CA2456626A1 - Microstructures destinees a distribuer une composition par voie cutanee dans la peau au moyen de structures rotatives - Google Patents

Microstructures destinees a distribuer une composition par voie cutanee dans la peau au moyen de structures rotatives Download PDF

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Publication number
CA2456626A1
CA2456626A1 CA002456626A CA2456626A CA2456626A1 CA 2456626 A1 CA2456626 A1 CA 2456626A1 CA 002456626 A CA002456626 A CA 002456626A CA 2456626 A CA2456626 A CA 2456626A CA 2456626 A1 CA2456626 A1 CA 2456626A1
Authority
CA
Canada
Prior art keywords
skin
microelements
composition
stratum corneum
microstructures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002456626A
Other languages
English (en)
Other versions
CA2456626C (fr
Inventor
Vladimir Gartstein
Faiz Feisal Sherman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corium Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/952,391 external-priority patent/US7108681B2/en
Priority claimed from US10/216,148 external-priority patent/US20040087992A1/en
Application filed by Individual filed Critical Individual
Publication of CA2456626A1 publication Critical patent/CA2456626A1/fr
Application granted granted Critical
Publication of CA2456626C publication Critical patent/CA2456626C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/322—Skin grafting apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A61B2017/00761—Removing layer of skin tissue, e.g. wrinkles, scars or cancerous tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A61B2017/00765—Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B2017/320004—Surgical cutting instruments abrasive
    • A61B2017/320008—Scrapers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Transplantation (AREA)
  • Medicinal Preparation (AREA)
  • Surgical Instruments (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
CA002456626A 2001-09-14 2002-09-13 Microstructures destinees a distribuer une composition par voie cutanee dans la peau au moyen de structures rotatives Expired - Lifetime CA2456626C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/952,391 US7108681B2 (en) 2000-10-16 2001-09-14 Microstructures for delivering a composition cutaneously to skin
US09/952,391 2001-09-14
US10/216,148 US20040087992A1 (en) 2002-08-09 2002-08-09 Microstructures for delivering a composition cutaneously to skin using rotatable structures
US10/216,148 2002-08-09
PCT/US2002/029228 WO2003024518A2 (fr) 2001-09-14 2002-09-13 Microstructures destinees a distribuer une composition par voie cutanee dans la peau au moyen de structures rotatives

Publications (2)

Publication Number Publication Date
CA2456626A1 true CA2456626A1 (fr) 2003-03-27
CA2456626C CA2456626C (fr) 2009-01-20

Family

ID=26910709

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002456626A Expired - Lifetime CA2456626C (fr) 2001-09-14 2002-09-13 Microstructures destinees a distribuer une composition par voie cutanee dans la peau au moyen de structures rotatives

Country Status (5)

Country Link
EP (1) EP1425064A2 (fr)
JP (1) JP2005503210A (fr)
AU (1) AU2002333636A1 (fr)
CA (1) CA2456626C (fr)
WO (1) WO2003024518A2 (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7108681B2 (en) 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US6663820B2 (en) 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
IL152912A0 (en) * 2002-11-18 2003-06-24 Nanopass Ltd Micro needle systems
US7888546B2 (en) 2003-07-03 2011-02-15 Corium International, Inc. Wound dressing, ingredient delivery device and IV hold-down, and method relating to same
EP1740256A4 (fr) 2003-11-10 2011-06-29 Agency Science Tech & Res Micro-aiguilles et fabrication de micro-aiguilles
JP2005246595A (ja) * 2004-03-05 2005-09-15 Ritsumeikan マイクロニードルアレイ及びその製造方法
CA2562643A1 (fr) * 2004-04-12 2005-11-24 Allergan, Inc. Systeme d'injection multi-sites
ES2346069T3 (es) * 2004-04-30 2010-10-08 Gyung Su Cho Dispositivo electrico de dermoabrasion.
US20070078414A1 (en) 2005-08-05 2007-04-05 Mcallister Devin V Methods and devices for delivering agents across biological barriers
JP5066566B2 (ja) 2006-07-03 2012-11-07 ホナム ペトロケミカル コープ マイクロニードルローラアセンブリ
JP4821993B2 (ja) * 2006-07-21 2011-11-24 芳一 飛永 マイクロインプリメント及びその製造方法
KR200451185Y1 (ko) 2007-02-15 2010-12-01 (주)클리니칼레졸루션아시아 모듈식 마이크로니들 롤러
GB2448493B (en) * 2007-04-16 2009-10-14 Dewan Fazlul Hoque Chowdhury Microneedle transdermal delivery device
EP2664323B1 (fr) 2007-04-16 2020-07-29 Corium, Inc. Actif comprenant des réseaux de micro-aiguilles coulés en solution
WO2009048607A1 (fr) 2007-10-10 2009-04-16 Corium International, Inc. Distribution de vaccin par l'intermédiaire de réseaux de micro-aiguilles
US20100292723A1 (en) * 2007-12-07 2010-11-18 Myeong In Lee Disk needle roller
WO2009130926A1 (fr) * 2008-04-22 2009-10-29 南部化成株式会社 Procédé endermique, organisateur d'aiguille et dispositif d'injecteur endermique
WO2009144624A1 (fr) * 2008-05-28 2009-12-03 Koninklijke Philips Electronics N.V. Dispositif d'apport de médicament commandé
JP5357257B2 (ja) * 2008-09-03 2013-12-04 ディーティーエスラッブ カンパニー リミテッド 皮膚刺激器
US20110144591A1 (en) * 2009-12-11 2011-06-16 Ross Russell F Transdermal Delivery Device
ES2719595T3 (es) 2010-05-04 2019-07-11 Corium Int Inc Método y dispositivo para la administración transdérmica de la hormona paratiroidea usando una matriz de microproyección
GB201107642D0 (en) 2011-05-09 2011-06-22 Univ Cork Method
JP6182137B2 (ja) * 2012-06-12 2017-08-16 久光製薬株式会社 マイクロニードル・シート
EP2928395B1 (fr) * 2012-12-06 2022-02-02 SRGI Holdings LLC Dispositifs médicaux à réseau de pixels
EP2934660B1 (fr) 2012-12-21 2019-07-17 Corium, Inc. Micro-réseau pour la distribution d'un agent thérapeutique et son procédé de fabrication
CA2903748C (fr) 2013-03-12 2021-11-02 Corium International, Inc. Applicateurs de microprojection
WO2014150285A2 (fr) 2013-03-15 2014-09-25 Corium International, Inc. Applicateurs de microprojection d'impacts multiples et procédés d'utilisation
CN105246458B (zh) 2013-03-15 2020-09-15 考里安公司 用于治疗剂递送的微阵列及其使用方法
AU2014237279B2 (en) 2013-03-15 2018-11-22 Corium Pharma Solutions, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
JP2016512754A (ja) 2013-03-15 2016-05-09 コリウム インターナショナル， インコーポレイテッド 治療剤の送達のためのマイクロアレイ、使用方法および製造方法
US9849272B2 (en) 2013-06-18 2017-12-26 Hisamitsu Pharmaceutical Co., Inc. Applicator
US10039911B2 (en) 2013-06-19 2018-08-07 Hisamitsu Pharmaceutical Co., Inc. Applicator
US9694142B2 (en) 2013-09-03 2017-07-04 Visage Sculpture, PLLC Device for percutaneous delivery of therapeutic agents, and a method for its use
JP6272333B2 (ja) 2013-09-06 2018-01-31 久光製薬株式会社 マイクロニードル・シート
US20170049695A1 (en) 2014-02-27 2017-02-23 Hisamitsu Pharmaceutical Co., Inc. Microneedle sheet
WO2016036866A1 (fr) 2014-09-04 2016-03-10 Corium International, Inc. Matrice de microstructures, procédé de production et procédés d'utilisation
JP6571680B2 (ja) 2014-12-05 2019-09-04 久光製薬株式会社 マイクロニードルデバイスシステム
US10004887B2 (en) * 2015-02-18 2018-06-26 Alma Therapeutics Ltd. Transdermal delivery assembly
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
WO2017104491A1 (fr) 2015-12-15 2017-06-22 久光製薬株式会社 Feuille à micro-aiguilles
US11007358B2 (en) 2016-09-01 2021-05-18 Hisamitsu Pharmaceutical Co., Inc. Microneedle sheet
KR101906336B1 (ko) * 2018-03-22 2018-10-10 한국바이오기술공사(주) 펌프 내장형 니들 디스크 롤러 장치
CN109925590B (zh) * 2019-03-28 2021-10-08 吴晓苏 一种耦合剂快速刷涂及擦拭装置

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4637758Y1 (fr) * 1967-12-13 1971-12-27
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
DE2319591C2 (de) * 1973-04-18 1982-02-25 Kirchner & Wilhelm, 7000 Stuttgart Medizinischer Apparat
FR2232331B1 (fr) * 1973-06-06 1978-03-24 Guerin A Ets
FR2535602B1 (fr) * 1982-11-05 1986-06-13 Stallergenes Lab Dispositif scarificateur
US4583982A (en) * 1984-08-24 1986-04-22 Vlock D G Fluid dispenser
CA2016900A1 (fr) * 1989-07-06 1991-01-06 Ronald J. Filipski Applicateur clinique en forme de fourchette
JP2646766B2 (ja) * 1989-11-08 1997-08-27 日本電気株式会社 皮膚角層の除去器具
JP3189337B2 (ja) * 1991-11-08 2001-07-16 日本電気株式会社 皮膚角層の除去器具および除去方法
JP2551742B2 (ja) * 1994-05-23 1996-11-06 三星電機株式会社 医薬品投与用皮膚傷形成装置
CA2149836C (fr) * 1994-05-23 1999-07-06 Sang Bae Choi Dispositif perforant pour administration transdermique
CA2205444A1 (fr) * 1994-12-09 1996-06-13 Novartis Ag Systeme transdermique
US5948488A (en) * 1996-04-30 1999-09-07 3M Innovative Properties Company Glittering cube-corner article
US6183434B1 (en) * 1996-07-03 2001-02-06 Spectrx, Inc. Multiple mechanical microporation of skin or mucosa
JP3097600B2 (ja) * 1997-05-30 2000-10-10 日本電気株式会社 角質層穿刺装置
US5938684A (en) * 1997-12-09 1999-08-17 Sierra Self Healing Products, Inc. Accupressure device for therapeutic relief
KR100572539B1 (ko) * 1997-12-11 2006-04-24 알자 코포레이션 경피성 작용제 유동률을 증진시키기 위한 장치
DE69921489T2 (de) * 1998-08-31 2005-10-27 Johnson & Johnson Consumer Companies, Inc. Elektrotransportvorrichtung mit klingen
CA2352974A1 (fr) * 1998-12-18 2000-06-22 John H. Livingston Ensembles d'injection pourvus d'elements de micro-perforation, utilises avec des dispositifs medicaux, et leurs procedes d'utilisation
GB0017999D0 (en) * 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
US7108681B2 (en) * 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin

Also Published As

Publication number Publication date
AU2002333636A1 (en) 2003-04-01
WO2003024518A2 (fr) 2003-03-27
JP2005503210A (ja) 2005-02-03
WO2003024518A3 (fr) 2003-09-25
EP1425064A2 (fr) 2004-06-09
CA2456626C (fr) 2009-01-20

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Effective date: 20220913