—Two oxygen atoms, e.g. succinic anhydride
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/66—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Materials For Medical Uses (AREA)
- Cultivation Of Plants (AREA)
- Pyrrole Compounds (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pretreatment Of Seeds And Plants (AREA)
- Absorbent Articles And Supports Therefor (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2002950862 | 2002-08-19 | ||
| AU2002950862A AU2002950862A0 (en) | 2002-08-19 | 2002-08-19 | Furanone derivatives and methods of making same |
| PCT/AU2003/001053 WO2004016588A1 (en) | 2002-08-19 | 2003-08-19 | Furanone derivatives and methods of making same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2495784A1 true CA2495784A1 (en) | 2004-02-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002495784A Abandoned CA2495784A1 (en) | 2002-08-19 | 2003-08-19 | Furanone derivatives and methods of making same |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20050215772A1 (enExample) |
| EP (1) | EP1539692A4 (enExample) |
| JP (1) | JP2006514610A (enExample) |
| CN (1) | CN1688543A (enExample) |
| AU (1) | AU2002950862A0 (enExample) |
| CA (1) | CA2495784A1 (enExample) |
| WO (1) | WO2004016588A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007133777A1 (en) * | 2006-05-15 | 2007-11-22 | Tyco Healthcare Group Lp | Furanone endcapped polymers |
| WO2007133781A3 (en) * | 2006-05-15 | 2008-05-08 | Tyco Healthcare | Furanone-initiated polymers |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007520588A (ja) * | 2003-12-05 | 2007-07-26 | バイオシグナル リミテッド | 抗微生物性化合物と表面およびポリマーとの結合 |
| US7642285B2 (en) * | 2005-02-04 | 2010-01-05 | Wisconsin Alumni Research Foundation | Compounds and methods for modulating communication and virulence in quorum sensing bacteria |
| JP4969065B2 (ja) * | 2005-07-13 | 2012-07-04 | 株式会社 メドレックス | 常温性イオン性液体を含有する医薬組成物 |
| RU2008134473A (ru) | 2006-01-24 | 2010-02-27 | Байосигнал Лимитед (Au) | Новые лактамы |
| AU2015200142B2 (en) * | 2006-01-24 | 2016-07-07 | Unilever Plc | Novel lactams |
| AU2007304839A1 (en) * | 2006-10-06 | 2008-04-10 | Unilever Plc | Furanone compounds and lactam analogues thereof |
| CA2670899C (en) * | 2006-12-01 | 2016-11-22 | Laclede, Inc. | Use of hydrolytic and oxidative enzymes to dissolve biofilm in ears |
| WO2008116029A1 (en) | 2007-03-19 | 2008-09-25 | Wisconsin Alumni Research Foundation | Modulation of bacterial quorum sensing with synthetic ligands |
| CN101503397B (zh) * | 2009-03-23 | 2012-07-18 | 暨南大学 | 卤代呋喃酮化合物及其在制备抗感染药物上的应用 |
| US8624063B2 (en) * | 2009-06-30 | 2014-01-07 | Wisconsin Alumni Research Foundation | Non-lactone carbocyclic and heterocyclic antagonists and agonists of bacterial quorum sensing |
| EP2425862B1 (de) * | 2010-09-07 | 2012-08-29 | Miele & Cie. KG | Verfahren zur Reinigung und thermischen Desinfektion von Spülgut |
| CN102002024B (zh) * | 2010-11-19 | 2012-10-10 | 吉首大学 | 3-芳基-4-芳氨基-2（5h）-呋喃酮型化合物及其制法和用途 |
| AU2013317791B2 (en) | 2012-09-21 | 2018-05-10 | Midwestern University | Inhibitors of beta-hydrolase for treatment of cancer |
| AU2014211458B2 (en) * | 2013-02-01 | 2016-08-11 | Unilever Global Ip Limited | Antimicrobial composition comprising a lactam and a hydrotrope |
| WO2014183164A1 (en) * | 2013-05-17 | 2014-11-20 | Naresh Kumar | Dihydropyrrolones and their use as antimicrobial agents |
| WO2016176146A1 (en) * | 2015-04-26 | 2016-11-03 | The Trustees Of Princeton University | Surfaces comprising attached quorum sensing modulators |
| CN107920977A (zh) * | 2015-08-20 | 2018-04-17 | 荷兰联合利华有限公司 | 内酰胺组合物 |
| US10986837B2 (en) | 2015-08-20 | 2021-04-27 | Conopco, Inc. | Lactam solubility |
| EP3337452B1 (en) | 2015-08-20 | 2024-03-27 | Unilever IP Holdings B.V. | Encapsulated lactams |
| EP3337449B1 (en) * | 2015-08-20 | 2019-09-04 | Unilever PLC, a company registered in England and Wales under company no. 41424 of | Improved lactam solubility |
| TR201901410T4 (tr) * | 2015-08-20 | 2019-02-21 | Unilever Nv | Geliştirilmiş Laktam Çözünürlüğü |
| EP3337450B1 (en) | 2015-08-20 | 2023-05-10 | Unilever IP Holdings B.V. | Improved lactam solubility |
| WO2018015280A1 (en) | 2016-07-21 | 2018-01-25 | Unilever Plc | 4-(4-chlorophenyl)-5-methylene-pyrrol-2-one and 5-methylene-4-(p-tolyl)pyrrol-2-one for use in the treatment of gram negative bacterial infections |
| EP3487494A1 (en) | 2016-07-21 | 2019-05-29 | Unilever PLC | Lactams for the treatment of respiratory tract infections |
| CN109475527A (zh) | 2016-07-21 | 2019-03-15 | 荷兰联合利华有限公司 | 用于治疗皮肤损伤的内酰胺 |
| CN106518818B (zh) * | 2016-10-14 | 2018-07-27 | 宁波大学 | 一种呋喃酮类化合物及其制备方法和用途 |
| BR112019010124A2 (pt) | 2016-11-17 | 2019-08-20 | Unilever Nv | composições de lactama e usos da composição farmacêutica |
| US20190352259A1 (en) | 2016-11-17 | 2019-11-21 | Conopco, Inc., D/B/A Unilever | Lactam compositions |
| US10526278B2 (en) | 2017-10-19 | 2020-01-07 | Wisconsin Alumni Research Foundation | Inhibitors of quorum sensing receptor LasR |
| RU2691634C2 (ru) * | 2017-11-27 | 2019-06-17 | Федеральное Государственное бюджетное научное учреждение Всероссийский научно-исследовательский институт мясного скотоводства | СПОСОБ ПРИМЕНЕНИЯ ГАММА-ОКТАЛАКТОНА В КАЧЕСТВЕ ИНГИБИТОРА СИСТЕМЫ "КВОРУМ СЕНСИНГА" LuxI/LuxR ТИПА У БАКТЕРИЙ |
| CN109705068A (zh) * | 2019-02-27 | 2019-05-03 | 重庆医药高等专科学校 | 原白头翁素合成方法 |
| WO2021214041A1 (en) * | 2020-04-21 | 2021-10-28 | Unilever Ip Holdings B.V. | Varnish |
| EP4168460A1 (en) * | 2020-06-23 | 2023-04-26 | Akzo Nobel Coatings International B.V. | Radiation-curable coating composition, method of coating a substrate and coated substrate |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3755356A (en) * | 1969-11-06 | 1973-08-28 | Zoecon Corp | Substituted crotonic amide ypsilon-lactams |
| AUPM666694A0 (en) * | 1994-07-06 | 1994-07-28 | Unisearch Limited | Natural antifouling compositions |
| AUPQ841900A0 (en) * | 2000-06-28 | 2000-07-20 | Unisearch Limited | Synthesis of cyclic compounds |
-
2002
- 2002-08-19 AU AU2002950862A patent/AU2002950862A0/en not_active Abandoned
-
2003
- 2003-08-19 US US10/525,231 patent/US20050215772A1/en not_active Abandoned
- 2003-08-19 WO PCT/AU2003/001053 patent/WO2004016588A1/en not_active Ceased
- 2003-08-19 JP JP2004528184A patent/JP2006514610A/ja active Pending
- 2003-08-19 CA CA002495784A patent/CA2495784A1/en not_active Abandoned
- 2003-08-19 CN CNA038243997A patent/CN1688543A/zh active Pending
- 2003-08-19 EP EP03787526A patent/EP1539692A4/en not_active Withdrawn
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007133777A1 (en) * | 2006-05-15 | 2007-11-22 | Tyco Healthcare Group Lp | Furanone endcapped polymers |
| WO2007133781A3 (en) * | 2006-05-15 | 2008-05-08 | Tyco Healthcare | Furanone-initiated polymers |
| US7851526B2 (en) | 2006-05-15 | 2010-12-14 | Tyco Healthcare Group Lp | Furanone-initiated polymers |
| US8071691B2 (en) | 2006-05-15 | 2011-12-06 | Tyco Healthcare Group Lp | Furanone endcapped polymers |
| AU2007249766B2 (en) * | 2006-05-15 | 2012-08-23 | Covidien Lp | Furanone endcapped polymers |
| AU2007249679B2 (en) * | 2006-05-15 | 2012-11-01 | Covidien Lp | Furanone-initiated polymers |
Also Published As
| Publication number | Publication date |
|---|---|
| US20050215772A1 (en) | 2005-09-29 |
| AU2002950862A0 (en) | 2002-09-12 |
| EP1539692A1 (en) | 2005-06-15 |
| EP1539692A4 (en) | 2005-08-24 |
| WO2004016588A1 (en) | 2004-02-26 |
| CN1688543A (zh) | 2005-10-26 |
| JP2006514610A (ja) | 2006-05-11 |
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