DE60238038D1 - Das Überleben dopaminerger Neuronen fördernde Faktoren und deren Verwendungen - Google Patents
Das Überleben dopaminerger Neuronen fördernde Faktoren und deren VerwendungenInfo
- Publication number
- DE60238038D1 DE60238038D1 DE60238038T DE60238038T DE60238038D1 DE 60238038 D1 DE60238038 D1 DE 60238038D1 DE 60238038 T DE60238038 T DE 60238038T DE 60238038 T DE60238038 T DE 60238038T DE 60238038 D1 DE60238038 D1 DE 60238038D1
- Authority
- DE
- Germany
- Prior art keywords
- methods
- manf
- survival
- dopaminergic neuron
- promoting factors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5058—Neurological cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Psychology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27751601P | 2001-03-20 | 2001-03-20 | |
PCT/CA2002/000373 WO2002074956A2 (en) | 2001-03-20 | 2002-03-20 | Dopaminergic neuronal survival-promoting factors and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60238038D1 true DE60238038D1 (de) | 2010-12-02 |
Family
ID=23061211
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60238038T Expired - Lifetime DE60238038D1 (de) | 2001-03-20 | 2002-03-20 | Das Überleben dopaminerger Neuronen fördernde Faktoren und deren Verwendungen |
Country Status (9)
Country | Link |
---|---|
US (5) | US20020182198A1 (de) |
EP (1) | EP1373502B8 (de) |
JP (1) | JP2004528835A (de) |
AT (1) | ATE485377T1 (de) |
CA (1) | CA2441740A1 (de) |
DE (1) | DE60238038D1 (de) |
DK (1) | DK1373502T3 (de) |
ES (1) | ES2353490T3 (de) |
WO (1) | WO2002074956A2 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020182198A1 (en) | 2001-03-20 | 2002-12-05 | Commissiong John W. | Dopaminergic neuronal survival-promoting factors and uses thereof |
US7452969B2 (en) | 2002-08-30 | 2008-11-18 | Licentia Ltd | Neurotrophic factor protein and uses thereof |
EP1644406B1 (de) | 2003-07-11 | 2012-08-15 | DeveloGen Aktiengesellschaft | Verwendung von dg153 sekretierter proteinprodukte zur prevention und behandlung von pankreaserkrankungen und/oder fettleibigkeit und/oder metabolischem syndrom |
CA2633468C (en) * | 2005-12-14 | 2014-02-18 | Licentia Ltd | Novel neurotrophic factor protein and uses thereof |
JP2011515489A (ja) * | 2008-03-25 | 2011-05-19 | アマランタス・セラピューティクス・インコーポレイテッド | 神経変性障害 |
FI20080326A0 (fi) | 2008-04-30 | 2008-04-30 | Licentia Oy | Neurotroofinen tekijä MANF ja sen käytöt |
WO2011038366A1 (en) * | 2009-09-25 | 2011-03-31 | Amarantus Therapeutics, Inc. | Dopaminergic selective factors |
EP2717903B1 (de) | 2011-06-09 | 2016-08-10 | University Of Miami | Die neurotrophischen faktoren manf und cdnf zur behandlung von netzhauterkrankungen |
FI20115870A0 (fi) * | 2011-09-05 | 2011-09-05 | Urmas Arumaee | Neuroprotektiiviset soluihin tunkeutuvat peptidit |
KR20140121449A (ko) | 2012-01-24 | 2014-10-15 | 유니버시티 오브 매사추세츠 | 췌장 베타-세포 장애에서의 가용성 manf |
WO2015149005A1 (en) * | 2014-03-28 | 2015-10-01 | Buck Institute For Research On Aging | Methods and compositions for modulating the immune system |
JP7201432B2 (ja) * | 2015-11-18 | 2023-01-10 | ヘランティス ファーマ ピーエルシー | 中枢神経系疾患の鼻腔内治療に使用するためのcdnfまたはmanfを含む組成物 |
JP2021519578A (ja) * | 2018-03-29 | 2021-08-12 | ヘルシンギン ユリオピストHelsingin Yliopisto | C末端cdnf断片、それらを含む医薬組成物、並びにそれらの使用 |
CN113292656B (zh) * | 2020-02-21 | 2022-10-25 | 四川大学华西医院 | 用于防治肥胖的中脑星形胶质细胞源性神经营养因子的融合蛋白 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1220681A2 (de) * | 1999-09-16 | 2002-07-10 | Prescient Neuropharma Inc. | Überlebensfördernden neuronalen dopaminergischen faktoren und deren verwendungen |
WO2001025427A1 (fr) * | 1999-10-01 | 2001-04-12 | Kyowa Hakko Kogyo Co., Ltd. | Adn reagissant a la contrainte de cisaillement |
EP1290005A4 (de) * | 2000-03-21 | 2005-04-20 | Curagen Corp | Vegf-modulierte gene und verfahren, die diese verwenden |
US20020182198A1 (en) | 2001-03-20 | 2002-12-05 | Commissiong John W. | Dopaminergic neuronal survival-promoting factors and uses thereof |
WO2002079246A2 (en) * | 2001-03-30 | 2002-10-10 | Geneprot, Inc. | Human arginine-rich protein-related compositions |
CA2458207A1 (en) * | 2001-05-03 | 2002-11-14 | Murdoch Childrens Research Institute | Determination of a genetic predisposition for behavioural disorders |
GB0113657D0 (en) * | 2001-06-05 | 2001-07-25 | Geneprot Inc | Improved native chemical ligation with three or more components |
US7452969B2 (en) | 2002-08-30 | 2008-11-18 | Licentia Ltd | Neurotrophic factor protein and uses thereof |
US20060195915A1 (en) | 2002-08-30 | 2006-08-31 | Licentia Ltd. | Novel neurotrophic factor protein and uses thereof |
JP2011515489A (ja) | 2008-03-25 | 2011-05-19 | アマランタス・セラピューティクス・インコーポレイテッド | 神経変性障害 |
FI20080326A0 (fi) | 2008-04-30 | 2008-04-30 | Licentia Oy | Neurotroofinen tekijä MANF ja sen käytöt |
EP2717903B1 (de) | 2011-06-09 | 2016-08-10 | University Of Miami | Die neurotrophischen faktoren manf und cdnf zur behandlung von netzhauterkrankungen |
-
2002
- 2002-03-20 US US10/102,265 patent/US20020182198A1/en not_active Abandoned
- 2002-03-20 JP JP2002574347A patent/JP2004528835A/ja active Pending
- 2002-03-20 DK DK02706572.1T patent/DK1373502T3/da active
- 2002-03-20 AT AT02706572T patent/ATE485377T1/de not_active IP Right Cessation
- 2002-03-20 EP EP02706572A patent/EP1373502B8/de not_active Expired - Lifetime
- 2002-03-20 CA CA002441740A patent/CA2441740A1/en not_active Abandoned
- 2002-03-20 DE DE60238038T patent/DE60238038D1/de not_active Expired - Lifetime
- 2002-03-20 ES ES02706572T patent/ES2353490T3/es not_active Expired - Lifetime
- 2002-03-20 WO PCT/CA2002/000373 patent/WO2002074956A2/en not_active Application Discontinuation
-
2009
- 2009-08-04 US US12/535,029 patent/US8084425B2/en not_active Expired - Fee Related
-
2011
- 2011-11-28 US US13/305,025 patent/US9115208B2/en not_active Expired - Fee Related
-
2015
- 2015-06-30 US US14/755,272 patent/US20160152673A1/en not_active Abandoned
-
2017
- 2017-02-27 US US15/443,712 patent/US20170298110A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1373502A2 (de) | 2004-01-02 |
DK1373502T3 (da) | 2011-01-10 |
ES2353490T3 (es) | 2011-03-02 |
CA2441740A1 (en) | 2002-09-26 |
EP1373502B8 (de) | 2010-12-22 |
ATE485377T1 (de) | 2010-11-15 |
JP2004528835A (ja) | 2004-09-24 |
US8084425B2 (en) | 2011-12-27 |
WO2002074956A3 (en) | 2003-07-10 |
US20100119491A1 (en) | 2010-05-13 |
US20020182198A1 (en) | 2002-12-05 |
WO2002074956A2 (en) | 2002-09-26 |
US20130078220A1 (en) | 2013-03-28 |
US20160152673A1 (en) | 2016-06-02 |
US20170298110A1 (en) | 2017-10-19 |
EP1373502B1 (de) | 2010-10-20 |
US9115208B2 (en) | 2015-08-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: AMARANTUS THERAPEUTICS, INC., PALO ALTO, CALIF, US |