CA2400379A1 - Microarray methods utilizing semiconductor nanocrystals - Google Patents

Microarray methods utilizing semiconductor nanocrystals Download PDF

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Publication number
CA2400379A1
CA2400379A1 CA002400379A CA2400379A CA2400379A1 CA 2400379 A1 CA2400379 A1 CA 2400379A1 CA 002400379 A CA002400379 A CA 002400379A CA 2400379 A CA2400379 A CA 2400379A CA 2400379 A1 CA2400379 A1 CA 2400379A1
Authority
CA
Canada
Prior art keywords
array
ligand
nucleic acid
semiconductor nanocrystal
complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002400379A
Other languages
English (en)
French (fr)
Inventor
Stephen A. Empedocles
Edith Y. Wong
Vince E. Phillips
R. Hugh Daniels
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Life Technologies Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2400379A1 publication Critical patent/CA2400379A1/en
Abandoned legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346Nanoparticles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA002400379A 2000-02-16 2001-02-15 Microarray methods utilizing semiconductor nanocrystals Abandoned CA2400379A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US18284500P 2000-02-16 2000-02-16
US60/182,845 2000-02-16
US26629000P 2000-09-29 2000-09-29
US60/266,290 2000-09-29
PCT/US2001/004871 WO2001061040A1 (en) 2000-02-16 2001-02-15 Microarray methods utilizing semiconductor nanocrystals

Publications (1)

Publication Number Publication Date
CA2400379A1 true CA2400379A1 (en) 2001-08-23

Family

ID=26878485

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002400379A Abandoned CA2400379A1 (en) 2000-02-16 2001-02-15 Microarray methods utilizing semiconductor nanocrystals

Country Status (5)

Country Link
EP (1) EP1255866A4 (ja)
JP (1) JP2003522962A (ja)
AU (1) AU2001238320A1 (ja)
CA (1) CA2400379A1 (ja)
WO (1) WO2001061040A1 (ja)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7079241B2 (en) * 2000-04-06 2006-07-18 Invitrogen Corp. Spatial positioning of spectrally labeled beads
US7253435B2 (en) 1999-04-15 2007-08-07 Millipore Corporation Particles with light-polarizing codes
US6908737B2 (en) 1999-04-15 2005-06-21 Vitra Bioscience, Inc. Systems and methods of conducting multiplexed experiments
ATE418733T1 (de) * 2000-05-04 2009-01-15 Blood Res Center Kolloidzusammensetzungen für festphasen- biomolekulare analytische systeme
US7118845B2 (en) 2000-06-15 2006-10-10 3M Innovative Properties Company Multiphoton photochemical process and articles preparable thereby
US7005229B2 (en) 2002-10-02 2006-02-28 3M Innovative Properties Company Multiphoton photosensitization method
US7381516B2 (en) 2002-10-02 2008-06-03 3M Innovative Properties Company Multiphoton photosensitization system
JP2002311027A (ja) * 2001-04-09 2002-10-23 Hitachi Software Eng Co Ltd ビーズ、ビーズ製造方法、フローサイトメータ及びプログラム
EP1448800A4 (en) * 2001-11-21 2007-05-16 Applera Corp DIGITAL ASSAY
DK1456668T3 (da) 2001-12-05 2007-09-10 Sense Proteomic Ltd Proteinarrays til alleliske varianter og anvendelser deraf
FR2840687B1 (fr) 2002-06-05 2008-01-25 Bio Merieux Procede de detection simultanee de reactions d'hybridation et immunologiques et ses utilisations en diagnostic
AU2003272169A1 (en) * 2002-10-24 2004-05-13 Biacore Ab Assay with co-immobilized ligands
JP5091075B2 (ja) * 2007-09-28 2012-12-05 富士フイルム株式会社 イムノクロマトグラフ方法
JP5091074B2 (ja) * 2007-09-28 2012-12-05 富士フイルム株式会社 断片化抗体を用いたイムノクロマトグラフ方法
JP5091009B2 (ja) * 2008-05-27 2012-12-05 富士フイルム株式会社 イムノクロマトグラフ方法
JP2010004781A (ja) * 2008-06-25 2010-01-14 Canon Inc 核酸増幅装置およびそれを用いた核酸分析装置
GB2478734A (en) 2010-03-15 2011-09-21 Sense Proteomic Ltd Auto-antibody biomarkers of prostate cancer
GB201017520D0 (en) 2010-10-15 2010-12-01 Sense Proteomic Ltd Biomarkers
US9448231B2 (en) * 2011-02-28 2016-09-20 Ventana Medical Systems, Inc. Application of quantum dots for nuclear staining

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5800992A (en) * 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
WO1992016657A1 (en) * 1991-03-13 1992-10-01 E.I. Du Pont De Nemours And Company Method of identifying a nucleotide present at a defined position in a nucleic acid
US5605798A (en) * 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
EP1818417B1 (en) * 1996-07-29 2014-02-12 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses therefor
US5939021A (en) * 1997-01-23 1999-08-17 Hansen; W. Peter Homogeneous binding assay
CN1265156A (zh) * 1997-07-22 2000-08-30 拉普吉恩公司 核酸阵列上进行的扩增及其它酶反应
US5990479A (en) * 1997-11-25 1999-11-23 Regents Of The University Of California Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
WO2000017655A1 (en) * 1998-09-18 2000-03-30 Massachusetts Institute Of Technology Water-soluble fluorescent semiconductor nanocrystals
DE69905832T2 (de) * 1998-09-18 2004-02-05 Massachusetts Institute Of Technology, Cambridge Biologische Verwendungen von halbleitenden Nanokristallen
JP4630459B2 (ja) * 1998-09-24 2011-02-09 インディアナ・ユニバーシティ・リサーチ・アンド・テクノロジー・コーポレーション 水溶性発光量子ドットおよびその生体分子コンジュゲート
CA2373146A1 (en) * 1999-05-07 2000-11-16 Quantum Dot Corporation A method of detecting an analyte using semiconductor nanocrystals

Also Published As

Publication number Publication date
EP1255866A1 (en) 2002-11-13
WO2001061040A1 (en) 2001-08-23
EP1255866A4 (en) 2004-12-22
JP2003522962A (ja) 2003-07-29
AU2001238320A1 (en) 2001-08-27

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Legal Events

Date Code Title Description
FZDE Discontinued