CA2468192A1 - Peptidomimetic inhibitors of post-proline cleaving enzymes - Google Patents
Peptidomimetic inhibitors of post-proline cleaving enzymes Download PDFInfo
- Publication number
- CA2468192A1 CA2468192A1 CA002468192A CA2468192A CA2468192A1 CA 2468192 A1 CA2468192 A1 CA 2468192A1 CA 002468192 A CA002468192 A CA 002468192A CA 2468192 A CA2468192 A CA 2468192A CA 2468192 A1 CA2468192 A1 CA 2468192A1
- Authority
- CA
- Canada
- Prior art keywords
- hydrogen
- inhibitor
- alkyl
- alkenyl
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Landscapes
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- Endocrinology (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2837936A CA2837936A1 (en) | 2001-11-26 | 2002-11-26 | Peptidomimetic inhibitors of post-proline cleaving enzymes |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33351901P | 2001-11-26 | 2001-11-26 | |
| US60/333,519 | 2001-11-26 | ||
| US40553002P | 2002-08-23 | 2002-08-23 | |
| US60/405,530 | 2002-08-23 | ||
| PCT/US2002/038053 WO2003045977A2 (en) | 2001-11-26 | 2002-11-26 | Peptidomimetic Inhibitors of Post-Proline Cleaving Enzymes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2837936A Division CA2837936A1 (en) | 2001-11-26 | 2002-11-26 | Peptidomimetic inhibitors of post-proline cleaving enzymes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2468192A1 true CA2468192A1 (en) | 2003-06-05 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002468192A Abandoned CA2468192A1 (en) | 2001-11-26 | 2002-11-26 | Peptidomimetic inhibitors of post-proline cleaving enzymes |
| CA2837936A Abandoned CA2837936A1 (en) | 2001-11-26 | 2002-11-26 | Peptidomimetic inhibitors of post-proline cleaving enzymes |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2837936A Abandoned CA2837936A1 (en) | 2001-11-26 | 2002-11-26 | Peptidomimetic inhibitors of post-proline cleaving enzymes |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US7727964B2 (enExample) |
| EP (2) | EP2316470A3 (enExample) |
| JP (3) | JP4771661B2 (enExample) |
| AU (1) | AU2002357767C1 (enExample) |
| CA (2) | CA2468192A1 (enExample) |
| WO (1) | WO2003045977A2 (enExample) |
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| US7767828B2 (en) | 2003-11-12 | 2010-08-03 | Phenomix Corporation | Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| US7884217B2 (en) | 2003-11-12 | 2011-02-08 | Phenomix Corporation | Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
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| EP2316470A3 (en) | 2001-11-26 | 2011-08-24 | Trustees Of Tufts College | Peptidomimetic inhibitors of post-proline cleaving enzymes |
| CA2484551A1 (en) * | 2002-04-30 | 2003-11-13 | Trustees Of Tufts College | Smart pro-drugs of serine protease inhibitors |
| AU2003248921A1 (en) | 2002-07-09 | 2004-01-23 | Point Therapeutics, Inc. | Boroproline compound combination therapy |
| CN1822851B (zh) | 2003-05-15 | 2011-04-13 | 塔夫茨大学信托人 | 肽和多肽药物的稳定类似物 |
| KR101292707B1 (ko) | 2004-02-23 | 2013-08-02 | 트러스티즈 오브 터프츠 칼리지 | 디펩티딜펩티다아제 ⅳ의 억제제 |
| US20060063719A1 (en) | 2004-09-21 | 2006-03-23 | Point Therapeutics, Inc. | Methods for treating diabetes |
-
2002
- 2002-11-26 EP EP10011373A patent/EP2316470A3/en not_active Withdrawn
- 2002-11-26 AU AU2002357767A patent/AU2002357767C1/en not_active Ceased
- 2002-11-26 JP JP2003547426A patent/JP4771661B2/ja not_active Expired - Fee Related
- 2002-11-26 EP EP02792306A patent/EP1469873A4/en not_active Withdrawn
- 2002-11-26 WO PCT/US2002/038053 patent/WO2003045977A2/en not_active Ceased
- 2002-11-26 CA CA002468192A patent/CA2468192A1/en not_active Abandoned
- 2002-11-26 US US10/496,706 patent/US7727964B2/en not_active Expired - Lifetime
- 2002-11-26 CA CA2837936A patent/CA2837936A1/en not_active Abandoned
-
2010
- 2010-06-01 US US12/791,517 patent/US20110082108A1/en not_active Abandoned
-
2011
- 2011-03-02 JP JP2011045147A patent/JP2011121989A/ja active Pending
-
2014
- 2014-02-24 JP JP2014033295A patent/JP2014139191A/ja not_active Abandoned
-
2016
- 2016-02-12 US US15/043,110 patent/US9757400B2/en not_active Expired - Fee Related
-
2017
- 2017-06-19 US US15/626,254 patent/US20170333461A1/en not_active Abandoned
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7674913B2 (en) | 2003-11-12 | 2010-03-09 | Phenomix Corporation | Heterocyclic boronic acid compounds |
| US7767828B2 (en) | 2003-11-12 | 2010-08-03 | Phenomix Corporation | Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| US7884217B2 (en) | 2003-11-12 | 2011-02-08 | Phenomix Corporation | Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| US7906658B2 (en) | 2003-11-12 | 2011-03-15 | Phenomix Corporation | Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV |
| US8415295B2 (en) | 2003-11-12 | 2013-04-09 | Phenomix Corporation | Heterocyclic boronic acid compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| US20170333461A1 (en) | 2017-11-23 |
| EP2316470A3 (en) | 2011-08-24 |
| WO2003045977A2 (en) | 2003-06-05 |
| WO2003045977A3 (en) | 2004-05-13 |
| US20160158260A1 (en) | 2016-06-09 |
| JP2011121989A (ja) | 2011-06-23 |
| JP2014139191A (ja) | 2014-07-31 |
| AU2002357767B2 (en) | 2008-12-04 |
| AU2002357767C1 (en) | 2009-03-19 |
| CA2837936A1 (en) | 2003-06-05 |
| EP2316470A2 (en) | 2011-05-04 |
| AU2002357767A1 (en) | 2003-06-10 |
| EP1469873A2 (en) | 2004-10-27 |
| US7727964B2 (en) | 2010-06-01 |
| JP4771661B2 (ja) | 2011-09-14 |
| EP1469873A4 (en) | 2007-10-03 |
| JP2005514377A (ja) | 2005-05-19 |
| US20110082108A1 (en) | 2011-04-07 |
| US9757400B2 (en) | 2017-09-12 |
| US20050070482A1 (en) | 2005-03-31 |
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