CA2465476A1 - Methods and compositions for correction of cardiac conduction disturbances - Google Patents

Methods and compositions for correction of cardiac conduction disturbances Download PDF

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Publication number
CA2465476A1
CA2465476A1 CA002465476A CA2465476A CA2465476A1 CA 2465476 A1 CA2465476 A1 CA 2465476A1 CA 002465476 A CA002465476 A CA 002465476A CA 2465476 A CA2465476 A CA 2465476A CA 2465476 A1 CA2465476 A1 CA 2465476A1
Authority
CA
Canada
Prior art keywords
cell
recombinant
connexin
cells
skeletal muscle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002465476A
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English (en)
French (fr)
Inventor
Randall J. Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2465476A1 publication Critical patent/CA2465476A1/en
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998Proteins not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
CA002465476A 2001-11-08 2002-11-07 Methods and compositions for correction of cardiac conduction disturbances Abandoned CA2465476A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33735201P 2001-11-08 2001-11-08
US60/337,352 2001-11-08
PCT/US2002/035932 WO2003039344A2 (en) 2001-11-08 2002-11-07 Methods and compositions for correction of cardiac conduction disturbances

Publications (1)

Publication Number Publication Date
CA2465476A1 true CA2465476A1 (en) 2003-05-15

Family

ID=23320214

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002465476A Abandoned CA2465476A1 (en) 2001-11-08 2002-11-07 Methods and compositions for correction of cardiac conduction disturbances

Country Status (10)

Country Link
US (2) US7252819B2 (https=)
EP (1) EP1453382A4 (https=)
JP (1) JP2005527482A (https=)
CN (1) CN1612691A (https=)
AU (1) AU2002359371A1 (https=)
BR (1) BR0214018A (https=)
CA (1) CA2465476A1 (https=)
IL (1) IL161862A0 (https=)
MX (1) MXPA04004396A (https=)
WO (1) WO2003039344A2 (https=)

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US7794702B2 (en) * 2003-01-15 2010-09-14 The Trustees Of Columbia University In The City Of New York Mesenchymal stem cells as a vehicle for ion channel transfer in syncytial structures
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US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US20050277124A1 (en) * 2004-06-10 2005-12-15 White Steven M Cardiac conduction system cells and uses thereof
US20050283218A1 (en) * 2004-06-22 2005-12-22 Williams Michael S Implantable chamber for biological induction or enhancement of muscle contraction
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US20110256112A2 (en) * 2008-03-07 2011-10-20 The Trustees Of Columbia University In The City Of New York Compensating for Atrioventricular Block Using a Nucleic Acid Encoding a Sodium Channel or Gap Junction Protein
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AU2011293386B2 (en) 2010-08-24 2014-08-21 The Regents Of The University Of California Compositions and methods for cardiac therapy
WO2012048276A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
WO2013036708A2 (en) 2011-09-07 2013-03-14 The Regents Of The University Of California Compositions and methods for tissue repair with extracellular matrices
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US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
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Also Published As

Publication number Publication date
US7494644B2 (en) 2009-02-24
US20080019953A1 (en) 2008-01-24
MXPA04004396A (es) 2004-08-11
WO2003039344A2 (en) 2003-05-15
US7252819B2 (en) 2007-08-07
BR0214018A (pt) 2005-04-19
US20030104568A1 (en) 2003-06-05
CN1612691A (zh) 2005-05-04
AU2002359371A1 (en) 2003-05-19
EP1453382A4 (en) 2005-05-18
WO2003039344A3 (en) 2003-12-31
IL161862A0 (en) 2005-11-20
JP2005527482A (ja) 2005-09-15
EP1453382A2 (en) 2004-09-08

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Legal Events

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EEER Examination request
FZDE Discontinued