CA2446502C - High capacity assay platforms - Google Patents

High capacity assay platforms Download PDF

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Publication number
CA2446502C
CA2446502C CA2446502A CA2446502A CA2446502C CA 2446502 C CA2446502 C CA 2446502C CA 2446502 A CA2446502 A CA 2446502A CA 2446502 A CA2446502 A CA 2446502A CA 2446502 C CA2446502 C CA 2446502C
Authority
CA
Canada
Prior art keywords
polymer
binding ligand
polymer matrix
substrate
assay platform
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2446502A
Other languages
English (en)
French (fr)
Other versions
CA2446502A1 (en
Inventor
John Dapron
William Karl Kappel
Handong Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Sigma Aldrich Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Aldrich Co LLC filed Critical Sigma Aldrich Co LLC
Publication of CA2446502A1 publication Critical patent/CA2446502A1/en
Application granted granted Critical
Publication of CA2446502C publication Critical patent/CA2446502C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nanotechnology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2446502A 2001-05-14 2002-04-29 High capacity assay platforms Expired - Fee Related CA2446502C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/854,638 US6825032B2 (en) 2001-05-14 2001-05-14 High capacity assay platforms
US09/854,638 2001-05-14
PCT/US2002/013422 WO2002092834A2 (en) 2001-05-14 2002-04-29 High capacity assay platforms

Publications (2)

Publication Number Publication Date
CA2446502A1 CA2446502A1 (en) 2002-11-21
CA2446502C true CA2446502C (en) 2011-07-26

Family

ID=25319220

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2446502A Expired - Fee Related CA2446502C (en) 2001-05-14 2002-04-29 High capacity assay platforms

Country Status (5)

Country Link
US (4) US6825032B2 (https=)
EP (1) EP1421386A4 (https=)
JP (1) JP2005514583A (https=)
CA (1) CA2446502C (https=)
WO (1) WO2002092834A2 (https=)

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* Cited by examiner, † Cited by third party
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US7192560B2 (en) * 2001-12-20 2007-03-20 3M Innovative Properties Company Methods and devices for removal of organic molecules from biological mixtures using anion exchange
EP1656443A4 (en) * 2003-05-02 2007-06-06 Sigma Aldrich Co SOLID PHASE CELLYSIS AND IMPACT PLATFORM
US7557433B2 (en) * 2004-10-25 2009-07-07 Mccain Joseph H Microelectronic device with integrated energy source
US20050239112A1 (en) * 2004-04-01 2005-10-27 Migenix, Inc. Methods and processes for attaching compounds to matrices
WO2006026248A1 (en) 2004-08-25 2006-03-09 Sigma-Aldrich Co. Compositions and methods employing zwitterionic detergent combinations
US7344847B2 (en) * 2005-02-25 2008-03-18 The Regents Of The University Of Michigan Nanoscale patterning and immobilization of bio-molecules
US20070134685A1 (en) * 2005-09-06 2007-06-14 Invitrogen Corporation Control of chemical modification
WO2007049269A1 (en) * 2005-10-27 2007-05-03 Bio-Rad Haifa Ltd. Binding layer and method for its preparation and uses thereof
US7923054B2 (en) * 2006-04-19 2011-04-12 Gore Enterprise Holdings, Inc. Functional porous substrates for attaching biomolecules
US20100129878A1 (en) * 2007-04-25 2010-05-27 Parthasarathy Ranjani V Methods for nucleic acid amplification
WO2008134472A1 (en) * 2007-04-25 2008-11-06 3M Innovative Properties Company Compositions, methods, and devices for isolating biological materials
US20080268440A1 (en) * 2007-04-26 2008-10-30 Liu Timothy Z Biomolecule immobilization on surface via hydrophobic interactions
JP5916256B2 (ja) 2011-05-05 2016-05-11 コーニング インコーポレイテッド 細胞培養のための合成組成物および被覆
TWI461530B (zh) * 2013-05-16 2014-11-21 中原大學 分子固定方法及其系統

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DE2902959C2 (de) * 1979-01-26 1984-11-29 Battelle-Institut E.V., 6000 Frankfurt Verfahren zur Oberflächenmodifizierung von Kunststoffen, Azido- bzw. Diazoderivate und deren Herstellung
SE8103137L (sv) * 1981-05-19 1982-11-20 Pharmacia Ab Polymer med kvartera aminogrupper
US5512329A (en) * 1982-09-29 1996-04-30 Bsi Corporation Substrate surface preparation
US5002582A (en) * 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
US5336762A (en) 1985-11-18 1994-08-09 Access Pharmaceuticals, Inc. Polychelating agents for image and spectral enhancement (and spectral shift)
US5047513A (en) 1986-07-10 1991-09-10 Hoffmann-La Roche Inc. Metal chelate resins
US4886836A (en) * 1987-06-03 1989-12-12 Pall Corporation Activated medium with low non-specific protein adsorption
SE462454B (sv) 1988-11-10 1990-06-25 Pharmacia Ab Maetyta foer anvaendning i biosensorer
WO1992003732A2 (en) 1990-08-28 1992-03-05 Bioprobe International, Inc. Compositions and methods for enhanced binding in biological assays
US6022966A (en) * 1993-11-22 2000-02-08 Neorx Corporation Pretargeting methods and compounds
AU6393994A (en) 1993-02-19 1994-09-14 Arris Pharmaceutical Corporation Thin film hpmp matrix systems and methods for constructing and displaying ligands
ATE242485T1 (de) 1993-05-28 2003-06-15 Baylor College Medicine Verfahren und massenspektrometer zur desorption und ionisierung von analyten
US5624711A (en) * 1995-04-27 1997-04-29 Affymax Technologies, N.V. Derivatization of solid supports and methods for oligomer synthesis
US5807758A (en) * 1995-07-21 1998-09-15 Lee; Gil U. Chemical and biological sensor using an ultra-sensitive force transducer
US5624668A (en) * 1995-09-29 1997-04-29 Luitpold Pharmaceuticals, Inc. Iron dextran formulations
US5705813A (en) 1995-11-01 1998-01-06 Hewlett-Packard Company Integrated planar liquid handling system for maldi-TOF MS
US20050003431A1 (en) * 1996-08-16 2005-01-06 Wucherpfennig Kai W. Monovalent, multivalent, and multimeric MHC binding domain fusion proteins and conjugates, and uses therefor
US6133436A (en) 1996-11-06 2000-10-17 Sequenom, Inc. Beads bound to a solid support and to nucleic acids
US5900481A (en) 1996-11-06 1999-05-04 Sequenom, Inc. Bead linkers for immobilizing nucleic acids to solid supports
US5792331A (en) * 1996-12-19 1998-08-11 Dionex Corporation Preformed polymer coating process and product
US5858653A (en) * 1997-09-30 1999-01-12 Surmodics, Inc. Reagent and method for attaching target molecules to a surface
US7427678B2 (en) * 1998-01-08 2008-09-23 Sigma-Aldrich Co. Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method
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US20040091602A1 (en) * 2000-10-04 2004-05-13 Hwang Hyun Jin Method for immobilizing biologically active molecules
ES2545526T3 (es) * 2001-02-01 2015-09-11 Sigma-Aldrich Co. Llc Matrices de afinidad mejorada con visibilidad mejorada para aplicaciones de arrastre molecular e inmunoprecipitación
US7135288B2 (en) * 2002-09-27 2006-11-14 Ut-Battelle, Llc Combinatorial synthesis of ceramic materials
US7373255B2 (en) * 2003-06-06 2008-05-13 Biacore Ab Method and system for determination of molecular interaction parameters

Also Published As

Publication number Publication date
EP1421386A4 (en) 2004-08-18
EP1421386A2 (en) 2004-05-26
US20050123968A1 (en) 2005-06-09
JP2005514583A (ja) 2005-05-19
US20050118709A1 (en) 2005-06-02
WO2002092834A8 (en) 2004-04-29
WO2002092834A3 (en) 2004-03-18
US20050119415A1 (en) 2005-06-02
WO2002092834A2 (en) 2002-11-21
US20030032013A1 (en) 2003-02-13
CA2446502A1 (en) 2002-11-21
US6825032B2 (en) 2004-11-30

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Effective date: 20140429