CA2462881A1 - Compositions de valdecoxib a desintegration intra-orale preparees a l'aide d'un procede de sechage par pulverisation - Google Patents

Compositions de valdecoxib a desintegration intra-orale preparees a l'aide d'un procede de sechage par pulverisation Download PDF

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Publication number
CA2462881A1
CA2462881A1 CA002462881A CA2462881A CA2462881A1 CA 2462881 A1 CA2462881 A1 CA 2462881A1 CA 002462881 A CA002462881 A CA 002462881A CA 2462881 A CA2462881 A CA 2462881A CA 2462881 A1 CA2462881 A1 CA 2462881A1
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CA
Canada
Prior art keywords
composition
saccharide
valdecoxib
pharmaceutically acceptable
moldability
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002462881A
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English (en)
Inventor
Joseph P. Reo
Uday J. Shah
Ken Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia LLC
Original Assignee
Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2462881A1 publication Critical patent/CA2462881A1/fr
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Public Health (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Organic Chemistry (AREA)
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  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pregnancy & Childbirth (AREA)
  • Psychiatry (AREA)

Abstract

L'invention concerne des comprimés de valdecoxib à fusion rapide se désintégrant oralement et des procédés de préparation de ces formes de dosage. Ces compositions sont utilisées dans le traitement et la prophylaxie de troubles et d'états induits par la cyclooxygénase-2.
CA002462881A 2001-10-10 2002-10-10 Compositions de valdecoxib a desintegration intra-orale preparees a l'aide d'un procede de sechage par pulverisation Abandoned CA2462881A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32808801P 2001-10-10 2001-10-10
US60/328,088 2001-10-10
PCT/US2002/032333 WO2003030876A1 (fr) 2001-10-10 2002-10-10 Compositions de valdecoxib a desintegration intra-orale preparees a l'aide d'un procede de sechage par pulverisation

Publications (1)

Publication Number Publication Date
CA2462881A1 true CA2462881A1 (fr) 2003-04-17

Family

ID=23279455

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002462881A Abandoned CA2462881A1 (fr) 2001-10-10 2002-10-10 Compositions de valdecoxib a desintegration intra-orale preparees a l'aide d'un procede de sechage par pulverisation

Country Status (28)

Country Link
EP (1) EP1450769A1 (fr)
JP (1) JP2005508348A (fr)
KR (1) KR20050035138A (fr)
CN (1) CN1602187A (fr)
AP (1) AP2004003022A0 (fr)
BG (1) BG108675A (fr)
BR (1) BR0213152A (fr)
CA (1) CA2462881A1 (fr)
CO (1) CO5570687A2 (fr)
CZ (1) CZ2004456A3 (fr)
EA (1) EA200400423A1 (fr)
EC (1) ECSP045056A (fr)
GE (1) GEP20063857B (fr)
HR (1) HRP20040331A2 (fr)
HU (1) HUP0401776A2 (fr)
IL (1) IL161253A0 (fr)
IS (1) IS7211A (fr)
MA (1) MA27543A1 (fr)
MX (1) MXPA04003404A (fr)
NO (1) NO20041894L (fr)
NZ (1) NZ532184A (fr)
OA (1) OA12666A (fr)
PL (1) PL370136A1 (fr)
SK (1) SK1662004A3 (fr)
TN (1) TNSN04056A1 (fr)
WO (1) WO2003030876A1 (fr)
YU (1) YU37104A (fr)
ZA (1) ZA200402728B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7815937B2 (en) 1998-10-27 2010-10-19 Biovail Laboratories International Srl Quick dissolve compositions and tablets based thereon
WO2012087113A1 (fr) * 2010-12-24 2012-06-28 N.V. Nutricia Comprimé nutritionnel amélioré

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5576014A (en) * 1994-01-31 1996-11-19 Yamanouchi Pharmaceutical Co., Ltd Intrabuccally dissolving compressed moldings and production process thereof
CN1140267C (zh) * 1996-05-17 2004-03-03 麦克公司 治疗环加氧酶-2介导的疾病的每天一次的组合物
JP2003516353A (ja) * 1999-12-08 2003-05-13 ファルマシア コーポレイション ヴァルデコキシブ組成物
US6316029B1 (en) * 2000-05-18 2001-11-13 Flak Pharma International, Ltd. Rapidly disintegrating solid oral dosage form
DK1309315T3 (da) * 2000-08-18 2006-10-09 Pharmacia Corp Hurtigt disintegrerende oral valdecoxib-formulering
CN1638739A (zh) * 2000-08-18 2005-07-13 法玛西雅厄普约翰美国公司 治疗成瘾性障碍的化合物

Also Published As

Publication number Publication date
NZ532184A (en) 2005-12-23
EP1450769A1 (fr) 2004-09-01
AP2004003022A0 (en) 2004-06-30
ZA200402728B (en) 2005-03-17
TNSN04056A1 (fr) 2006-06-01
MXPA04003404A (es) 2004-06-18
BG108675A (en) 2005-03-31
YU37104A (sh) 2006-08-17
MA27543A1 (fr) 2005-10-03
PL370136A1 (en) 2005-05-16
CO5570687A2 (es) 2005-10-31
SK1662004A3 (sk) 2005-07-01
OA12666A (en) 2006-06-19
IL161253A0 (en) 2004-09-27
BR0213152A (pt) 2004-10-19
CN1602187A (zh) 2005-03-30
EA200400423A1 (ru) 2004-10-28
JP2005508348A (ja) 2005-03-31
KR20050035138A (ko) 2005-04-15
CZ2004456A3 (cs) 2005-03-16
HUP0401776A2 (hu) 2004-12-28
WO2003030876A1 (fr) 2003-04-17
GEP20063857B (en) 2006-06-26
IS7211A (is) 2004-04-07
HRP20040331A2 (en) 2005-12-31
ECSP045056A (es) 2004-08-27
NO20041894D0 (no) 2004-05-07
NO20041894L (no) 2004-07-07

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