CA2449409C - Derives de quinacridone utilises comme reactifs de marquage pour la detection par fluorescence de matieres vivantes - Google Patents

Derives de quinacridone utilises comme reactifs de marquage pour la detection par fluorescence de matieres vivantes Download PDF

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Publication number
CA2449409C
CA2449409C CA2449409A CA2449409A CA2449409C CA 2449409 C CA2449409 C CA 2449409C CA 2449409 A CA2449409 A CA 2449409A CA 2449409 A CA2449409 A CA 2449409A CA 2449409 C CA2449409 C CA 2449409C
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Expired - Fee Related
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CA2449409A
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English (en)
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CA2449409A1 (fr
Inventor
John Anthony Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SPT Labtech Ltd
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GE Healthcare UK Ltd
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Publication of CA2449409A1 publication Critical patent/CA2449409A1/fr
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Publication of CA2449409C publication Critical patent/CA2449409C/fr
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    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B48/00—Quinacridones
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B15/00—Acridine dyes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
CA2449409A 2001-06-04 2002-05-30 Derives de quinacridone utilises comme reactifs de marquage pour la detection par fluorescence de matieres vivantes Expired - Fee Related CA2449409C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0113434.5A GB0113434D0 (en) 2001-06-04 2001-06-04 Quinacridone derivatives as labels for fluorescence detection of biological materials
GB0113434.5 2001-06-04
PCT/GB2002/002537 WO2002099432A2 (fr) 2001-06-04 2002-05-30 Derives de quinacridone utilises comme reactifs de marquage pour la detection par fluorescence de matieres vivantes

Publications (2)

Publication Number Publication Date
CA2449409A1 CA2449409A1 (fr) 2002-12-12
CA2449409C true CA2449409C (fr) 2012-07-17

Family

ID=9915774

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2449409A Expired - Fee Related CA2449409C (fr) 2001-06-04 2002-05-30 Derives de quinacridone utilises comme reactifs de marquage pour la detection par fluorescence de matieres vivantes

Country Status (9)

Country Link
US (1) US7335771B2 (fr)
EP (1) EP1399742B1 (fr)
JP (1) JP4317444B2 (fr)
AT (1) ATE502301T1 (fr)
AU (1) AU2002314302B2 (fr)
CA (1) CA2449409C (fr)
DE (1) DE60239458D1 (fr)
GB (2) GB0113434D0 (fr)
WO (1) WO2002099432A2 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2398123B (en) * 2002-04-19 2005-03-02 Amersham Biosciences Uk Ltd Methods for measuring enzyme activity
GB0208989D0 (en) 2002-04-19 2002-05-29 Amersham Biosciences Uk Ltd Methods for measuring enzyme activity
GB0217562D0 (en) * 2002-07-30 2002-09-11 Amersham Biosciences Uk Ltd Site-specific labelling of proteins using acridone and quinacridone lifetime dyes
GB0317743D0 (en) * 2003-07-30 2003-09-03 Amersham Biosciences Uk Ltd Method for measuring aromatase activity
KR20070043810A (ko) * 2004-06-29 2007-04-25 시바 스페셜티 케미칼스 홀딩 인크. 형광 퀴나크리돈
GB0421693D0 (en) 2004-09-30 2004-11-03 Amersham Biosciences Uk Ltd Method for measuring binding of a test compound to a G-protein coupled receptor
GB0505777D0 (en) * 2005-03-22 2005-04-27 Amersham Biosciences Uk Ltd Enzyme detection method and reagent
EP1790695B1 (fr) 2005-11-28 2009-02-18 Agfa Graphics N.V. Dispersions de quinacridone non-aqueuses par utilisation de synergistes de dispersion
US20090186200A1 (en) * 2006-05-22 2009-07-23 Brian Thompson 2,5-di(methoxyanilino) terephthalic acid polymorphs and quinacridones realized therefrom
WO2008030120A1 (fr) * 2006-09-07 2008-03-13 Auckland Uniservices Limited Procédé pour la détection par fluorescence d'une activité nitroréductase à l'aide de composés aromatiques à substitution nitro
EP2268656A1 (fr) * 2008-03-14 2011-01-05 Assaymetrics Limited Peptides fluorogènes et leur procédé de production
EP2316890A1 (fr) * 2009-11-03 2011-05-04 Agfa-Gevaert Préparation et dispersion de pigments colorés modifiés à la surface
CA2746891A1 (fr) * 2010-07-19 2012-01-19 Universite De Montreal Marqueurs fluorescents et leur utilisation pour le marquage de proteines cibles specifiques
JP2014508537A (ja) 2011-03-25 2014-04-10 アルマック・サイエンシーズ・（スコットランド）・リミテッド 酵素アッセイ
CN102276600B (zh) * 2011-04-22 2012-11-14 华东理工大学 喹吖啶酮衍生物及其用途
GB2511110A (en) * 2013-02-25 2014-08-27 Sudarshan Chemical Ind Ltd Pigments
US20160289728A1 (en) * 2013-11-21 2016-10-06 The University Of Tokyo Method for detecting fluorescence or absorbance, method for suppressing background, method for measuring adp, method for measuring activity of adp-synthesizing enzyme, and method for measuring activity of glucosyltransferase
US9701667B2 (en) 2014-05-05 2017-07-11 University Of Ottawa Coumarin-based fluorogenic agents and uses thereof for specific protein labelling
US10591485B2 (en) 2015-01-23 2020-03-17 University Of Ottawa Peptide tags for fluorescent labelling of proteins
JP2017020896A (ja) * 2015-07-10 2017-01-26 国立大学法人北陸先端科学技術大学院大学 Ｎ末端標識剤、これを用いた蛍光標識タンパク質及びその製造方法
US9958452B2 (en) 2015-12-14 2018-05-01 University Of Ottawa Highly fluorogenic protein labelling agents
EP3246969B1 (fr) 2016-05-17 2018-12-12 Samsung SDI Co., Ltd. Séparateur pour batterie rechargeable et batterie rechargeable au lithium l'incluant
US11414387B2 (en) 2017-11-20 2022-08-16 Stingthera, Inc. Oxoacridinyl acetic acid derivatives and methods of use
EP3713920A4 (fr) 2017-11-20 2021-04-14 Silicon Swat, Inc. Dérivés d'acide oxoacridinyle acétique et procédés d'utilisation
CN112794813B (zh) * 2020-12-30 2022-04-26 四川大学华西医院 一种用于荧光标记的环丁烯衍生物
CN114605405B (zh) * 2022-03-09 2023-09-05 吉林大学 一种基于喹吖啶酮骨架的细胞脂滴荧光成像探针及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61168666A (ja) * 1985-01-21 1986-07-30 Dainippon Ink & Chem Inc 顔料組成物
EP0673979B1 (fr) * 1994-03-25 2000-08-30 Ciba SC Holding AG Colorants fluorescents ayant des groupes cyanimino
US5713999A (en) * 1996-04-29 1998-02-03 Bayer Corporation Incorporation of pigment derivatives in quinacridone processes
GB0208989D0 (en) * 2002-04-19 2002-05-29 Amersham Biosciences Uk Ltd Methods for measuring enzyme activity

Also Published As

Publication number Publication date
GB0113434D0 (en) 2001-07-25
CA2449409A1 (fr) 2002-12-12
GB0326464D0 (en) 2003-12-17
US7335771B2 (en) 2008-02-26
GB2391550B (en) 2005-02-02
EP1399742B1 (fr) 2011-03-16
EP1399742A2 (fr) 2004-03-24
US20040171014A1 (en) 2004-09-02
WO2002099432A3 (fr) 2003-05-01
DE60239458D1 (de) 2011-04-28
JP2005501228A (ja) 2005-01-13
ATE502301T1 (de) 2011-04-15
AU2002314302B2 (en) 2006-02-23
JP4317444B2 (ja) 2009-08-19
WO2002099432A2 (fr) 2002-12-12
GB2391550A (en) 2004-02-11

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