CA2468192A1 - Peptidomimetic inhibitors of post-proline cleaving enzymes - Google Patents
Peptidomimetic inhibitors of post-proline cleaving enzymes Download PDFInfo
- Publication number
- CA2468192A1 CA2468192A1 CA002468192A CA2468192A CA2468192A1 CA 2468192 A1 CA2468192 A1 CA 2468192A1 CA 002468192 A CA002468192 A CA 002468192A CA 2468192 A CA2468192 A CA 2468192A CA 2468192 A1 CA2468192 A1 CA 2468192A1
- Authority
- CA
- Canada
- Prior art keywords
- hydrogen
- inhibitor
- alkyl
- alkenyl
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
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Landscapes
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2837936A CA2837936A1 (en) | 2001-11-26 | 2002-11-26 | Peptidomimetic inhibitors of post-proline cleaving enzymes |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33351901P | 2001-11-26 | 2001-11-26 | |
| US60/333,519 | 2001-11-26 | ||
| US40553002P | 2002-08-23 | 2002-08-23 | |
| US60/405,530 | 2002-08-23 | ||
| PCT/US2002/038053 WO2003045977A2 (en) | 2001-11-26 | 2002-11-26 | Peptidomimetic Inhibitors of Post-Proline Cleaving Enzymes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2837936A Division CA2837936A1 (en) | 2001-11-26 | 2002-11-26 | Peptidomimetic inhibitors of post-proline cleaving enzymes |
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| CA2468192A1 true CA2468192A1 (en) | 2003-06-05 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2837936A Abandoned CA2837936A1 (en) | 2001-11-26 | 2002-11-26 | Peptidomimetic inhibitors of post-proline cleaving enzymes |
| CA002468192A Abandoned CA2468192A1 (en) | 2001-11-26 | 2002-11-26 | Peptidomimetic inhibitors of post-proline cleaving enzymes |
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| CA2837936A Abandoned CA2837936A1 (en) | 2001-11-26 | 2002-11-26 | Peptidomimetic inhibitors of post-proline cleaving enzymes |
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| Country | Link |
|---|---|
| US (4) | US7727964B2 (enExample) |
| EP (2) | EP1469873A4 (enExample) |
| JP (3) | JP4771661B2 (enExample) |
| AU (1) | AU2002357767C1 (enExample) |
| CA (2) | CA2837936A1 (enExample) |
| WO (1) | WO2003045977A2 (enExample) |
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| DE10150203A1 (de) * | 2001-10-12 | 2003-04-17 | Probiodrug Ag | Peptidylketone als Inhibitoren der DPIV |
| US6634939B2 (en) * | 2001-08-31 | 2003-10-21 | Thomas W. Johnson | Ventilation system and method |
| AU2002360453C1 (en) * | 2001-11-26 | 2009-06-18 | The Brigham And Women's Hospital, Inc. | Methods for treating autoimmune disorders, and reagents related thereto |
| CA2837936A1 (en) | 2001-11-26 | 2003-06-05 | Trustees Of Tufts College | Peptidomimetic inhibitors of post-proline cleaving enzymes |
| US7691967B2 (en) * | 2002-04-30 | 2010-04-06 | Trustees Of Tufts College | Smart pro-drugs of serine protease inhibitors |
| AU2003248921A1 (en) * | 2002-07-09 | 2004-01-23 | Point Therapeutics, Inc. | Boroproline compound combination therapy |
| WO2004103390A2 (en) * | 2003-05-15 | 2004-12-02 | Trustees Of Tufts College | Stable analogs of peptide and polypeptide therapeutics |
| BRPI0507972A (pt) * | 2004-02-23 | 2007-07-24 | Tufts College | composto ,composição farmacêutica , uso de um composto, método para inibição da atividade proteolìtica de uma enzima de clivagem pós prolina e composição farmacêutica embalada |
| US20060063719A1 (en) * | 2004-09-21 | 2006-03-23 | Point Therapeutics, Inc. | Methods for treating diabetes |
-
2002
- 2002-11-26 CA CA2837936A patent/CA2837936A1/en not_active Abandoned
- 2002-11-26 EP EP02792306A patent/EP1469873A4/en not_active Withdrawn
- 2002-11-26 EP EP10011373A patent/EP2316470A3/en not_active Withdrawn
- 2002-11-26 US US10/496,706 patent/US7727964B2/en not_active Expired - Lifetime
- 2002-11-26 CA CA002468192A patent/CA2468192A1/en not_active Abandoned
- 2002-11-26 WO PCT/US2002/038053 patent/WO2003045977A2/en not_active Ceased
- 2002-11-26 AU AU2002357767A patent/AU2002357767C1/en not_active Ceased
- 2002-11-26 JP JP2003547426A patent/JP4771661B2/ja not_active Expired - Fee Related
-
2010
- 2010-06-01 US US12/791,517 patent/US20110082108A1/en not_active Abandoned
-
2011
- 2011-03-02 JP JP2011045147A patent/JP2011121989A/ja active Pending
-
2014
- 2014-02-24 JP JP2014033295A patent/JP2014139191A/ja not_active Abandoned
-
2016
- 2016-02-12 US US15/043,110 patent/US9757400B2/en not_active Expired - Fee Related
-
2017
- 2017-06-19 US US15/626,254 patent/US20170333461A1/en not_active Abandoned
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7674913B2 (en) | 2003-11-12 | 2010-03-09 | Phenomix Corporation | Heterocyclic boronic acid compounds |
| US7767828B2 (en) | 2003-11-12 | 2010-08-03 | Phenomix Corporation | Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| US7884217B2 (en) | 2003-11-12 | 2011-02-08 | Phenomix Corporation | Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| US7906658B2 (en) | 2003-11-12 | 2011-03-15 | Phenomix Corporation | Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| US8415295B2 (en) | 2003-11-12 | 2013-04-09 | Phenomix Corporation | Heterocyclic boronic acid compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| US20050070482A1 (en) | 2005-03-31 |
| JP2005514377A (ja) | 2005-05-19 |
| EP2316470A2 (en) | 2011-05-04 |
| CA2837936A1 (en) | 2003-06-05 |
| EP1469873A4 (en) | 2007-10-03 |
| EP2316470A3 (en) | 2011-08-24 |
| US9757400B2 (en) | 2017-09-12 |
| US20160158260A1 (en) | 2016-06-09 |
| JP4771661B2 (ja) | 2011-09-14 |
| WO2003045977A2 (en) | 2003-06-05 |
| AU2002357767B2 (en) | 2008-12-04 |
| JP2014139191A (ja) | 2014-07-31 |
| EP1469873A2 (en) | 2004-10-27 |
| US20170333461A1 (en) | 2017-11-23 |
| AU2002357767A1 (en) | 2003-06-10 |
| AU2002357767C1 (en) | 2009-03-19 |
| US20110082108A1 (en) | 2011-04-07 |
| JP2011121989A (ja) | 2011-06-23 |
| WO2003045977A3 (en) | 2004-05-13 |
| US7727964B2 (en) | 2010-06-01 |
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