CA2458394C - Lipophilic drug compositions - Google Patents

Lipophilic drug compositions Download PDF

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Publication number
CA2458394C
CA2458394C CA2458394A CA2458394A CA2458394C CA 2458394 C CA2458394 C CA 2458394C CA 2458394 A CA2458394 A CA 2458394A CA 2458394 A CA2458394 A CA 2458394A CA 2458394 C CA2458394 C CA 2458394C
Authority
CA
Canada
Prior art keywords
lipid
molecule
drug
biologically active
encapsulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2458394A
Other languages
English (en)
French (fr)
Other versions
CA2458394A1 (en
Inventor
Michael T. Sung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2458394A1 publication Critical patent/CA2458394A1/en
Application granted granted Critical
Publication of CA2458394C publication Critical patent/CA2458394C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2458394A 2001-08-23 2002-08-21 Lipophilic drug compositions Expired - Fee Related CA2458394C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US31409201P 2001-08-23 2001-08-23
US60/314,092 2001-08-23
US10/134,329 2002-04-29
US10/134,329 US7125568B2 (en) 2001-08-23 2002-04-29 Lipophilic drug compositions
PCT/US2002/026571 WO2003018064A2 (en) 2001-08-23 2002-08-21 Lipophilic drug compositions

Publications (2)

Publication Number Publication Date
CA2458394A1 CA2458394A1 (en) 2003-03-06
CA2458394C true CA2458394C (en) 2013-04-23

Family

ID=26832219

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2458394A Expired - Fee Related CA2458394C (en) 2001-08-23 2002-08-21 Lipophilic drug compositions

Country Status (6)

Country Link
US (2) US7125568B2 (enExample)
EP (1) EP1420828B1 (enExample)
CA (1) CA2458394C (enExample)
ES (1) ES2395408T3 (enExample)
TW (1) TWI302459B (enExample)
WO (1) WO2003018064A2 (enExample)

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AU2006235490A1 (en) * 2005-04-12 2006-10-19 Romark Laboratories, L.C. Methods for treating diseases through the function of molecular chaperones such as protein disulfide isomerases, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents
EA015560B1 (ru) 2006-01-09 2011-08-30 Ромарк Лэборетериз, Эл.Си. Способ лечения вирусного гепатита
WO2007134245A2 (en) * 2006-05-12 2007-11-22 Wisconsin Alumni Research Foundation Elastin-like polymer delivery vehicles
US20100104625A1 (en) * 2007-02-16 2010-04-29 Cornell University Biodegradable compositions and materials
US8354116B2 (en) * 2007-06-18 2013-01-15 Biochemics, Inc. Bifunctional synthetic molecules
US7790401B2 (en) * 2007-08-06 2010-09-07 Siemens Healthcare Diagnostics Methods for detection of immunosuppressant drugs
TW200936180A (en) * 2007-11-27 2009-09-01 Intervet Int Bv Carrier particle for a microorganism or subunit thereof, pharmaceutical composition comprising such particles, method for preparation of this composition and its use in the treatment of animals
GB0724550D0 (en) * 2007-12-18 2008-01-30 Univ Hull Formulations
GB0812513D0 (en) * 2008-07-09 2008-08-13 Univ Hull Delivery vehicle
WO2011044136A1 (en) * 2009-10-05 2011-04-14 Catabasis Pharmaceuticals, Inc. Fatty acid acipimox derivatives and their uses
CA2811931C (en) 2010-10-20 2015-06-16 Galderma S.A. Method of treating herpes virus infection using macrocyclic lactone compound
WO2015069699A1 (en) * 2013-11-05 2015-05-14 Ultragenyx Pharmaceutical Inc. Creatine analogs and the use thereof
EP3475442B1 (en) 2016-06-23 2024-10-23 The Regents of The University of Michigan 12(s)-hydroxyeicosatrienoic acid compounds and their use as therapeutic agents
CN111417620B (zh) 2017-12-01 2023-08-25 奥特吉尼克斯制药公司 肌酸前药、其组合物以及使用方法

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DE2655369A1 (de) * 1976-12-03 1978-06-08 Schering Ag 5-(subst. phenyl)-oxazolidinone und deren schwefelanaloga sowie verfahren zu deren herstellung
US4315018A (en) * 1978-12-07 1982-02-09 Rossignol Jean F Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
US5340587A (en) * 1985-05-22 1994-08-23 Liposome Technology, Inc. Liposome/bronchodilator method & System
ATE78158T1 (de) * 1985-05-22 1992-08-15 Liposome Technology Inc Verfahren und system zum einatmen von liposomen.
JPH0751496B2 (ja) * 1986-04-02 1995-06-05 武田薬品工業株式会社 リポソ−ムの製造法
MX9203808A (es) * 1987-03-05 1992-07-01 Liposome Co Inc Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos.
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MX9604483A (es) * 1994-09-08 1998-02-28 Jean-Francois Rossignol Derivados de benzamida, composiciones que contienen dicho derivado y uso de las mismas.
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Also Published As

Publication number Publication date
WO2003018064A3 (en) 2003-09-25
WO2003018064A2 (en) 2003-03-06
ES2395408T3 (es) 2013-02-12
TWI302459B (enExample) 2008-11-01
EP1420828B1 (en) 2012-09-26
EP1420828A2 (en) 2004-05-26
US20030108596A1 (en) 2003-06-12
CA2458394A1 (en) 2003-03-06
US7390506B2 (en) 2008-06-24
US20060147525A1 (en) 2006-07-06
US7125568B2 (en) 2006-10-24

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MKLA Lapsed

Effective date: 20150821