CA2422424C - Compositions pharmaceutiques pour administration par voie rectale et vaginale - Google Patents

Compositions pharmaceutiques pour administration par voie rectale et vaginale Download PDF

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Publication number
CA2422424C
CA2422424C CA002422424A CA2422424A CA2422424C CA 2422424 C CA2422424 C CA 2422424C CA 002422424 A CA002422424 A CA 002422424A CA 2422424 A CA2422424 A CA 2422424A CA 2422424 C CA2422424 C CA 2422424C
Authority
CA
Canada
Prior art keywords
active ingredient
amount
dosage form
base
target area
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002422424A
Other languages
English (en)
Other versions
CA2422424A1 (fr
Inventor
S. Indiran Pather
Joseph R. Robinson
Jonathan D. Eichman
Rajendra K. Khankari
John Hontz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cima Labs Inc
Original Assignee
Cima Labs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cima Labs Inc filed Critical Cima Labs Inc
Publication of CA2422424A1 publication Critical patent/CA2422424A1/fr
Application granted granted Critical
Publication of CA2422424C publication Critical patent/CA2422424C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne des compositions pharmaceutiques comprenant des formes posologiques pouvant être administrées par voie rectale et vaginale, qui contiennent des agents effervescents comme activateurs de pénétration de médicaments. L'effervescence se produit dans le rectum ou le vagin après administration de la forme posologique ou au bout d'une durée prédéterminée consécutive à l'administration. Les agents effervescents peuvent être utilisés seuls ou en combinaison avec une matière de réglage de pH qui active davantage la dissolution et l'absorption de l'ingrédient actif.
CA002422424A 2000-09-19 2000-09-19 Compositions pharmaceutiques pour administration par voie rectale et vaginale Expired - Fee Related CA2422424C (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/025634 WO2002024170A1 (fr) 2000-09-19 2000-09-19 Compositions pharmaceutiques pour administration par voie rectale et vaginale

Publications (2)

Publication Number Publication Date
CA2422424A1 CA2422424A1 (fr) 2002-03-28
CA2422424C true CA2422424C (fr) 2009-12-01

Family

ID=21741785

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002422424A Expired - Fee Related CA2422424C (fr) 2000-09-19 2000-09-19 Compositions pharmaceutiques pour administration par voie rectale et vaginale

Country Status (5)

Country Link
EP (1) EP1318790A4 (fr)
JP (1) JP2004509142A (fr)
AU (1) AU7384700A (fr)
CA (1) CA2422424C (fr)
WO (1) WO2002024170A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1872775A1 (fr) 2006-06-29 2008-01-02 Polichem S.A. Emploi d'une matrice hydrophile contenant un dérivé polyacrylique, un éther de cellulose et un désintégrant, pour la production d'un médicament pour le traitement des troubles génitales d'une femme

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1212704A (en) * 1967-11-21 1970-11-18 Prodotti Antibiotici Spa Vaginal suppositories
US3888976A (en) * 1972-09-21 1975-06-10 William P Mlkvy Zinc and strontium ion containing effervescent mouthwash tablet
NL7302521A (en) * 1973-02-23 1974-08-27 Foaming, effervescent capsules - contg. therapeutic agents for rectal and vaginal use
JPS58152809A (ja) * 1982-03-05 1983-09-10 Eisai Co Ltd 安定な発泡性「膣」坐剤
IT1251114B (it) * 1991-07-26 1995-05-04 Farcon Ag Forme farmaceutiche antivirali per applicazione vaginale
DE4139883A1 (de) * 1991-11-29 1993-06-03 Michael Prof Dr Dittgen Verfahren zur herstellung bioadhaesiver arzneimittel
GB9523136D0 (en) * 1995-11-11 1996-01-10 Procter & Gamble Silicone-containing powders
US5646151A (en) * 1996-03-08 1997-07-08 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
US6071539A (en) * 1996-09-20 2000-06-06 Ethypharm, Sa Effervescent granules and methods for their preparation
ATE462417T1 (de) * 1998-08-13 2010-04-15 Cima Labs Inc Microemulsionen als feste dosisformen zur oralen verabreichung

Also Published As

Publication number Publication date
AU2000273847B2 (en) 2006-09-14
AU7384700A (en) 2002-04-02
EP1318790A4 (fr) 2006-02-01
JP2004509142A (ja) 2004-03-25
WO2002024170A1 (fr) 2002-03-28
EP1318790A1 (fr) 2003-06-18
CA2422424A1 (fr) 2002-03-28

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20160919