CA2427852A1 - Method for growth of bacteria, minimising the release of endotoxins from the bacteria into the surrounding medium - Google Patents
Method for growth of bacteria, minimising the release of endotoxins from the bacteria into the surrounding medium Download PDFInfo
- Publication number
- CA2427852A1 CA2427852A1 CA002427852A CA2427852A CA2427852A1 CA 2427852 A1 CA2427852 A1 CA 2427852A1 CA 002427852 A CA002427852 A CA 002427852A CA 2427852 A CA2427852 A CA 2427852A CA 2427852 A1 CA2427852 A1 CA 2427852A1
- Authority
- CA
- Canada
- Prior art keywords
- bacteria
- culture
- carbon
- endotoxins
- energy source
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 239000002158 endotoxin Substances 0.000 title claims abstract description 74
- 238000000034 method Methods 0.000 title claims abstract description 62
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- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 45
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 45
- 239000001301 oxygen Substances 0.000 claims abstract description 45
- 239000000047 product Substances 0.000 claims abstract description 44
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 41
- 229910052799 carbon Inorganic materials 0.000 claims abstract description 39
- 230000001580 bacterial effect Effects 0.000 claims abstract description 15
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- 235000021240 caseins Nutrition 0.000 description 1
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- AIUDWMLXCFRVDR-UHFFFAOYSA-N dimethyl 2-(3-ethyl-3-methylpentyl)propanedioate Chemical class CCC(C)(CC)CCC(C(=O)OC)C(=O)OC AIUDWMLXCFRVDR-UHFFFAOYSA-N 0.000 description 1
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 description 1
- 235000019797 dipotassium phosphate Nutrition 0.000 description 1
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- 239000010452 phosphate Substances 0.000 description 1
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- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0003958A SE0003958D0 (sv) | 2000-10-31 | 2000-10-31 | Method for growth of microorganisms |
| SE0003958-6 | 2000-10-31 | ||
| PCT/SE2001/002370 WO2002036746A1 (en) | 2000-10-31 | 2001-10-30 | Method for growth of bacteria, minimising the release of endotoxins from the bacteria into the surrounding medium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2427852A1 true CA2427852A1 (en) | 2002-05-10 |
Family
ID=20281636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002427852A Abandoned CA2427852A1 (en) | 2000-10-31 | 2001-10-30 | Method for growth of bacteria, minimising the release of endotoxins from the bacteria into the surrounding medium |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7198936B2 (sv) |
| EP (1) | EP1337623A1 (sv) |
| AU (1) | AU2002212886A1 (sv) |
| CA (1) | CA2427852A1 (sv) |
| SE (1) | SE0003958D0 (sv) |
| WO (1) | WO2002036746A1 (sv) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10146445A1 (de) * | 2001-09-20 | 2003-04-24 | Aventis Pharma Gmbh | Optimierung der Temperaturshiftung bei Hochzelldichtefermentationen |
| PT1675601E (pt) * | 2003-10-13 | 2009-08-31 | Nestec Sa | Moderação do efeito de endotoxinas |
| FR2874931B1 (fr) * | 2004-09-08 | 2006-11-24 | Aventis Pharma Sa | Procede de production de polysaccharide k5 |
| DE102005054937A1 (de) * | 2005-11-17 | 2007-05-24 | Gelita Ag | Angiogenese förderndes Substrat |
| WO2015042114A1 (en) * | 2013-09-18 | 2015-03-26 | Novogy, Inc. | Fermentation process with distinct growth and production stages |
| CN110668561B (zh) * | 2019-10-31 | 2021-03-16 | 同济大学 | 一种有机复合粉末载体及其在城镇污水处理强化生物脱氮中的应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR940005589B1 (ko) | 1986-04-02 | 1994-06-21 | 다이닛뽄세이야꾸 가부시끼가이샤 | 핵산 또는 엔도톡신의 제거제 및 제거방법 |
| EP0289129A3 (en) | 1987-03-26 | 1990-10-10 | Repligen Corporation | High purity protein a preparation |
| US5101019A (en) | 1987-05-22 | 1992-03-31 | Takeda Chemical Industries, Ltd. | Method for removing pertussis endotoxin, a pertussis toxoid and its production |
| WO1989003885A1 (en) | 1987-10-27 | 1989-05-05 | Centocor, Inc. | Method of removing endotoxin contaminants |
| JPH01238534A (ja) | 1988-03-17 | 1989-09-22 | Mitsui Toatsu Chem Inc | エンドトキシンの除去方法 |
| EP0337243A1 (en) | 1988-04-14 | 1989-10-18 | F. Hoffmann-La Roche Ag | Process for purifying recombinant human interleukin-2 |
| EP0407037B1 (en) | 1989-06-12 | 1994-09-21 | Merck & Co. Inc. | Process for removing bacterial endotoxin from gram-negative polysaccharides |
| CZ28694A3 (en) | 1991-08-16 | 1994-05-18 | Merck & Co Inc | Process for preparing capsular polysaccharide free of lipid and endotoxin |
| US5342763A (en) | 1992-11-23 | 1994-08-30 | Genentech, Inc. | Method for producing polypeptide via bacterial fermentation |
| US5747663A (en) | 1994-02-07 | 1998-05-05 | Qiagen Gmbh | Process for the depletion or removal of endotoxins |
| KR19980080116A (ko) | 1997-03-27 | 1998-11-25 | 히라따 다다시 | 히알루론산 나트륨의 정제법 |
| US20030108997A1 (en) * | 2001-09-20 | 2003-06-12 | Mahr Klaus Di. | Optimizing temperature shifting in high cell density fermentations |
-
2000
- 2000-10-31 SE SE0003958A patent/SE0003958D0/sv unknown
-
2001
- 2001-10-30 US US10/415,332 patent/US7198936B2/en not_active Expired - Fee Related
- 2001-10-30 AU AU2002212886A patent/AU2002212886A1/en not_active Abandoned
- 2001-10-30 EP EP01981229A patent/EP1337623A1/en not_active Withdrawn
- 2001-10-30 WO PCT/SE2001/002370 patent/WO2002036746A1/en active Application Filing
- 2001-10-30 CA CA002427852A patent/CA2427852A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| SE0003958D0 (sv) | 2000-10-31 |
| US7198936B2 (en) | 2007-04-03 |
| EP1337623A1 (en) | 2003-08-27 |
| US20040029253A1 (en) | 2004-02-12 |
| WO2002036746A1 (en) | 2002-05-10 |
| AU2002212886A1 (en) | 2002-05-15 |
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| EEER | Examination request | ||
| FZDE | Discontinued |