CA2454181A1 - Use of corticotroph-derived glycoprotein hormone to induce lipolysis - Google Patents

Use of corticotroph-derived glycoprotein hormone to induce lipolysis Download PDF

Info

Publication number
CA2454181A1
CA2454181A1 CA002454181A CA2454181A CA2454181A1 CA 2454181 A1 CA2454181 A1 CA 2454181A1 CA 002454181 A CA002454181 A CA 002454181A CA 2454181 A CA2454181 A CA 2454181A CA 2454181 A1 CA2454181 A1 CA 2454181A1
Authority
CA
Canada
Prior art keywords
cgh
ual
cys
ala
thr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002454181A
Other languages
English (en)
French (fr)
Inventor
James D. Kelly
Philippa J. Webster
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2454181A1 publication Critical patent/CA2454181A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/24Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Reproductive Health (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002454181A 2001-07-13 2002-07-15 Use of corticotroph-derived glycoprotein hormone to induce lipolysis Abandoned CA2454181A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30528401P 2001-07-13 2001-07-13
US60/305,284 2001-07-13
PCT/US2002/022747 WO2003006051A1 (en) 2001-07-13 2002-07-15 Use of corticotroph-derived glycoprotein hormone to induce lipolysis

Publications (1)

Publication Number Publication Date
CA2454181A1 true CA2454181A1 (en) 2003-01-23

Family

ID=23180168

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002454181A Abandoned CA2454181A1 (en) 2001-07-13 2002-07-15 Use of corticotroph-derived glycoprotein hormone to induce lipolysis

Country Status (7)

Country Link
US (2) US20030095983A1 (https=)
EP (1) EP1414485A1 (https=)
JP (1) JP2004521952A (https=)
CA (1) CA2454181A1 (https=)
IL (1) IL159526A0 (https=)
WO (1) WO2003006051A1 (https=)
ZA (1) ZA200400060B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030059877A1 (en) * 2000-01-18 2003-03-27 Sietse Mosselman Human cystine knot polypeptide
CA2487924A1 (en) * 2002-06-10 2003-12-18 Zymogenetics, Inc. Use of corticotroph-derived glycoprotein hormone to treat inflammation and potentiate glucocorticoid action
JP2007513191A (ja) * 2003-12-05 2007-05-24 ザイモジェネティクス,インコーポレイティド 甲状腺刺激ホルモンを用いての炎症の処理方法
CA2555908A1 (en) * 2004-03-05 2005-09-22 Zymogenetics, Inc. Use of corticotroph-derived glycoprotein hormone to treat liver steatosis
JP5118292B2 (ja) * 2005-06-16 2013-01-16 株式会社ロッテ 脂肪分解促進剤
US20070014736A1 (en) * 2005-06-29 2007-01-18 Okada Shannon L Methods of delivering corticotroph-derived glycoprotein hormone
DK1971361T3 (da) 2005-12-23 2014-09-08 James D Kelly Forbedrede glycoformer af thyroidstimulerende hormonreceptor-polypeptidagonist til behandling af metabolisk syndrom

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE336577T1 (de) * 1998-02-13 2006-09-15 Zymogenetics Inc Protein, welches durch einen cystinknoten charakterisiert ist und verfahren zu dessen herstellung
WO2000078964A1 (en) * 1999-06-17 2000-12-28 Amgen Inc. Glycoprotein hormone family member
US20020068279A1 (en) * 1999-12-06 2002-06-06 Curagen Corporation Novel Proteins and nucleic acids encoding the same
US7514239B2 (en) * 2000-03-28 2009-04-07 Amgen Inc. Nucleic acid molecules encoding beta-like glycoprotein hormone polypeptides and heterodimers thereof
US20040005554A1 (en) * 2000-05-08 2004-01-08 Tayar Nabil El Novel glycoproteins and methods of use thereof

Also Published As

Publication number Publication date
JP2004521952A (ja) 2004-07-22
ZA200400060B (en) 2004-08-17
WO2003006051A1 (en) 2003-01-23
US20060035818A1 (en) 2006-02-16
US20030095983A1 (en) 2003-05-22
EP1414485A1 (en) 2004-05-06
IL159526A0 (en) 2004-06-01

Similar Documents

Publication Publication Date Title
RU2593960C2 (ru) Фармацевтическая композиция для лечения метаболического синдрома
RU2207871C2 (ru) Способ лечения ожирения
JP2000511561A (ja) 肥満症の処置のためのcntf(毛様体神経成長因子)受容体アクティベーターの使用
JP2014520868A (ja) メタボリックシンドロームを処置するための医薬組成物
CZ294848B6 (cs) Glukagonu podobný peptid-1 zlepšuje odpověď ß-buněk na glukózu u subjektů se zhoršenou tolerancí glukózy
TW200843794A (en) Use of long-acting GLP-1 receptor agonists to improve insulin sensitivity and lipid profiles
SK142001A3 (en) Neurotrophic growth factor
PL211763B1 (pl) Zastosowanie osteopontyny, cząsteczki kwasu nukleinowego, komórki zmodyfikowanej genetycznie oraz kompozycja farmaceutyczna
TW200808324A (en) Method for shortening hospital stay in patients with congestive heart failure and acute fluid overload
CA3053267A1 (en) Compositions and methods for recombinant nerve growth factor
WO2005099741A1 (ja) 運動ニューロン疾患治療薬
CA2454181A1 (en) Use of corticotroph-derived glycoprotein hormone to induce lipolysis
US20040176294A1 (en) Use of thyroid-stimulating hormone to induce lipolysis
Dardevet et al. Leucine: a key amino acid in ageing-associated sarcopenia?
US9333241B2 (en) Thyroid-stimulating hormone receptor polypeptide agonist glycoforms to treat metabolic syndrome
EP1172113A1 (en) Remedies for autonomic neuropathy
AU2002318259A1 (en) Use of corticotroph-derived glycoprotein hormone to induce lipolysis
Wilber Neuropeptides, appetite regulation, and human obesity
US20220118052A1 (en) Materials and methods for modulating glucose uptake
EP2026831A2 (en) Methods and compositions for treating and preventing peripheral nerve damage
Hernandez et al. Pupillary effects of neurotensin: structure-activity relationships
WO2025090589A1 (en) Furostan-3-ol derivatives for the treatment of obesity and diabetes
CALZA et al. flammation and in myelin repair, centering upon the possible role of NGF in
AU2005286474A1 (en) Use of IL-17F for the treatment and/or prevention of neurologic diseases
WO2021210684A1 (ja) 運動亢進症治療剤

Legal Events

Date Code Title Description
FZDE Discontinued