CA2403804A1 - Vegf-modulated genes and methods employing them - Google Patents

Vegf-modulated genes and methods employing them Download PDF

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Publication number
CA2403804A1
CA2403804A1 CA002403804A CA2403804A CA2403804A1 CA 2403804 A1 CA2403804 A1 CA 2403804A1 CA 002403804 A CA002403804 A CA 002403804A CA 2403804 A CA2403804 A CA 2403804A CA 2403804 A1 CA2403804 A1 CA 2403804A1
Authority
CA
Canada
Prior art keywords
vegfmg
polypeptide
expression
vegf
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002403804A
Other languages
English (en)
French (fr)
Inventor
Luca K. Rastelli
Hans-Peter Gerber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
CuraGen Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2403804A1 publication Critical patent/CA2403804A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
CA002403804A 2000-03-21 2001-03-21 Vegf-modulated genes and methods employing them Abandoned CA2403804A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19120100P 2000-03-21 2000-03-21
US60/191,201 2000-03-21
PCT/US2001/009043 WO2001070174A2 (en) 2000-03-21 2001-03-21 Vegf-modulated genes and methods employing them

Publications (1)

Publication Number Publication Date
CA2403804A1 true CA2403804A1 (en) 2001-09-27

Family

ID=22704517

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002403804A Abandoned CA2403804A1 (en) 2000-03-21 2001-03-21 Vegf-modulated genes and methods employing them

Country Status (6)

Country Link
US (3) US20020132978A1 (enExample)
EP (1) EP1290005A4 (enExample)
JP (1) JP2004501608A (enExample)
AU (2) AU2001250912B2 (enExample)
CA (1) CA2403804A1 (enExample)
WO (1) WO2001070174A2 (enExample)

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EP1644406B1 (en) 2003-07-11 2012-08-15 DeveloGen Aktiengesellschaft Use of dg153 secreted protein products for preventing and treating pancreatic diseases and/or obesity and/or metabolic syndrome
JPWO2005082412A1 (ja) * 2004-02-26 2007-10-25 株式会社ペルセウスプロテオミクス 癌の治療および予防薬
WO2005094888A1 (ja) * 2004-03-31 2005-10-13 Two Cells Co. Ltd. 損傷組織の治療剤と治療方法
EP1869076A2 (en) * 2005-03-10 2007-12-26 Genentech, Inc. Methods and compositions for modulating vascular integrity
EP2271358B1 (en) * 2008-03-25 2018-11-21 Amarantus Therapeutics, Inc. use of mesencephalic astrocyte-derived neurotrophic factor for treating Parkinson's disease
EP2280988B1 (en) * 2008-04-23 2017-05-24 Novacell Technology Inc. Angiogenic peptide
FI20080326A0 (fi) 2008-04-30 2008-04-30 Licentia Oy Neurotroofinen tekijä MANF ja sen käytöt
US9447152B2 (en) 2008-07-07 2016-09-20 Oxford Nanopore Technologies Limited Base-detecting pore
US20110229877A1 (en) 2008-07-07 2011-09-22 Oxford Nanopore Technologies Limited Enzyme-pore constructs
US9132168B2 (en) 2008-08-05 2015-09-15 University Of South Florida Methods of treating cognitive impairment
WO2010017224A2 (en) 2008-08-05 2010-02-11 University Of South Florida Methods of treating cognitive impairment
CN102113396B (zh) 2008-08-06 2013-10-16 夏普株式会社 通信系统、移动站装置以及通信方法
GB0820927D0 (en) 2008-11-14 2008-12-24 Isis Innovation Method
JP5843614B2 (ja) 2009-01-30 2016-01-13 オックスフォード ナノポア テクノロジーズ リミテッド 膜貫通配列決定における核酸構築物のためのアダプター
CA2750874A1 (en) * 2009-01-30 2010-08-05 Oxford Nanopore Technologies Limited Hybridization linkers
GB0905140D0 (en) 2009-03-25 2009-05-06 Isis Innovation Method
WO2012094600A1 (en) * 2011-01-06 2012-07-12 William Marsh Rice University Methods for treating lysosomal storage diseases using l-type ca2+ channel blockers with a 1,4 dihydropyridine structure and inhibitors of er-associated degradation
KR101939420B1 (ko) 2011-02-11 2019-01-16 옥스포드 나노포어 테크놀로지즈 리미티드 돌연변이체 세공
EA201400002A1 (ru) * 2011-06-09 2014-08-29 Юниверсити Оф Майами Способы лечения заболеваний сетчатки
JP6298404B2 (ja) 2011-07-25 2018-03-20 オックスフォード ナノポール テクノロジーズ リミテッド 膜貫通ポアを用いる二重鎖ポリヌクレオチド配列決定のためのヘアピンループ方法
CN112646019B (zh) 2012-04-10 2022-08-16 牛津纳米孔科技公开有限公司 突变胞溶素孔
EP2875154B1 (en) 2012-07-19 2017-08-23 Oxford Nanopore Technologies Limited SSB method for characterising a nucleic acid
GB201314695D0 (en) 2013-08-16 2013-10-02 Oxford Nanopore Tech Ltd Method
AU2014224432B2 (en) 2013-03-08 2019-10-24 Oxford Nanopore Technologies Limited Enzyme stalling method
GB201313477D0 (en) 2013-07-29 2013-09-11 Univ Leuven Kath Nanopore biosensors for detection of proteins and nucleic acids
GB201403096D0 (en) 2014-02-21 2014-04-09 Oxford Nanopore Tech Ltd Sample preparation method
EP3137490B1 (en) 2014-05-02 2021-01-27 Oxford Nanopore Technologies Limited Mutant pores
US10400014B2 (en) 2014-09-01 2019-09-03 Oxford Nanopore Technologies Ltd. Mutant CsgG pores
US10266885B2 (en) 2014-10-07 2019-04-23 Oxford Nanopore Technologies Ltd. Mutant pores
GB201418159D0 (en) 2014-10-14 2014-11-26 Oxford Nanopore Tech Ltd Method
GB201609220D0 (en) 2016-05-25 2016-07-06 Oxford Nanopore Tech Ltd Method
CA3077518C (en) * 2016-09-07 2021-10-19 Frederic Fellouse Synthetic antibodies against vegf and their uses
JP2021519578A (ja) * 2018-03-29 2021-08-12 ヘルシンギン ユリオピストHelsingin Yliopisto C末端cdnf断片、それらを含む医薬組成物、並びにそれらの使用
GB201807793D0 (en) 2018-05-14 2018-06-27 Oxford Nanopore Tech Ltd Method
AU2019296451B2 (en) 2018-06-29 2021-04-29 Wuhan Neurophth Biotechnology Limited Company Compositions and methods for treating leber's hereditary optic neuropathy
SG11202101032VA (en) * 2018-08-20 2021-02-25 Wuhan Neurophth Biotechnology Ltd Company Compositions and methods for treating leber's hereditary optic neuropathy
CN113025633B (zh) 2019-12-09 2024-08-27 武汉纽福斯生物科技有限公司 编码人nadh脱氢酶亚单位1蛋白的核酸及其应用

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US4758195A (en) * 1986-09-08 1988-07-19 3 W Designers, Inc. Elastomeric foam building units
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EP1869076A2 (en) * 2005-03-10 2007-12-26 Genentech, Inc. Methods and compositions for modulating vascular integrity

Also Published As

Publication number Publication date
US20020132978A1 (en) 2002-09-19
WO2001070174A2 (en) 2001-09-27
US20080166724A1 (en) 2008-07-10
AU2001250912C1 (en) 2001-10-03
EP1290005A2 (en) 2003-03-12
AU5091201A (en) 2001-10-03
JP2004501608A (ja) 2004-01-22
US20040006780A1 (en) 2004-01-08
EP1290005A4 (en) 2005-04-20
WO2001070174A8 (en) 2003-01-16
AU2001250912B2 (en) 2007-01-04
WO2001070174A3 (en) 2002-04-11

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued