CA2486584A1 - Compositions and methods for treating diabetes - Google Patents
Compositions and methods for treating diabetes Download PDFInfo
- Publication number
- CA2486584A1 CA2486584A1 CA002486584A CA2486584A CA2486584A1 CA 2486584 A1 CA2486584 A1 CA 2486584A1 CA 002486584 A CA002486584 A CA 002486584A CA 2486584 A CA2486584 A CA 2486584A CA 2486584 A1 CA2486584 A1 CA 2486584A1
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- Prior art keywords
- agent
- composition
- medicament
- immune response
- receptor ligand
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Transplantation (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38703202P | 2002-06-07 | 2002-06-07 | |
| US60/387,032 | 2002-06-07 | ||
| US43059002P | 2002-12-03 | 2002-12-03 | |
| US60/430,590 | 2002-12-03 | ||
| PCT/US2003/018377 WO2003103701A1 (en) | 2002-06-07 | 2003-06-09 | Compositions and methods for treating diabetes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2486584A1 true CA2486584A1 (en) | 2003-12-18 |
Family
ID=29739925
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002486584A Abandoned CA2486584A1 (en) | 2002-06-07 | 2003-06-09 | Compositions and methods for treating diabetes |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US7560425B2 (enExample) |
| EP (1) | EP1511509B1 (enExample) |
| JP (1) | JP2005533775A (enExample) |
| KR (1) | KR20050048542A (enExample) |
| CN (1) | CN1671407B (enExample) |
| AT (2) | ATE375166T1 (enExample) |
| AU (1) | AU2003243501A1 (enExample) |
| CA (1) | CA2486584A1 (enExample) |
| DE (2) | DE60329724D1 (enExample) |
| ES (1) | ES2334268T3 (enExample) |
| IL (2) | IL165285A0 (enExample) |
| WO (1) | WO2003103701A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006002532A1 (en) * | 2004-07-01 | 2006-01-12 | Waratah Pharmaceuticals, Inc. | Methods and compositions using cd3 agonists |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6558952B1 (en) * | 1992-12-14 | 2003-05-06 | Waratah Pharmaceuticals, Inc. | Treatment for diabetes |
| GB9409496D0 (en) * | 1994-05-12 | 1994-06-29 | London Health Ass | Method for improving glycaemic control in diabetes |
| ES2315350T3 (es) | 2001-01-12 | 2009-04-01 | Waratah Pharmaceuticals Inc. | Composiciones para la introduccion de la neogenesis de islotes, que contienen unos ligandos para el receptor de gastrina/cck y ligandos para el receptor de efg. |
| US7037504B2 (en) * | 2001-10-23 | 2006-05-02 | Waratah Pharmaceuticals, Inc. | Epidermal growth factor protein and gene, and methods of use therefor |
| JP2005527224A (ja) * | 2002-05-24 | 2005-09-15 | ワラタ ファーマシューティカルズ， インコーポレイテッド | 糖尿病の処置 |
| CA2486584A1 (en) | 2002-06-07 | 2003-12-18 | Waratah Pharmaceuticals, Inc. | Compositions and methods for treating diabetes |
| EP1837031B1 (en) | 2002-06-07 | 2009-10-14 | Waratah Pharmaceuticals, Inc. | Compositions and methods for treating diabetes |
| US20040229810A1 (en) * | 2002-10-22 | 2004-11-18 | Antonio Cruz | Gastrin compositions and formulations, and methods of use and preparation |
| KR20060006058A (ko) * | 2003-04-22 | 2006-01-18 | 와이어쓰 | 항신생물성 배합물 |
| US20080039379A1 (en) * | 2003-05-27 | 2008-02-14 | Waratah Pharmaceuticals, Inc. | Compositions Comprising Gastrin Compounds and Their Use in Diabetes |
| BRPI0507189A (pt) * | 2004-01-30 | 2007-06-26 | Waratah Pharmaceuticals Inc | uso combinado de um agonista de glp-1 e compostos de gastrina |
| US8268791B2 (en) * | 2004-08-25 | 2012-09-18 | Aegis Therapeutics, Llc. | Alkylglycoside compositions for drug administration |
| US20140162965A1 (en) | 2004-08-25 | 2014-06-12 | Aegis Therapeutics, Inc. | Compositions for oral drug administration |
| US9895444B2 (en) | 2004-08-25 | 2018-02-20 | Aegis Therapeutics, Llc | Compositions for drug administration |
| US20060046962A1 (en) | 2004-08-25 | 2006-03-02 | Aegis Therapeutics Llc | Absorption enhancers for drug administration |
| CN104206651A (zh) * | 2004-12-30 | 2014-12-17 | 希尔氏宠物营养品公司 | 用于猫消费的组合物 |
| EP1951286A4 (en) * | 2005-10-07 | 2009-11-04 | Waratah Pharmaceuticals Inc | COMBINED USE OF INHIBITORS OF DPP-IV AND GASTRIN COMPOUNDS |
| US10137083B2 (en) * | 2006-03-07 | 2018-11-27 | SGN Nanopharma Inc | Ophthalmic preparations |
| US11311477B2 (en) * | 2006-03-07 | 2022-04-26 | Sgn Nanopharma Inc. | Ophthalmic preparations |
| US8226949B2 (en) | 2006-06-23 | 2012-07-24 | Aegis Therapeutics Llc | Stabilizing alkylglycoside compositions and methods thereof |
| US8173594B2 (en) * | 2006-06-23 | 2012-05-08 | Aegis Therapeutics, Llc | Stabilizing alkylglycoside compositions and methods thereof |
| US20090326193A1 (en) * | 2006-06-23 | 2009-12-31 | Aegis Therapeutics Llc | Stabilizing alkylglycoside compositions and methods thereof |
| US8084022B2 (en) * | 2006-06-23 | 2011-12-27 | Aegis Therapeutics, Llc | Stabilizing alkylglycoside compositions and methods thereof |
| US7425542B2 (en) * | 2006-06-23 | 2008-09-16 | Aegis Therapeutics, Inc. | Stabilizing alkylglycoside compositions and methods thereof |
| US7998927B2 (en) * | 2006-06-23 | 2011-08-16 | Aegis Therapeutics, Llc | Stabilizing alkylglycoside compositions and methods thereof |
| EP2040737A4 (en) * | 2006-07-14 | 2013-05-29 | Postech Acad Ind Found | EPIDERMAL GROWTH FACTOR FOR INCREASING INSULIN SECRETION AND REDUCING BLOOD SUGAR |
| US20090258865A1 (en) | 2008-03-28 | 2009-10-15 | Hale Biopharma Ventures, Llc | Administration of benzodiazepine compositions |
| CA2732228A1 (en) * | 2008-07-25 | 2010-01-28 | The Johns Hopkins University | Methods and compositions for treating and preventing autoimmune diseases |
| US8440631B2 (en) | 2008-12-22 | 2013-05-14 | Aegis Therapeutics, Llc | Compositions for drug administration |
| US8940705B2 (en) | 2009-01-09 | 2015-01-27 | The Regents Of The University Of California | Method of treating disease and selectively modulating transcriptional regulation by a glucocorticoid receptor by administering aclacinomycin and dexamethasone |
| PT3415139T (pt) | 2011-06-14 | 2022-06-20 | Neurelis Inc | Administração de benzodiazepina |
| HK1198467A1 (en) * | 2011-08-03 | 2015-05-08 | Zhongmin MA | Treatment of type 2 diabetes with fty720 |
| US20130273089A1 (en) | 2011-11-03 | 2013-10-17 | Tolera Therapeutics, Inc. | Antibody and methods for selective inhibition of t-cell responses |
| BR112014010532A2 (pt) | 2011-11-03 | 2017-04-18 | Tolera Therapeutics Inc | anticorpo e métodos para inibição seletiva de respostas de célula-t |
| WO2014138003A1 (en) * | 2013-03-04 | 2014-09-12 | Neuralstem, Inc. | Compositions comprising an immunosuppressive drug and/or neural stem cells and methods of using same for the treatment of neurodegenerative diseases and/or disorders |
| US11116777B2 (en) | 2015-11-10 | 2021-09-14 | City Of Hope | Conditioning regimens and methods for inducing mixed chimerism |
| WO2017116569A1 (en) * | 2015-12-31 | 2017-07-06 | City Of Hope | Methods for treating diabetes |
| US20210355448A1 (en) * | 2017-06-26 | 2021-11-18 | City Of Hope | Methods of islet cell culture |
| IL280198B2 (en) * | 2018-07-18 | 2026-01-01 | Regenxbio Inc | Treatment of mucopolysaccharidosis I with fully glycosylated human iduronidase-alpha-L (idus) |
| JP7137696B2 (ja) | 2019-05-14 | 2022-09-14 | プロヴェンション・バイオ・インコーポレイテッド | １型糖尿病を予防するための方法および組成物 |
| KR20230092863A (ko) | 2020-06-11 | 2023-06-26 | 프로벤션 바이오, 인코포레이티드 | 제1형 당뇨병을 예방하기 위한 방법 및 조성물 |
| MX2023013851A (es) | 2021-05-24 | 2023-12-08 | Provention Bio Inc | Metodos para el tratamiento de diabetes tipo 1. |
| EP4376866A4 (en) * | 2021-06-10 | 2025-10-08 | Fouad Kandeel | COMPOSITIONS AND METHODS FOR ISLET OF LANGERHANS TRANSPLANTS |
| CA3221395A1 (en) | 2021-06-10 | 2022-12-15 | Neurelis, Inc. | Methods and compositions for treating seizure disorders in pediatric patients |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL101353A0 (en) | 1991-04-03 | 1992-11-15 | American Home Prod | Pharmaceutical compositions for treating diabetes |
| DK36392D0 (da) | 1992-03-19 | 1992-03-19 | Novo Nordisk As | Anvendelse af kemisk forbindelse |
| US5885956A (en) * | 1992-12-14 | 1999-03-23 | Research Triangle Pharmaceuticals | Treatment for diabetes using a gastrin/CCK receptor ligand and an EGF receptor ligand |
| US6558952B1 (en) | 1992-12-14 | 2003-05-06 | Waratah Pharmaceuticals, Inc. | Treatment for diabetes |
| ES2185663T3 (es) * | 1994-01-24 | 2003-05-01 | Waratah Pharmaceuticals Inc | Tratamiento de la diabetes. |
| US5624895A (en) * | 1994-02-18 | 1997-04-29 | Georgetown University Medical Center | Treatment and/or prevention of type I diabetes mellitus with gamma interferon administration |
| GB9409496D0 (en) | 1994-05-12 | 1994-06-29 | London Health Ass | Method for improving glycaemic control in diabetes |
| US20040037818A1 (en) | 1998-07-30 | 2004-02-26 | Brand Stephen J. | Treatment for diabetes |
| AU5027299A (en) | 1998-07-31 | 2000-02-28 | Novo Nordisk A/S | Use of glp-1 and analogues for preventing type ii diabetes |
| US6610535B1 (en) | 2000-02-10 | 2003-08-26 | Es Cell International Pte Ltd. | Progenitor cells and methods and uses related thereto |
| JP2003528135A (ja) | 2000-03-31 | 2003-09-24 | プロバイオドラッグ アーゲー | 糖尿病のランゲルハンス島シグナリングの改善方法及びその防止方法 |
| ES2315350T3 (es) | 2001-01-12 | 2009-04-01 | Waratah Pharmaceuticals Inc. | Composiciones para la introduccion de la neogenesis de islotes, que contienen unos ligandos para el receptor de gastrina/cck y ligandos para el receptor de efg. |
| ES2298378T3 (es) | 2001-06-28 | 2008-05-16 | Novo Nordisk A/S | Formulacion estable de glp-1 modificado. |
| US7037504B2 (en) * | 2001-10-23 | 2006-05-02 | Waratah Pharmaceuticals, Inc. | Epidermal growth factor protein and gene, and methods of use therefor |
| JP2005527224A (ja) | 2002-05-24 | 2005-09-15 | ワラタ ファーマシューティカルズ， インコーポレイテッド | 糖尿病の処置 |
| WO2004105780A2 (en) | 2003-05-27 | 2004-12-09 | Waratah Pharmaceuticals, Inc. | Compositions comprising gastrin compounds and their use in diabetes |
| EP1837031B1 (en) | 2002-06-07 | 2009-10-14 | Waratah Pharmaceuticals, Inc. | Compositions and methods for treating diabetes |
| CA2486584A1 (en) | 2002-06-07 | 2003-12-18 | Waratah Pharmaceuticals, Inc. | Compositions and methods for treating diabetes |
| MXPA05004202A (es) | 2002-10-22 | 2005-09-20 | Waratah Pharmaceuticals Inc | Tratamiento de la diabetes. |
| US20040229810A1 (en) | 2002-10-22 | 2004-11-18 | Antonio Cruz | Gastrin compositions and formulations, and methods of use and preparation |
| JP2007523840A (ja) | 2003-04-30 | 2007-08-23 | ワラタ ファーマシューティカルズ， インコーポレイテッド | ケラチノサイト増殖因子アゴニストおよびカストリン化合物を組み合わせた使用 |
| BRPI0507189A (pt) | 2004-01-30 | 2007-06-26 | Waratah Pharmaceuticals Inc | uso combinado de um agonista de glp-1 e compostos de gastrina |
| WO2006002532A1 (en) | 2004-07-01 | 2006-01-12 | Waratah Pharmaceuticals, Inc. | Methods and compositions using cd3 agonists |
| EP1951286A4 (en) | 2005-10-07 | 2009-11-04 | Waratah Pharmaceuticals Inc | COMBINED USE OF INHIBITORS OF DPP-IV AND GASTRIN COMPOUNDS |
| WO2007062531A1 (en) | 2005-12-02 | 2007-06-07 | Waratah Pharmaceuticals, Inc. | Combination treatments with gastrin agonists for diabetes and related diseases |
| WO2007095737A1 (en) | 2006-02-21 | 2007-08-30 | Waratah Pharmaceuticals Inc. | Combination therapy for the treatment of diabetes comprising an exendin agonist and a gastrin compound |
-
2003
- 2003-06-09 CA CA002486584A patent/CA2486584A1/en not_active Abandoned
- 2003-06-09 AT AT03757483T patent/ATE375166T1/de not_active IP Right Cessation
- 2003-06-09 IL IL16528503A patent/IL165285A0/xx unknown
- 2003-06-09 US US10/517,135 patent/US7560425B2/en not_active Expired - Fee Related
- 2003-06-09 KR KR1020047019788A patent/KR20050048542A/ko not_active Ceased
- 2003-06-09 CN CN038185261A patent/CN1671407B/zh not_active Expired - Fee Related
- 2003-06-09 AU AU2003243501A patent/AU2003243501A1/en not_active Abandoned
- 2003-06-09 WO PCT/US2003/018377 patent/WO2003103701A1/en not_active Ceased
- 2003-06-09 EP EP03757483A patent/EP1511509B1/en not_active Expired - Lifetime
- 2003-06-09 ES ES07010865T patent/ES2334268T3/es not_active Expired - Lifetime
- 2003-06-09 AT AT07010865T patent/ATE445407T1/de not_active IP Right Cessation
- 2003-06-09 JP JP2004510820A patent/JP2005533775A/ja active Pending
- 2003-06-09 DE DE60329724T patent/DE60329724D1/de not_active Expired - Lifetime
- 2003-06-09 US US10/457,126 patent/US20040023885A1/en not_active Abandoned
- 2003-06-09 DE DE60316798T patent/DE60316798T2/de not_active Expired - Lifetime
-
2004
- 2004-11-18 IL IL165285A patent/IL165285A/en not_active IP Right Cessation
-
2009
- 2009-04-08 US US12/420,212 patent/US20090269337A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006002532A1 (en) * | 2004-07-01 | 2006-01-12 | Waratah Pharmaceuticals, Inc. | Methods and compositions using cd3 agonists |
Also Published As
| Publication number | Publication date |
|---|---|
| US7560425B2 (en) | 2009-07-14 |
| KR20050048542A (ko) | 2005-05-24 |
| IL165285A (en) | 2010-04-29 |
| US20060183674A1 (en) | 2006-08-17 |
| JP2005533775A (ja) | 2005-11-10 |
| DE60316798D1 (de) | 2007-11-22 |
| CN1671407A (zh) | 2005-09-21 |
| DE60329724D1 (de) | 2009-11-26 |
| ES2334268T3 (es) | 2010-03-08 |
| US20090269337A1 (en) | 2009-10-29 |
| US20040023885A1 (en) | 2004-02-05 |
| ATE375166T1 (de) | 2007-10-15 |
| EP1511509A1 (en) | 2005-03-09 |
| EP1511509A4 (en) | 2005-04-27 |
| DE60316798T2 (de) | 2008-07-24 |
| ATE445407T1 (de) | 2009-10-15 |
| IL165285A0 (en) | 2005-12-18 |
| AU2003243501A1 (en) | 2003-12-22 |
| WO2003103701A1 (en) | 2003-12-18 |
| CN1671407B (zh) | 2010-05-26 |
| EP1511509B1 (en) | 2007-10-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |