CA2438030A1 - Methods of diagnosis of angiogenesis, compositions and methods of screening for angiogenesis modulators - Google Patents
Methods of diagnosis of angiogenesis, compositions and methods of screening for angiogenesis modulators Download PDFInfo
- Publication number
- CA2438030A1 CA2438030A1 CA002438030A CA2438030A CA2438030A1 CA 2438030 A1 CA2438030 A1 CA 2438030A1 CA 002438030 A CA002438030 A CA 002438030A CA 2438030 A CA2438030 A CA 2438030A CA 2438030 A1 CA2438030 A1 CA 2438030A1
- Authority
- CA
- Canada
- Prior art keywords
- angiogenesis
- protein
- sequence
- nucleic acid
- sequences
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78435601A | 2001-02-14 | 2001-02-14 | |
US09/784,356 | 2001-02-14 | ||
US79139001A | 2001-02-22 | 2001-02-22 | |
US09/791,390 | 2001-02-22 | ||
US28547501P | 2001-04-19 | 2001-04-19 | |
US60/285,475 | 2001-04-19 | ||
US31002501P | 2001-08-03 | 2001-08-03 | |
US60/310,025 | 2001-08-03 | ||
US35066601P | 2001-11-13 | 2001-11-13 | |
US60/350,666 | 2001-11-13 | ||
US33424401P | 2001-11-29 | 2001-11-29 | |
US60/334,244 | 2001-11-29 | ||
PCT/US2002/004915 WO2002079492A2 (en) | 2001-02-14 | 2002-02-14 | Methods of diagnosis of angiogenesis, compositions and methods of screening for angiogenesis modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2438030A1 true CA2438030A1 (en) | 2002-10-10 |
Family
ID=27559580
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002438030A Abandoned CA2438030A1 (en) | 2001-02-14 | 2002-02-14 | Methods of diagnosis of angiogenesis, compositions and methods of screening for angiogenesis modulators |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1418943A1 (de) |
JP (1) | JP2004531249A (de) |
AU (1) | AU2002257004A1 (de) |
CA (1) | CA2438030A1 (de) |
WO (1) | WO2002079492A2 (de) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030114410A1 (en) | 2000-08-08 | 2003-06-19 | Technion Research And Development Foundation Ltd. | Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis |
WO2002062945A2 (en) | 2000-10-25 | 2002-08-15 | Diadexus, Inc. | Compositions and methods relating to lung specific genes and proteins |
US7538088B2 (en) | 2002-04-26 | 2009-05-26 | California Institute Of Technology | Method for inhibiting angiogenesis by administration of the extracellular domain of D1-1 polypeptide |
US7622443B2 (en) | 2002-04-26 | 2009-11-24 | California Institute Of Technology | Method for inhibiting pro-angiogenic activities of endothelial cells selectively at a site of neoangiogenesis in a mammal by administration of the extracellular domain of D1-1 polypeptides |
WO2004024063A2 (en) * | 2002-09-11 | 2004-03-25 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
US7276589B2 (en) | 2002-11-26 | 2007-10-02 | Pdl Biopharma, Inc. | Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis |
US7285268B2 (en) | 2002-11-26 | 2007-10-23 | Pdl Biopharma, Inc. | Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis |
WO2004091383A2 (en) | 2003-04-01 | 2004-10-28 | Genzyme Corporation | Breast endothelial cell expression patterns |
EP1619499B1 (de) | 2003-04-25 | 2011-01-05 | Takeda Pharmaceutical Company Limited | Neues screening-verfahren |
US7267950B2 (en) * | 2003-05-01 | 2007-09-11 | Veridex, Lcc | Rapid extraction of RNA from cells and tissues |
US9309323B2 (en) | 2003-06-09 | 2016-04-12 | The University Of British Columbia | Methods for detecting and treating cancer |
US7833733B2 (en) | 2003-06-09 | 2010-11-16 | The University Of British Columbia | Methods for detecting and treating cancer |
EP1642137A2 (de) * | 2003-06-30 | 2006-04-05 | Genova Ltd. | Mit kardiovaskulären erfrankungen assoziierte sekretierte polypeptide |
US7485297B2 (en) | 2003-08-12 | 2009-02-03 | Dyax Corp. | Method of inhibition of vascular development using an antibody |
DE10340373A1 (de) * | 2003-08-30 | 2005-03-24 | Henkel Kgaa | Verfahren zur Bestimmung von Haarzyklus-Marken |
JP2005073621A (ja) * | 2003-09-01 | 2005-03-24 | Japan Science & Technology Agency | 脳腫瘍マーカーと脳腫瘍の診断方法 |
WO2005069855A2 (en) * | 2004-01-13 | 2005-08-04 | Rigel Pharmaceuticals, Inc. | Modulators of angiogenesis |
DK1755659T3 (da) | 2004-03-24 | 2012-02-27 | Abbott Biotherapeutics Corp | Anvendelse af anti-alfa5beta1-antistoffer til inhibering af kræftcelleproliferation |
WO2005103283A1 (ja) | 2004-04-23 | 2005-11-03 | Takeda Pharmaceutical Company Limited | 新規スクリーニング方法 |
WO2005113788A2 (en) * | 2004-05-21 | 2005-12-01 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g protein-coupled receptor kinase 6 (grk6) |
ATE543914T1 (de) * | 2005-09-01 | 2012-02-15 | Bristol Myers Squibb Co | Biomarker und verfahren zur bestimmung der empfindlichkeit gegen vegfr2 modulator. |
JP2009526861A (ja) * | 2006-02-14 | 2009-07-23 | ゲイシンガー クリニック | 血管新生標的としてのgpcr |
AU2007218158A1 (en) * | 2006-02-22 | 2007-08-30 | Philogen Spa | Vascular tumor markers |
ES2544957T3 (es) | 2006-03-21 | 2015-09-07 | Genentech, Inc. | Terapia combinada que implica antagonistas alfa5beta1 |
US7838250B1 (en) | 2006-04-04 | 2010-11-23 | Singulex, Inc. | Highly sensitive system and methods for analysis of troponin |
US20100255518A1 (en) | 2006-04-04 | 2010-10-07 | Goix Philippe J | Highly sensitive system and methods for analysis of troponin |
WO2009017833A2 (en) | 2007-08-02 | 2009-02-05 | Arresto Biosciences | Methods and compositions for treatment and diagnosis of fibrosis, tumor invasion, angiogenesis, and metastasis |
AR066170A1 (es) | 2007-09-26 | 2009-07-29 | Genentech Inc | Anti integrina alfa 5 beta 1 |
US9107935B2 (en) | 2009-01-06 | 2015-08-18 | Gilead Biologics, Inc. | Chemotherapeutic methods and compositions |
EP2216399A1 (de) * | 2009-01-30 | 2010-08-11 | Université de la Méditerranée | Humanes, lösliches CD146, Herstellung und Verwendungen |
JP6051048B2 (ja) | 2009-03-25 | 2016-12-21 | ジェネンテック, インコーポレイテッド | 新規な抗α5β1抗体及びその使用 |
WO2010144358A1 (en) | 2009-06-08 | 2010-12-16 | Singulex, Inc. | Highly sensitive biomarker panels |
JP5868176B2 (ja) | 2009-07-08 | 2016-02-24 | 株式会社ACTGen | 抗癌活性を有する抗体 |
SG178845A1 (en) | 2009-08-21 | 2012-04-27 | Gilead Biologics Inc | Catalytic domains from lysyl oxidase and loxl2 |
EP2473529B1 (de) * | 2009-09-03 | 2016-02-10 | Cancer Research Technology Limited | Clec14a inhibitoren |
-
2002
- 2002-02-14 WO PCT/US2002/004915 patent/WO2002079492A2/en not_active Application Discontinuation
- 2002-02-14 JP JP2002578493A patent/JP2004531249A/ja active Pending
- 2002-02-14 CA CA002438030A patent/CA2438030A1/en not_active Abandoned
- 2002-02-14 EP EP02726581A patent/EP1418943A1/de not_active Ceased
- 2002-02-14 AU AU2002257004A patent/AU2002257004A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2002079492A2 (en) | 2002-10-10 |
JP2004531249A (ja) | 2004-10-14 |
AU2002257004A1 (en) | 2002-10-15 |
WO2002079492A8 (en) | 2004-03-25 |
EP1418943A1 (de) | 2004-05-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |