CA2484724C - Formulations pharmaceutiques - Google Patents

Formulations pharmaceutiques Download PDF

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Publication number
CA2484724C
CA2484724C CA002484724A CA2484724A CA2484724C CA 2484724 C CA2484724 C CA 2484724C CA 002484724 A CA002484724 A CA 002484724A CA 2484724 A CA2484724 A CA 2484724A CA 2484724 C CA2484724 C CA 2484724C
Authority
CA
Canada
Prior art keywords
dosage form
desmopressin
desmopressin acetate
water
solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002484724A
Other languages
English (en)
Other versions
CA2484724A1 (fr
Inventor
Anders Nilsson
Hans Lindner
Jorgen Wittendorff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferring BV
Original Assignee
Ferring BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0210397.6A external-priority patent/GB0210397D0/en
Application filed by Ferring BV filed Critical Ferring BV
Publication of CA2484724A1 publication Critical patent/CA2484724A1/fr
Application granted granted Critical
Publication of CA2484724C publication Critical patent/CA2484724C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2063—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

On peut obtenir de la desmopressine présentant une bonne biodisponibilité au moyen d'une forme posologique pouvant se disperser dans la bouche. Les formes posologiques préférées comportent de la desmopressine et un réseau matriciel ouvert du type support hydrosoluble inerte ou pouvant se disperser dans l'eau. La desmopressine ainsi formulée peut servir à retarder la miction ou à traiter ou prévenir l'incontinence, l'énurésie nocturne primaire, la nycturie ou le diabète insipide d'origine centrale. On peut également formuler de cette manière des peptides autres que la desmopressine.
CA002484724A 2002-05-07 2003-05-07 Formulations pharmaceutiques Expired - Lifetime CA2484724C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB0210397.6A GB0210397D0 (en) 2002-05-07 2002-05-07 Pharmaceutical formulations
GB0210397.6 2002-05-07
IBPCT/IB02/04036 2002-09-20
PCT/IB2002/004036 WO2003094885A1 (fr) 2002-05-07 2002-09-20 Formulation pharmaceutique sublinguale a base de desmopressine
PCT/IB2003/002368 WO2003094886A2 (fr) 2002-05-07 2003-05-07 Preparations pharmaceutiques

Publications (2)

Publication Number Publication Date
CA2484724A1 CA2484724A1 (fr) 2003-11-20
CA2484724C true CA2484724C (fr) 2007-01-16

Family

ID=29422105

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002484724A Expired - Lifetime CA2484724C (fr) 2002-05-07 2003-05-07 Formulations pharmaceutiques

Country Status (10)

Country Link
JP (1) JP2006502972A (fr)
AU (1) AU2003233118B8 (fr)
BR (1) BR0309819A (fr)
CA (1) CA2484724C (fr)
DE (2) DE60307082D1 (fr)
HR (1) HRP20041152B1 (fr)
NO (1) NO335167B1 (fr)
NZ (1) NZ535861A (fr)
PT (1) PT1501534E (fr)
WO (1) WO2003094886A2 (fr)

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US7094545B2 (en) 2003-04-30 2006-08-22 Ferring Bv Pharmaceutical composition as solid dosage form and method for manufacturing thereof
DE60301351T2 (de) 2003-07-25 2006-01-19 Ferring B.V. Pharmazeutische Desmopressin-Zubereitung als feste Darreichungsform und Methode zu ihrer Herstellung
EP2322195A2 (fr) * 2003-11-10 2011-05-18 Reprise Biopharmaceutics, LLC Compositions pharmaceutiques comportant de la desmopressine faiblement dosee
PT1530967E (pt) * 2003-11-13 2006-09-29 Ferring Bv Embalagem blister e uma forma de dosagem solida que compreende desmopressina.
US7018653B2 (en) 2003-12-29 2006-03-28 Ferring B.V. Method for preparing solid dosage form of desmopressin
CA2490601C (fr) * 2003-12-29 2006-05-02 Ferring B.V. Methode de preparation d'une forme pharmaceutique solide de desmopressine
ES2254858T3 (es) * 2003-12-29 2006-06-16 Ferring B.V. Metodo para preparar una forma farmaceutica solida de desmopresina.
GB0406048D0 (en) * 2004-03-18 2004-04-21 Ardana Bioscience Ltd Drug formulations
US7972621B2 (en) * 2004-06-03 2011-07-05 R.P. Scherer Technologies, Llc Process for formulating fast dispersing dosage forms comprising at least one fish gelatin selected on the basis of molecular weight
SE0600482L (sv) * 2006-03-02 2006-11-14 Ferring Int Ct Sa Farmaceutisk sammansättning innefattande desmopressin, kiseldioxid och stärkelse
CA2584456C (fr) * 2006-03-02 2008-07-22 Ferring International Center S.A. Composition avec desmopressine
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ES2710454T3 (es) 2008-05-21 2019-04-25 Ferring Bv Desmopresina bucodispersable para aumentar el periodo inicial de sueño ininterrumpido por nocturia
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
US20100286045A1 (en) * 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
WO2010059836A1 (fr) 2008-11-20 2010-05-27 Decode Genetics Ehf Composés bicycliques substitués à pont aza pour maladie cardiovasculaire et du système nerveux central
EP2389383B1 (fr) 2009-01-26 2019-04-24 Israel Institute For Biological Research Composés spiro hétérocycliques bicycliques
TWI471127B (zh) 2009-04-29 2015-02-01 Intervet Int Bv 供人類使用之口服崩解錠劑的製備方法、所製得之口服崩解錠劑、以及含有該口服崩解錠劑的包裝物
TWI468157B (zh) * 2009-04-29 2015-01-11 Intervet Int Bv 形成錠劑的方法，進行該方法的系統及包含該錠劑的包裝物
PL3679941T3 (pl) 2009-06-18 2023-04-17 Serenity Pharmaceuticals Llc Bezpieczne podawanie desmopresyny
WO2011008572A2 (fr) 2009-07-14 2011-01-20 Albany Molecular Research, Inc. Modulateurs du récepteur 5-ht3, procédés de fabrication et d'utilisation de ceux-ci
US10548839B2 (en) 2010-03-16 2020-02-04 Wei Tian Process of manufacturing a lyophilized fast dissolving, multi-phasic dosage form
NZ619857A (en) 2010-03-29 2015-05-29 Ferring Bv A fast dissolving pharmaceutical composition
JO3112B1 (ar) * 2010-03-29 2017-09-20 Ferring Bv تركيبة دوائية سريعة التحلل
KR101751964B1 (ko) * 2010-10-08 2017-06-28 알.피.쉐러 테크놀러지즈 엘엘씨 전분을 이용한 경구 백신 급속 용해성 투여 형태
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CN103993061B (zh) * 2014-05-20 2018-03-23 海南美合泰生物科技有限公司 一种鱼胶原蛋白的生产方法
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JP6341777B2 (ja) * 2014-06-30 2018-06-13 リプリーズ バイオファーマシューティクス，エルエルシー 低用量デスモプレシンを含有する医薬組成物
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Also Published As

Publication number Publication date
BR0309819A (pt) 2005-03-01
AU2003233118B2 (en) 2006-10-26
CA2484724A1 (fr) 2003-11-20
WO2003094886A3 (fr) 2004-07-22
WO2003094886A2 (fr) 2003-11-20
AU2003233118B8 (en) 2009-07-30
HRP20041152B1 (en) 2008-01-31
JP2006502972A (ja) 2006-01-26
NO335167B1 (no) 2014-10-06
DE60307082T4 (de) 2015-04-30
DE60307082T2 (de) 2007-01-18
AU2003233118A1 (en) 2003-11-11
NZ535861A (en) 2006-11-30
PT1501534E (pt) 2006-09-29
DE60307082D1 (de) 2006-09-07
NO20045345L (no) 2005-02-07
HRP20041152A2 (en) 2005-04-30

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Effective date: 20230508