CA2476896A1 - Inhibition of inflammatory cytokine production by stimulation of brain muscarinic receptors - Google Patents

Inhibition of inflammatory cytokine production by stimulation of brain muscarinic receptors Download PDF

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Publication number
CA2476896A1
CA2476896A1 CA002476896A CA2476896A CA2476896A1 CA 2476896 A1 CA2476896 A1 CA 2476896A1 CA 002476896 A CA002476896 A CA 002476896A CA 2476896 A CA2476896 A CA 2476896A CA 2476896 A1 CA2476896 A1 CA 2476896A1
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Prior art keywords
vertebrate
disease
brain
pro
inflammatory
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Abandoned
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CA002476896A
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English (en)
French (fr)
Inventor
Svetlana M. Ivanova
Kevin J. Tracey
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Feinstein Institutes for Medical Research
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • A61K41/17—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • AIDS & HIV (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
CA002476896A 2002-02-26 2003-02-26 Inhibition of inflammatory cytokine production by stimulation of brain muscarinic receptors Abandoned CA2476896A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36008202P 2002-02-26 2002-02-26
US60/360,082 2002-02-26
PCT/US2003/005873 WO2003072135A2 (en) 2002-02-26 2003-02-26 Inhibition of inflammatory cytokine production by stimulation of brain muscarinic receptors

Publications (1)

Publication Number Publication Date
CA2476896A1 true CA2476896A1 (en) 2003-09-04

Family

ID=27766183

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002476896A Abandoned CA2476896A1 (en) 2002-02-26 2003-02-26 Inhibition of inflammatory cytokine production by stimulation of brain muscarinic receptors

Country Status (6)

Country Link
US (2) US20040048795A1 (https=)
EP (1) EP1487494A2 (https=)
JP (1) JP2005522457A (https=)
AU (1) AU2003217747A1 (https=)
CA (1) CA2476896A1 (https=)
WO (1) WO2003072135A2 (https=)

Cited By (1)

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