CA2439475C - Carbamate compounds for use in preventing or treating bipolar disorder - Google Patents

Carbamate compounds for use in preventing or treating bipolar disorder Download PDF

Info

Publication number
CA2439475C
CA2439475C CA2439475A CA2439475A CA2439475C CA 2439475 C CA2439475 C CA 2439475C CA 2439475 A CA2439475 A CA 2439475A CA 2439475 A CA2439475 A CA 2439475A CA 2439475 C CA2439475 C CA 2439475C
Authority
CA
Canada
Prior art keywords
formula
enantiomer
phenyl
alkyl
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2439475A
Other languages
English (en)
French (fr)
Other versions
CA2439475A1 (en
Inventor
Carlos R. Plata-Salaman
Boyu Zhao
Roy E. Twyman
Yong Moon Choi
Robert Gordon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SK Biopharmaceuticals Co Ltd
Original Assignee
Ortho McNeil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc
Publication of CA2439475A1 publication Critical patent/CA2439475A1/en
Application granted granted Critical
Publication of CA2439475C publication Critical patent/CA2439475C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Hydrogenated Pyridines (AREA)
CA2439475A 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder Expired - Fee Related CA2439475C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US27168101P 2001-02-27 2001-02-27
US60/271,681 2001-02-27
US10/081,766 2002-02-21
US10/081,766 US6562867B2 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder
PCT/US2002/005297 WO2002067921A1 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder

Publications (2)

Publication Number Publication Date
CA2439475A1 CA2439475A1 (en) 2002-09-06
CA2439475C true CA2439475C (en) 2010-05-18

Family

ID=26765948

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2439475A Expired - Fee Related CA2439475C (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder

Country Status (26)

Country Link
US (1) US6562867B2 (cg-RX-API-DMAC7.html)
EP (1) EP1408953B1 (cg-RX-API-DMAC7.html)
JP (1) JP4276837B2 (cg-RX-API-DMAC7.html)
KR (1) KR100946944B1 (cg-RX-API-DMAC7.html)
CN (1) CN1250215C (cg-RX-API-DMAC7.html)
AT (1) ATE324108T1 (cg-RX-API-DMAC7.html)
BR (1) BR0207644A (cg-RX-API-DMAC7.html)
CA (1) CA2439475C (cg-RX-API-DMAC7.html)
CY (1) CY1105330T1 (cg-RX-API-DMAC7.html)
CZ (1) CZ20032300A3 (cg-RX-API-DMAC7.html)
DE (1) DE60210976T2 (cg-RX-API-DMAC7.html)
DK (1) DK1408953T3 (cg-RX-API-DMAC7.html)
ES (1) ES2262801T3 (cg-RX-API-DMAC7.html)
HU (1) HUP0303243A3 (cg-RX-API-DMAC7.html)
IL (1) IL157590A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA03007717A (cg-RX-API-DMAC7.html)
MY (1) MY129304A (cg-RX-API-DMAC7.html)
NO (1) NO20033802L (cg-RX-API-DMAC7.html)
NZ (1) NZ527988A (cg-RX-API-DMAC7.html)
PL (1) PL364638A1 (cg-RX-API-DMAC7.html)
PT (1) PT1408953E (cg-RX-API-DMAC7.html)
RS (1) RS50677B (cg-RX-API-DMAC7.html)
RU (1) RU2300372C2 (cg-RX-API-DMAC7.html)
TW (1) TWI250872B (cg-RX-API-DMAC7.html)
WO (1) WO2002067921A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200307465B (cg-RX-API-DMAC7.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ523851A (en) * 2000-07-21 2004-09-24 Ortho Mcneil Pharm Inc A method for use of carbamate enantiomers in preventing or treating neuropathic pain and cluster and migraine headache-associated pain
WO2002067923A1 (en) * 2001-02-27 2002-09-06 Ortho-Mcneil Pharmaceutical, Inc. Carbamate compounds for use in preventing or treating anxiety disorders
PT1383489E (pt) * 2001-02-27 2007-06-21 Ortho Mcneil Pharm Inc Compostos carbamato para utilização na prevenção ou tratamento de distúrbios neurodegenerativos
BR0211244A (pt) 2001-07-16 2004-07-27 Ortho Mcneil Pharm Inc Compostos de carbamato para uso na prevenção ou tratamento de dor neuropática e dor associada com cefaléia em salvas e enxaqueca
NZ553813A (en) * 2004-09-16 2010-09-30 Janssen Pharmaceutica Nv Use of 2-phenyl-1, 2-ethanediol-(DI) carbamates for treating epileptogenesis and epilepsy
KR101335941B1 (ko) 2005-06-08 2013-12-04 에스케이바이오팜 주식회사 수면-각성 장애의 치료
US20070021501A1 (en) * 2005-07-12 2007-01-25 Twyman Roy E Methods of treating epileptogenesis
BRPI0718324A2 (pt) * 2006-10-30 2013-11-26 Sk Holdings Métodos para o tratamento de depressão.
CN101568333A (zh) * 2006-10-31 2009-10-28 詹森药业有限公司 广泛性发育障碍的治疗
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
KR102014615B1 (ko) * 2013-03-12 2019-08-27 (주)바이오팜솔루션즈 페닐카바메이트 화합물 및 이를 포함하는 신경보호용 조성물
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
KR102635938B1 (ko) * 2016-12-14 2024-02-13 에스케이바이오팜 주식회사 양극성 장애의 예방, 경감 또는 치료를 위한 카바메이트 화합물의 용도
BR112019025286A2 (pt) 2017-06-02 2020-06-23 Jazz Pharmaceuticals Ireland Limited Métodos e composições para tratamento de sonolência excessiva
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313692A (en) * 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3278380A (en) * 1962-02-06 1966-10-11 Armour Pharma Methods of calming employing diphenyl hydroxy carbamate compounds
US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
CN1056611C (zh) * 1994-06-16 2000-09-20 美国辉瑞有限公司 吡唑并吡啶和吡咯并吡啶,其用途和用于制备它们的中间体
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol

Also Published As

Publication number Publication date
CZ20032300A3 (cs) 2005-01-12
YU67803A (sh) 2006-08-17
RS50677B (sr) 2010-06-30
CA2439475A1 (en) 2002-09-06
KR20030087010A (ko) 2003-11-12
HUP0303243A2 (hu) 2004-01-28
MXPA03007717A (es) 2005-11-08
NZ527988A (en) 2006-01-27
IL157590A0 (en) 2004-03-28
EP1408953A1 (en) 2004-04-21
NO20033802L (no) 2003-10-22
ZA200307465B (en) 2005-03-17
WO2002067921A1 (en) 2002-09-06
HK1063436A1 (en) 2004-12-31
US6562867B2 (en) 2003-05-13
DE60210976T2 (de) 2007-05-24
DK1408953T3 (da) 2006-08-21
CN1505506A (zh) 2004-06-16
CN1250215C (zh) 2006-04-12
KR100946944B1 (ko) 2010-03-15
JP4276837B2 (ja) 2009-06-10
HUP0303243A3 (en) 2012-07-30
BR0207644A (pt) 2004-03-09
US20020198257A1 (en) 2002-12-26
RU2003128997A (ru) 2005-03-20
CY1105330T1 (el) 2010-03-03
EP1408953B1 (en) 2006-04-26
MY129304A (en) 2007-03-30
PT1408953E (pt) 2006-07-31
TWI250872B (en) 2006-03-11
ATE324108T1 (de) 2006-05-15
RU2300372C2 (ru) 2007-06-10
PL364638A1 (en) 2004-12-13
JP2004533415A (ja) 2004-11-04
ES2262801T3 (es) 2006-12-01
NO20033802D0 (no) 2003-08-26
DE60210976D1 (de) 2006-06-01

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20130221